Detalhe da pesquisa
1.
Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotides.
Nucleic Acids Res
; 51(10): 4713-4725, 2023 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37099382
2.
Molecular basis of Arginine and Lysine DNA sequence-dependent thermo-stability modulation.
PLoS Comput Biol
; 18(1): e1009749, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007284
3.
The Impact of the HydroxyMethylCytosine epigenetic signature on DNA structure and function.
PLoS Comput Biol
; 17(11): e1009547, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34748533
4.
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope.
Proc Natl Acad Sci U S A
; 116(20): 10009-10018, 2019 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31028138
5.
Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs.
J Chem Inf Model
; 60(12): 5730-5734, 2020 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32672454
6.
Rational design of novel N-alkyl-N capped biostable RNA nanostructures for efficient long-term inhibition of gene expression.
Nucleic Acids Res
; 44(9): 4354-67, 2016 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26975656
7.
Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway.
Nat Commun
; 14(1): 3318, 2023 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37308482
8.
Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair.
Nat Commun
; 14(1): 5104, 2023 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607906
9.
Rational optimization of a transcription factor activation domain inhibitor.
Nat Struct Mol Biol
; 30(12): 1958-1969, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38049566
10.
Mechanism of reaction of RNA-dependent RNA polymerase from SARS-CoV-2.
Chem Catal
; 2(5): 1084-1099, 2022 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35465139
11.
A method for multiplexed full-length single-molecule sequencing of the human mitochondrial genome.
Nat Commun
; 13(1): 5902, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36202811
12.
MiOS, an integrated imaging and computational strategy to model gene folding with nucleosome resolution.
Nat Struct Mol Biol
; 29(10): 1011-1023, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36220894
13.
Differential expression of the bone and the liver tissue non-specific alkaline phosphatase isoforms in brain tissues.
Cell Tissue Res
; 343(3): 521-36, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21191615
14.
Bioactivity descriptors for uncharacterized chemical compounds.
Nat Commun
; 12(1): 3932, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34168145
15.
Impact of DNA methylation on 3D genome structure.
Nat Commun
; 12(1): 3243, 2021 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050148
16.
Hyperphosphatasia with seizures, neurologic deficit, and characteristic facial features: Five new patients with Mabry syndrome.
Am J Med Genet A
; 152A(7): 1661-9, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20578257
17.
Mild forms of hypophosphatasia mostly result from dominant negative effect of severe alleles or from compound heterozygosity for severe and moderate alleles.
BMC Med Genet
; 10: 51, 2009 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19500388
18.
A multifunctional toolkit for target-directed cancer therapy.
Chem Commun (Camb)
; 55(6): 802-805, 2019 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30574643
19.
Author Correction: Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor.
Nat Commun
; 10(1): 4605, 2019 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31591399
20.
Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor.
Nat Commun
; 10(1): 3562, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31395886