Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Centrosome amplification promotes cell invasion via cell-cell contact disruption and Rap-1 activation.

Prakash, Anu; Paunikar, Shishir; Webber, Mark; McDermott, Emma; Vellanki, Sri H; Thompson, Kerry; Dockery, Peter; Jahns, Hanne; Brown, James A L; Hopkins, Ann M; Bourke, Emer.

J Cell Sci ; 136(21)2023 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-37772773

2.

Circulating microRNAs miR-331 and miR-195 differentiate local luminal a from metastatic breast cancer.

McAnena, Peter; Tanriverdi, Kahraman; Curran, Catherine; Gilligan, K; Freedman, Jane E; Brown, James A L; Kerin, Michael J.

BMC Cancer ; 19(1): 436, 2019 May 10.

Artigo em Inglês | MEDLINE | ID: mdl-31077182

3.

Correction to: Breast cancer subtype discordance: impact on post-recurrence survival and potential treatment options.

McAnena, Peter F; McGuire, Andrew; Ramli, A; Curran, C; Malone, C; McLaughlin, R; Barry, K; Brown, James A L; Kerin, M J.

BMC Cancer ; 18(1): 282, 2018 03 13.

Artigo em Inglês | MEDLINE | ID: mdl-29534688

4.

Breast cancer subtype discordance: impact on post-recurrence survival and potential treatment options.

McAnena, Peter F; McGuire, Andrew; Ramli, A; Curran, C; Malone, C; McLaughlin, R; Barry, K; Brown, James A L; Kerin, M J.

BMC Cancer ; 18(1): 203, 2018 02 20.

Artigo em Inglês | MEDLINE | ID: mdl-29463223

5.

Clinically Applicable Inhibitors Impacting Genome Stability.

Prakash, Anu; Garcia-Moreno, Juan F; Brown, James A L; Bourke, Emer.

Molecules ; 23(5)2018 May 13.

Artigo em Inglês | MEDLINE | ID: mdl-29757235

6.

Differential impact of hormone receptor status on survival and recurrence for HER2 receptor-positive breast cancers treated with Trastuzumab.

McGuire, Andrew; Kalinina, Olga; Holian, Emma; Curran, Catherine; Malone, Carmel A; McLaughlin, Ray; Lowery, Aoife; Brown, James A L; Kerin, Michael J.

Breast Cancer Res Treat ; 164(1): 221-229, 2017 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-28378298

7.

Metastatic breast cancer: the potential of miRNA for diagnosis and treatment monitoring.

McGuire, Andrew; Brown, James A L; Kerin, Michael J.

Cancer Metastasis Rev ; 34(1): 145-55, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25721950

8.

Targeting cancer using KAT inhibitors to mimic lethal knockouts.

Brown, James A L; Bourke, Emer; Eriksson, Leif A; Kerin, Michael J.

Biochem Soc Trans ; 44(4): 979-86, 2016 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-27528742

9.

Smg1 haploinsufficiency predisposes to tumor formation and inflammation.

Roberts, Tara L; Ho, Uda; Luff, John; Lee, C Soon; Apte, Simon H; MacDonald, Kelli P A; Raggat, Liza J; Pettit, Allison R; Morrow, Carl A; Waters, Michael J; Chen, Phil; Woods, Rick G; Thomas, Gethin P; St Pierre, Liam; Farah, Camile S; Clarke, Raymond A; Brown, James A L; Lavin, Martin F.

Proc Natl Acad Sci U S A ; 110(4): E285-94, 2013 Jan 22.

Artigo em Inglês | MEDLINE | ID: mdl-23277562

10.

Multiple facets of the DNA damage response contribute to the radioresistance of mouse mesenchymal stromal cell lines.

Sugrue, Tara; Brown, James A L; Lowndes, Noel F; Ceredig, Rhodri.

Stem Cells ; 31(1): 137-45, 2013 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-22961695

11.

Profiling leadership: Attitudes, knowledge and training in the biological sciences.

Brown, James A L.

PLoS One ; 18(6): e0286826, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37285357

12.

Peripheral Blood Cell Ratios as Prognostic Indicators in a Neoadjuvant Chemotherapy-Treated Breast Cancer Cohort.

Jalali, Amirhossein; Miresse, David; Fahey, Matthew R; Ni Mhaonaigh, Niamh; McGuire, Andrew; Bourke, Emer; Kerin, Michael J; Brown, James A L.

Curr Oncol ; 29(10): 7512-7523, 2022 10 07.

Artigo em Inglês | MEDLINE | ID: mdl-36290868

13.

A Novel Mechanism of Ataxia Telangiectasia Mutated Mediated Regulation of Chromatin Remodeling in Hypoxic Conditions.

Likhatcheva, Maria; Gieling, Roben G; Brown, James A L; Demonacos, Constantinos; Williams, Kaye J.

Front Cell Dev Biol ; 9: 720194, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34621741

14.

Recent Advances in the Role of Discoidin Domain Receptor Tyrosine Kinase 1 and Discoidin Domain Receptor Tyrosine Kinase 2 in Breast and Ovarian Cancer.

Chen, Li; Kong, Xiangyi; Fang, Yi; Paunikar, Shishir; Wang, Xiangyu; Brown, James A L; Bourke, Emer; Li, Xingrui; Wang, Jing.

Front Cell Dev Biol ; 9: 747314, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34805157

15.

Prospective Assessment of Systemic MicroRNAs as Markers of Response to Neoadjuvant Chemotherapy in Breast Cancer.

McGuire, Andrew; Casey, Maire-Caitlin; Waldron, Ronan M; Heneghan, Helen; Kalinina, Olga; Holian, Emma; McDermott, Ailbhe; Lowery, Aoife J; Newell, John; Dwyer, Róisín M; Miller, Nicola; Keane, Maccon; Brown, James A L; Kerin, Michael J.

Cancers (Basel) ; 12(7)2020 Jul 07.

Artigo em Inglês | MEDLINE | ID: mdl-32645898

16.

Recent Advances in Understanding FOXN3 in Breast Cancer, and Other Malignancies.

Kong, Xiangyi; Zhai, Jie; Yan, Chengrui; Song, Yan; Wang, Jing; Bai, Xiaofeng; Brown, James A L; Fang, Yi.

Front Oncol ; 9: 234, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31214487

17.

In Vitro Histone Acetylation Assay.

Brown, James A L.

Curr Protoc Pharmacol ; 79: 3.14.1-3.14.16, 2017 Dec 20.

Artigo em Inglês | MEDLINE | ID: mdl-29261229

18.

Practical Bioinformatics Analysis of MiRNA Data Using Online Tools.

Brown, James A L; Bourke, Emer.

Methods Mol Biol ; 1509: 195-208, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-27826929

19.

Circulating Nucleosomes and Nucleosome Modifications as Biomarkers in Cancer.

McAnena, Peter; Brown, James A L; Kerin, Michael J.

Cancers (Basel) ; 9(1)2017 Jan 08.

Artigo em Inglês | MEDLINE | ID: mdl-28075351

20.

Editorial: Cancer Therapeutics: Targeting DNA Repair Pathways.

Suraweera, Amila; Brown, James A L; Lim, Yi Chieh; Lavin, Martin F.

Front Mol Biosci ; 9: 858514, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35242815

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