Detalhe da pesquisa
1.
Crystal structure of a human MUC16 SEA domain reveals insight into the nature of the CA125 tumor marker.
Proteins
; 90(5): 1210-1218, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35037700
2.
2.1 Å crystal structure of the Mycobacterium tuberculosis serine hydrolase, Hip1, in its anhydro-form (Anhydrohip1).
Biochem Biophys Res Commun
; 630: 57-63, 2022 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36148729
3.
Preclinical Evaluation of a Humanized, Near-Infrared Fluorescent Antibody for Fluorescence-Guided Surgery of MUC16-Expressing Pancreatic Cancer.
Mol Pharm
; 19(10): 3586-3599, 2022 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35640060
4.
Immunological Functions and Evolutionary Emergence of Heavy-Chain Antibodies.
Trends Immunol
; 39(12): 956-960, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30314850
5.
Role of glycosylation on the ensemble of conformations in the MUC1 immunodominant epitope.
J Pept Sci
; 26(1): e3229, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31729101
6.
Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Biochemistry
; 58(6): 714-726, 2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30571096
7.
Structural basis of VHH-mediated neutralization of the food-borne pathogen Listeria monocytogenes.
J Biol Chem
; 293(35): 13626-13635, 2018 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29976754
8.
Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.
Glycobiology
; 27(7): 677-687, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28025250
9.
Directed evolution of the Escherichia coli cAMP receptor protein at the cAMP pocket.
J Biol Chem
; 290(44): 26587-96, 2015 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26378231
10.
Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N-glycan phosphorylation in a branch-specific manner.
Glycobiology
; 26(2): 181-92, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26503547
11.
Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS.
Proc Natl Acad Sci U S A
; 109(51): 20877-82, 2012 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23184990
12.
Untangling structure-function relationships in the rhomboid family of intramembrane proteases.
Biochim Biophys Acta
; 1828(12): 2862-72, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24099005
13.
Interrogating the Theranostic Capacity of a MUC16-Targeted Antibody for Ovarian Cancer.
J Nucl Med
; 65(4): 580-585, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38485271
14.
Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6.
Mol Cancer Ther
; 23(6): 836-853, 2024 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38394685
15.
Exploring the cross-reactivity of S25-2: complex with a 5,6-dehydro-Kdo disaccharide.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 69(Pt 1): 2-5, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23295476
16.
Antibody recognition of a unique tumor-specific glycopeptide antigen.
Proc Natl Acad Sci U S A
; 107(22): 10056-61, 2010 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20479270
17.
Crystal structure of the N-lobe of lactoferrin binding protein B from Moraxella bovis.
Biochem Cell Biol
; 90(3): 351-61, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22332934
18.
X-ray Crystal Structure Analysis of VHH-Protein Antigen Complexes.
Methods Mol Biol
; 2446: 513-530, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35157291
19.
ImmunoPET of Ovarian and Pancreatic Cancer with AR9.6, a Novel MUC16-Targeted Therapeutic Antibody.
Clin Cancer Res
; 28(5): 948-959, 2022 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34907079
20.
A common NH53K mutation in the combining site of antibodies raised against chlamydial LPS glycoconjugates significantly increases avidity.
Biochemistry
; 50(16): 3357-68, 2011 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21405106