Detalhe da pesquisa
1.
Src Cooperates with Oncogenic Ras in Tumourigenesis via the JNK and PI3K Pathways in Drosophila epithelial Tissue.
Int J Mol Sci
; 19(6)2018 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29861494
2.
The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state.
PLoS Genet
; 9(7): e1003627, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23874226
3.
Using Drosophila melanogaster to map human cancer pathways.
Nat Rev Cancer
; 5(8): 626-39, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16034367
4.
Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling.
BMC Dev Biol
; 11: 57, 2011 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21955824
5.
New tricks for old dogs: unexpected roles for cell cycle regulators revealed using animal models.
Curr Opin Cell Biol
; 16(6): 614-22, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15530771
6.
Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.
BMC Biol
; 7: 62, 2009 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19778415
7.
Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye.
Dev Biol
; 311(1): 106-23, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17870065
8.
hScrib is a functional homologue of the Drosophila tumour suppressor Scribble.
Oncogene
; 22(58): 9225-30, 2003 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-14681682
9.
Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis.
Biol Open
; 4(8): 1024-39, 2015 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26187947
10.
BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila.
PLoS One
; 10(7): e0132987, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26207831
11.
In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling.
Dis Model Mech
; 6(3): 661-78, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23324326
12.
An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery.
Dis Model Mech
; 6(2): 521-9, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22996645
13.
Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.
Genetics
; 188(1): 105-25, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21368274
14.
scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila.
EMBO J
; 22(21): 5769-79, 2003 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-14592975
15.
Drosophila cyclin E interacts with components of the Brahma complex.
EMBO J
; 21(13): 3377-89, 2002 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12093739