Detalhe da pesquisa
1.
In vitro induction of T regulatory cells by a methylated CpG DNA sequence in humans: Potential therapeutic applications in allergic and autoimmune diseases.
Allergy Asthma Proc
; 39(2): 143-152, 2018 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29490770
2.
BRCA1-mimetic compound NSC35446.HCl inhibits IKKB expression by reducing estrogen receptor-α occupancy in the IKKB promoter and inhibits NF-κB activity in antiestrogen-resistant human breast cancer cells.
Breast Cancer Res Treat
; 166(3): 681-693, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28808806
3.
Development of a novel near-infrared fluorescent theranostic combretastain A-4 analogue, YK-5-252, to target triple negative breast cancer.
Bioorg Med Chem
; 25(7): 2226-2233, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28284864
4.
Aminopeptidase P Mediated Targeting for Breast Tissue Specific Conjugate Delivery.
Bioconjug Chem
; 27(9): 1981-90, 2016 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26965452
5.
STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain.
Proc Natl Acad Sci U S A
; 110(4): 1267-72, 2013 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23288901
6.
DIM (3,3'-diindolylmethane) confers protection against ionizing radiation by a unique mechanism.
Proc Natl Acad Sci U S A
; 110(46): 18650-5, 2013 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24127581
7.
Preclinical studies of the potent and selective nicotinic α4ß2 receptor ligand VMY-2-95.
Mol Pharm
; 12(2): 393-402, 2015 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25533629
8.
Synthesis and pharmacological characterization of new neuronal nicotinic acetylcholine receptor ligands derived from Sazetidine-A.
Bioorg Med Chem Lett
; 24(13): 2954-6, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24844195
9.
Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma.
Bioorg Med Chem
; 22(1): 478-87, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24326277
10.
Mechanisms of unphosphorylated STAT3 transcription factor binding to DNA.
J Biol Chem
; 287(17): 14192-200, 2012 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22378781
11.
Preclinical studies of YK-4-272, an inhibitor of class II histone deacetylases by disruption of nucleocytoplasmic shuttling.
Pharm Res
; 29(12): 3373-83, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22836184
12.
Synthesis and biological evaluation of a fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain and imaging agent.
Bioorg Med Chem
; 20(17): 5269-76, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863530
13.
Asymmetric synthesis and evaluation of a hydroxyphenylamide voltage-gated sodium channel blocker in human prostate cancer xenografts.
Bioorg Med Chem
; 20(6): 2180-8, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22364743
14.
Fluorescent cyclin-dependent kinase inhibitors block the proliferation of human breast cancer cells.
Bioorg Med Chem
; 19(8): 2714-25, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21440449
15.
Synthesis and evaluation of hermitamides A and B as human voltage-gated sodium channel blockers.
Bioorg Med Chem
; 19(14): 4322-9, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21683602
16.
Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats.
J Pharmacol Exp Ther
; 332(3): 933-9, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20007754
17.
A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent.
Bioorg Med Chem
; 18(2): 971-7, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20006519
18.
Synthesis of C-glycoside analogues of beta-galactosamine-(1-->4)-3-O-methyl-D-chiro-inositol and assay as activator of protein phosphatases PDHP and PP2Calpha.
Bioorg Med Chem
; 18(3): 1103-10, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20079654
19.
AMP-activated protein kinase promotes human prostate cancer cell growth and survival.
Mol Cancer Ther
; 8(4): 733-41, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19372545
20.
Modulation of sodium channel inactivation gating by a novel lactam: implications for seizure suppression in chronic limbic epilepsy.
J Pharmacol Exp Ther
; 328(1): 201-12, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18952887