Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Spatial CRISPR genomics identifies regulators of the tumor microenvironment.

Dhainaut, Maxime; Rose, Samuel A; Akturk, Guray; Wroblewska, Aleksandra; Nielsen, Sebastian R; Park, Eun Sook; Buckup, Mark; Roudko, Vladimir; Pia, Luisanna; Sweeney, Robert; Le Berichel, Jessica; Wilk, C Matthias; Bektesevic, Anela; Lee, Brian H; Bhardwaj, Nina; Rahman, Adeeb H; Baccarini, Alessia; Gnjatic, Sacha; Pe'er, Dana; Merad, Miriam; Brown, Brian D.

Cell ; 185(7): 1223-1239.e20, 2022 03 31.

Artigo em Inglês | MEDLINE | ID: mdl-35290801

2.

TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer.

Park, Matthew D; Reyes-Torres, Ivan; LeBerichel, Jessica; Hamon, Pauline; LaMarche, Nelson M; Hegde, Samarth; Belabed, Meriem; Troncoso, Leanna; Grout, John A; Magen, Assaf; Humblin, Etienne; Nair, Achuth; Molgora, Martina; Hou, Jinchao; Newman, Jenna H; Farkas, Adam M; Leader, Andrew M; Dawson, Travis; D'Souza, Darwin; Hamel, Steven; Sanchez-Paulete, Alfonso Rodriguez; Maier, Barbara; Bhardwaj, Nina; Martin, Jerome C; Kamphorst, Alice O; Kenigsberg, Ephraim; Casanova-Acebes, Maria; Horowitz, Amir; Brown, Brian D; De Andrade, Lucas Ferrari; Colonna, Marco; Marron, Thomas U; Merad, Miriam.

Nat Immunol ; 24(5): 792-801, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37081148

3.

"America First" Will Destroy U.S. Science.

Brown, Brian D; Leader, Andrew M; Vilcek, Jan; Merad, Miriam.

Cell ; 183(4): 841-844, 2020 11 12.

Artigo em Inglês | MEDLINE | ID: mdl-32949492

4.

The cis-Regulatory Atlas of the Mouse Immune System.

Yoshida, Hideyuki; Lareau, Caleb A; Ramirez, Ricardo N; Rose, Samuel A; Maier, Barbara; Wroblewska, Aleksandra; Desland, Fiona; Chudnovskiy, Aleksey; Mortha, Arthur; Dominguez, Claudia; Tellier, Julie; Kim, Edy; Dwyer, Dan; Shinton, Susan; Nabekura, Tsukasa; Qi, YiLin; Yu, Bingfei; Robinette, Michelle; Kim, Ki-Wook; Wagers, Amy; Rhoads, Andrew; Nutt, Stephen L; Brown, Brian D; Mostafavi, Sara; Buenrostro, Jason D; Benoist, Christophe.

Cell ; 176(4): 897-912.e20, 2019 02 07.

Artigo em Inglês | MEDLINE | ID: mdl-30686579

5.

A microRNA expression and regulatory element activity atlas of the mouse immune system.

Rose, Samuel A; Wroblewska, Aleksandra; Dhainaut, Maxime; Yoshida, Hideyuki; Shaffer, Jonathan M; Bektesevic, Anela; Ben-Zvi, Benjamin; Rhoads, Andrew; Kim, Edy Y; Yu, Bingfei; Lavin, Yonit; Merad, Miriam; Buenrostro, Jason D; Brown, Brian D.

Nat Immunol ; 22(7): 914-927, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34099919

6.

Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens.

Wroblewska, Aleksandra; Dhainaut, Maxime; Ben-Zvi, Benjamin; Rose, Samuel A; Park, Eun Sook; Amir, El-Ad David; Bektesevic, Anela; Baccarini, Alessia; Merad, Miriam; Rahman, Adeeb H; Brown, Brian D.

Cell ; 175(4): 1141-1155.e16, 2018 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-30343902

7.

RNA vaccines: A transformational advance.

Brown, Brian D; Fauci, Anthony S; Belkaid, Yasmine; Merad, Miriam.

Immunity ; 56(12): 2665-2669, 2023 Dec 12.

Artigo em Inglês | MEDLINE | ID: mdl-38091944

8.

An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis.

LaMarche, Nelson M; Hegde, Samarth; Park, Matthew D; Maier, Barbara B; Troncoso, Leanna; Le Berichel, Jessica; Hamon, Pauline; Belabed, Meriem; Mattiuz, Raphaël; Hennequin, Clotilde; Chin, Theodore; Reid, Amanda M; Reyes-Torres, Iván; Nemeth, Erika; Zhang, Ruiyuan; Olson, Oakley C; Doroshow, Deborah B; Rohs, Nicholas C; Gomez, Jorge E; Veluswamy, Rajwanth; Hall, Nicole; Venturini, Nicholas; Ginhoux, Florent; Liu, Zhaoyuan; Buckup, Mark; Figueiredo, Igor; Roudko, Vladimir; Miyake, Kensuke; Karasuyama, Hajime; Gonzalez-Kozlova, Edgar; Gnjatic, Sacha; Passegué, Emmanuelle; Kim-Schulze, Seunghee; Brown, Brian D; Hirsch, Fred R; Kim, Brian S; Marron, Thomas U; Merad, Miriam.

Nature ; 625(7993): 166-174, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38057662

9.

Immunology of COVID-19: Current State of the Science.

Vabret, Nicolas; Britton, Graham J; Gruber, Conor; Hegde, Samarth; Kim, Joel; Kuksin, Maria; Levantovsky, Rachel; Malle, Louise; Moreira, Alvaro; Park, Matthew D; Pia, Luisanna; Risson, Emma; Saffern, Miriam; Salomé, Bérengère; Esai Selvan, Myvizhi; Spindler, Matthew P; Tan, Jessica; van der Heide, Verena; Gregory, Jill K; Alexandropoulos, Konstantina; Bhardwaj, Nina; Brown, Brian D; Greenbaum, Benjamin; Gümüs, Zeynep H; Homann, Dirk; Horowitz, Amir; Kamphorst, Alice O; Curotto de Lafaille, Maria A; Mehandru, Saurabh; Merad, Miriam; Samstein, Robert M.

Immunity ; 52(6): 910-941, 2020 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-32505227

10.

TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation.

Nair-Gupta, Priyanka; Baccarini, Alessia; Tung, Navpreet; Seyffer, Fabian; Florey, Oliver; Huang, Yunjie; Banerjee, Meenakshi; Overholtzer, Michael; Roche, Paul A; Tampé, Robert; Brown, Brian D; Amsen, Derk; Whiteheart, Sidney W; Blander, J Magarian.

Cell ; 158(3): 506-21, 2014 Jul 31.

Artigo em Inglês | MEDLINE | ID: mdl-25083866

11.

Quiescent Tissue Stem Cells Evade Immune Surveillance.

Agudo, Judith; Park, Eun Sook; Rose, Samuel A; Alibo, Eziwoma; Sweeney, Robert; Dhainaut, Maxime; Kobayashi, Koichi S; Sachidanandam, Ravi; Baccarini, Alessia; Merad, Miriam; Brown, Brian D.

Immunity ; 48(2): 271-285.e5, 2018 02 20.

Artigo em Inglês | MEDLINE | ID: mdl-29466757

12.

Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells.

Casanova-Acebes, María; Dalla, Erica; Leader, Andrew M; LeBerichel, Jessica; Nikolic, Jovan; Morales, Blanca M; Brown, Markus; Chang, Christie; Troncoso, Leanna; Chen, Steven T; Sastre-Perona, Ana; Park, Matthew D; Tabachnikova, Alexandra; Dhainaut, Maxime; Hamon, Pauline; Maier, Barbara; Sawai, Catherine M; Agulló-Pascual, Esperanza; Schober, Markus; Brown, Brian D; Reizis, Boris; Marron, Thomas; Kenigsberg, Ephraim; Moussion, Christine; Benaroch, Philippe; Aguirre-Ghiso, Julio A; Merad, Miriam.

Nature ; 595(7868): 578-584, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34135508

13.

Accelerating diabetic wound healing by ROS-scavenging lipid nanoparticle-mRNA formulation.

Wang, Siyu; Zhang, Yuebao; Zhong, Yichen; Xue, Yonger; Liu, Zhengwei; Wang, Chang; Kang, Diana D; Li, Haoyuan; Hou, Xucheng; Tian, Meng; Cao, Dinglingge; Wang, Leiming; Guo, Kaiyuan; Deng, Binbin; McComb, David W; Merad, Miriam; Brown, Brian D; Dong, Yizhou.

Proc Natl Acad Sci U S A ; 121(22): e2322935121, 2024 May 28.

Artigo em Inglês | MEDLINE | ID: mdl-38771877

14.

The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.

Agudo, Judith; Ruzo, Albert; Tung, Navpreet; Salmon, Hélène; Leboeuf, Marylène; Hashimoto, Daigo; Becker, Christian; Garrett-Sinha, Lee-Ann; Baccarini, Alessia; Merad, Miriam; Brown, Brian D.

Nat Immunol ; 15(1): 54-62, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24270517

15.

Author Correction: A conserved dendritic-cell regulatory program limits antitumour immunity.

Maier, Barbara; Leader, Andrew M; Chen, Steven T; Tung, Navpreet; Chang, Christie; LeBerichel, Jessica; Chudnovskiy, Aleksey; Maskey, Shrisha; Walker, Laura; Finnigan, John P; Kirkling, Margaret E; Reizis, Boris; Ghosh, Sourav; D'Amore, Natalie Roy; Bhardwaj, Nina; Rothlin, Carla V; Wolf, Andrea; Flores, Raja; Marron, Thomas; Rahman, Adeeb H; Kenigsberg, Ephraim; Brown, Brian D; Merad, Miriam.

Nature ; 582(7813): E17, 2020 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-32499658

16.

A conserved dendritic-cell regulatory program limits antitumour immunity.

Maier, Barbara; Leader, Andrew M; Chen, Steven T; Tung, Navpreet; Chang, Christie; LeBerichel, Jessica; Chudnovskiy, Aleksey; Maskey, Shrisha; Walker, Laura; Finnigan, John P; Kirkling, Margaret E; Reizis, Boris; Ghosh, Sourav; D'Amore, Natalie Roy; Bhardwaj, Nina; Rothlin, Carla V; Wolf, Andrea; Flores, Raja; Marron, Thomas; Rahman, Adeeb H; Kenigsberg, Ephraim; Brown, Brian D; Merad, Miriam.

Nature ; 580(7802): 257-262, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-32269339

17.

Silence of the ROS.

Agudo, Judith; Brown, Brian D.

Immunity ; 44(3): 520-522, 2016 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-26982360

18.

Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

Salmon, Hélène; Idoyaga, Juliana; Rahman, Adeeb; Leboeuf, Marylène; Remark, Romain; Jordan, Stefan; Casanova-Acebes, Maria; Khudoynazarova, Makhzuna; Agudo, Judith; Tung, Navpreet; Chakarov, Svetoslav; Rivera, Christina; Hogstad, Brandon; Bosenberg, Marcus; Hashimoto, Daigo; Gnjatic, Sacha; Bhardwaj, Nina; Palucka, Anna Karolina; Brown, Brian D; Brody, Joshua; Ginhoux, Florent; Merad, Miriam.

Immunity ; 44(4): 924-38, 2016 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-27096321

19.

Deciphering the transcriptional network of the dendritic cell lineage.

Miller, Jennifer C; Brown, Brian D; Shay, Tal; Gautier, Emmanuel L; Jojic, Vladimir; Cohain, Ariella; Pandey, Gaurav; Leboeuf, Marylene; Elpek, Kutlu G; Helft, Julie; Hashimoto, Daigo; Chow, Andrew; Price, Jeremy; Greter, Melanie; Bogunovic, Milena; Bellemare-Pelletier, Angelique; Frenette, Paul S; Randolph, Gwendalyn J; Turley, Shannon J; Merad, Miriam.

Nat Immunol ; 13(9): 888-99, 2012 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-22797772

20.

High-complexity extracellular barcoding using a viral hemagglutinin.

Mullokandov, Gavriel; Vijayakumar, Gayathri; Leon, Paul; Henry, Carole; Wilson, Patrick C; Krammer, Florian; Palese, Peter; Brown, Brian D.

Proc Natl Acad Sci U S A ; 117(6): 2767-2769, 2020 02 11.

Artigo em Inglês | MEDLINE | ID: mdl-31988118

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