Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease.

Shi, Liu; Xu, Jin; Green, Rebecca; Wretlind, Asger; Homann, Jan; Buckley, Noel J; Tijms, Betty M; Vos, Stephanie J B; Lill, Christina M; Kate, Mara Ten; Engelborghs, Sebastiaan; Sleegers, Kristel; Frisoni, Giovanni B; Wallin, Anders; Lleó, Alberto; Popp, Julius; Martinez-Lage, Pablo; Streffer, Johannes; Barkhof, Frederik; Zetterberg, Henrik; Visser, Pieter Jelle; Lovestone, Simon; Bertram, Lars; Nevado-Holgado, Alejo J; Proitsi, Petroula; Legido-Quigley, Cristina.

Alzheimers Dement ; 19(8): 3350-3364, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-36790009

2.

Loss of Cln5 leads to altered Gad1 expression and deficits in interneuron development in mice.

Singh, Yajuvinder; Leinonen, Henri; Fazaludeen, Feroze; Jaronen, Merja; Guest, Debbie; Buckley, Noel; Byts, Nadiya; Oksa, Petra; Jalkanen, Kari; Iqbal, Imran; Huuskonen, Mikko; Savchenko, Ekaterina; Keksa-Goldsteine, Velta; Chew, Sweelin; Myllyharju, Johanna; Tanila, Heikki; Ooi, Lezanne; Koistinaho, Jari; Kanninen, Katja M; Malm, Tarja.

Hum Mol Genet ; 28(19): 3309-3322, 2019 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-31294445

3.

Δ⁹-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons.

Shum, Carole; Dutan, Lucia; Annuario, Emily; Warre-Cornish, Katherine; Taylor, Samuel E; Taylor, Ruth D; Andreae, Laura C; Buckley, Noel J; Price, Jack; Bhattacharyya, Sagnik; Srivastava, Deepak P.

Mol Cell Neurosci ; 103: 103463, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31917333

4.

Replication study of plasma proteins relating to Alzheimer's pathology.

Shi, Liu; Winchester, Laura M; Westwood, Sarah; Baird, Alison L; Anand, Sneha N; Buckley, Noel J; Hye, Abdul; Ashton, Nicholas J; Bos, Isabelle; Vos, Stephanie J B; Kate, Mara Ten; Scheltens, Philip; Teunissen, Charlotte E; Vandenberghe, Rik; Gabel, Silvy; Meersmans, Karen; Engelborghs, Sebastiaan; De Roeck, Ellen E; Sleegers, Kristel; Frisoni, Giovanni B; Blin, Olivier; Richardson, Jill C; Bordet, Régis; Molinuevo, José L; Rami, Lorena; Wallin, Anders; Kettunen, Petronella; Tsolaki, Magda; Verhey, Frans; Lléo, Alberto; Sala, Isabel; Popp, Julius; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Johannsen, Peter; Freund-Levi, Yvonne; Frölich, Lutz; Dobricic, Valerija; Legido-Quigley, Cristina; Barkhof, Frederik; Andreasson, Ulf; Blennow, Kaj; Zetterberg, Henrik; Streffer, Johannes; Lill, Christina M; Bertram, Lars; Visser, Pieter Jelle; Kolb, Hartmuth C; Narayan, Vaibhav A.

Alzheimers Dement ; 17(9): 1452-1464, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-33792144

5.

Cross-regulation between an alternative splicing activator and a transcription repressor controls neurogenesis.

Raj, Bushra; O'Hanlon, Dave; Vessey, John P; Pan, Qun; Ray, Debashish; Buckley, Noel J; Miller, Freda D; Blencowe, Benjamin J.

Mol Cell ; 43(5): 843-50, 2011 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-21884984

6.

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay.

Shi, Liu; Westwood, Sarah; Baird, Alison L; Winchester, Laura; Dobricic, Valerija; Kilpert, Fabian; Hong, Shengjun; Franke, Andre; Hye, Abdul; Ashton, Nicholas J; Morgan, Angharad R; Bos, Isabelle; Vos, Stephanie J B; Buckley, Noel J; Kate, Mara Ten; Scheltens, Philip; Vandenberghe, Rik; Gabel, Silvy; Meersmans, Karen; Engelborghs, Sebastiaan; De Roeck, Ellen E; Sleegers, Kristel; Frisoni, Giovanni B; Blin, Olivier; Richardson, Jill C; Bordet, Régis; Molinuevo, José L; Rami, Lorena; Wallin, Anders; Kettunen, Petronella; Tsolaki, Magda; Verhey, Frans; Lleó, Alberto; Alcolea, Daniel; Popp, Julius; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Johannsen, Peter; Teunissen, Charlotte E; Freund-Levi, Yvonne; Frölich, Lutz; Legido-Quigley, Cristina; Barkhof, Frederik; Blennow, Kaj; Zetterberg, Henrik; Baker, Susan; Morgan, B Paul; Streffer, Johannes; Visser, Pieter Jelle.

Alzheimers Dement ; 15(11): 1478-1488, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31495601

7.

A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets.

Castro, Diogo S; Martynoga, Ben; Parras, Carlos; Ramesh, Vidya; Pacary, Emilie; Johnston, Caroline; Drechsel, Daniela; Lebel-Potter, Mélanie; Garcia, Laura Galinanes; Hunt, Charles; Dolle, Dirk; Bithell, Angela; Ettwiller, Laurence; Buckley, Noel; Guillemot, François.

Genes Dev ; 25(9): 930-45, 2011 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-21536733

8.

Convergent molecular defects underpin diverse neurodegenerative diseases.

Tofaris, George K; Buckley, Noel J.

J Neurol Neurosurg Psychiatry ; 89(9): 962-969, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-29459380

9.

MiR-375 is Essential for Human Spinal Motor Neuron Development and May Be Involved in Motor Neuron Degeneration.

Bhinge, Akshay; Namboori, Seema C; Bithell, Angela; Soldati, Chiara; Buckley, Noel J; Stanton, Lawrence W.

Stem Cells ; 34(1): 124-34, 2016 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-26507573

10.

A Role for RE-1-Silencing Transcription Factor in Embryonic Stem Cells Cardiac Lineage Specification.

Aksoy, Irene; Marcy, Guillaume; Chen, Jiaxuan; Divakar, Ushashree; Kumar, Vibhor; John-Sanchez, Daniel; Rahmani, Mehran; Buckley, Noel J; Stanton, Lawrence W.

Stem Cells ; 34(4): 860-72, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26864965

11.

RE1 silencing transcription factor/neuron-restrictive silencing factor regulates expansion of adult mouse subventricular zone-derived neural stem/progenitor cells in vitro.

Soldati, Chiara; Caramanica, Pasquale; Burney, Matthew J; Toselli, Camilla; Bithell, Angela; Augusti-Tocco, Gabriella; Stanton, Lawrence W; Biagioni, Stefano; Buckley, Noel J; Cacci, Emanuele.

J Neurosci Res ; 93(8): 1203-14, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-25691247

12.

Concise review: a population shift view of cellular reprogramming.

Del Sol, Antonio; Buckley, Noel J.

Stem Cells ; 32(6): 1367-72, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24448890

13.

Is REST a regulator of pluripotency?

Buckley, Noel J; Johnson, Rory; Sun, Yuh-Man; Stanton, Lawrence W.

Nature ; 457(7233): E5-6; discussion E7, 2009 Feb 26.

Artigo em Inglês | MEDLINE | ID: mdl-19242418

14.

An epigenetic signature of developmental potential in neural stem cells and early neurons.

Burney, Matthew J; Johnston, Caroline; Wong, Kee-Yew; Teng, Siaw-Wei; Beglopoulos, Vassilios; Stanton, Lawrence W; Williams, Brenda P; Bithell, Angela; Buckley, Noel J.

Stem Cells ; 31(9): 1868-80, 2013 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-23712654

15.

SRRM4-mediated REST to REST4 dysregulation promotes tumor growth and neural adaptation in breast cancer leading to brain metastasis.

Deshpande, Krutika; Martirosian, Vahan; Nakamura, Brooke N; Das, Diganta; Iyer, Mukund; Reed, Max; Shao, Ling; Bamshad, Daniella; Buckley, Noel J; Neman, Josh.

Neuro Oncol ; 26(2): 309-322, 2024 02 02.

Artigo em Inglês | MEDLINE | ID: mdl-37716001

16.

Paired plasma lipidomics and proteomics analysis in the conversion from mild cognitive impairment to Alzheimer's disease.

Gómez-Pascual, Alicia; Naccache, Talel; Xu, Jin; Hooshmand, Kourosh; Wretlind, Asger; Gabrielli, Martina; Lombardo, Marta Tiffany; Shi, Liu; Buckley, Noel J; Tijms, Betty M; Vos, Stephanie J B; Ten Kate, Mara; Engelborghs, Sebastiaan; Sleegers, Kristel; Frisoni, Giovanni B; Wallin, Anders; Lleó, Alberto; Popp, Julius; Martinez-Lage, Pablo; Streffer, Johannes; Barkhof, Frederik; Zetterberg, Henrik; Visser, Pieter Jelle; Lovestone, Simon; Bertram, Lars; Nevado-Holgado, Alejo J; Gualerzi, Alice; Picciolini, Silvia; Proitsi, Petroula; Verderio, Claudia; Botía, Juan A; Legido-Quigley, Cristina.

Comput Biol Med ; 176: 108588, 2024 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-38761503

17.

Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's disease.

Soldati, Chiara; Bithell, Angela; Johnston, Caroline; Wong, Kee-Yew; Stanton, Lawrence W; Buckley, Noel J.

J Neurochem ; 124(3): 418-30, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23145961

18.

Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models.

Conforti, Paola; Zuccato, Chiara; Gaudenzi, Germano; Ieraci, Alessandro; Camnasio, Stefano; Buckley, Noel J; Mutti, Cesare; Cotelli, Franco; Contini, Alessandro; Cattaneo, Elena.

J Neurochem ; 127(1): 22-35, 2013 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-23800350

19.

Repressor element 1 silencing transcription factor couples loss of pluripotency with neural induction and neural differentiation.

Soldati, Chiara; Bithell, Angela; Johnston, Caroline; Wong, Kee-Yew; Teng, Siaw-Wei; Beglopoulos, Vassilios; Stanton, Lawrence W; Buckley, Noel J.

Stem Cells ; 30(3): 425-34, 2012 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-22162260

20.

Editorial: Our top 10 developments in stem cell biology over the last 30 years.

Armstrong, Lyle; Lako, Majlinda; Buckley, Noel; Lappin, Terry R J; Murphy, Martin J; Nolta, Jan A; Pittenger, Mark; Stojkovic, Miodrag.

Stem Cells ; 30(1): 2-9, 2012 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-22162299

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