Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 46
Filtrar
Mais filtros

País/Região como assunto
Intervalo de ano de publicação
1.
Med Oral Patol Oral Cir Bucal ; 28(6): e607-e613, 2023 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-37330957

RESUMO

BACKGROUND: The aim of our study is to evaluate the usability of the Free Gingival Graft (FGG) procedure, which is included in YouTube videos, in both patient information and student education. MATERIAL AND METHODS: A search was performed on YouTube on December 1, in 2022, using the search term ''Free Gingival Graft''. First 150 videos were pre-evaluated, and 67 videos were included in the study. The length of the videos, the number of views, the number of likes, the presence of animation and the number of months after uploading were evaluated. The quality of the videos was evaluated and analyzed with The Global Quality Score (GQS), Usefulness Score (US) and The Journal of American Medical Association (JAMA) scores. RESULTS: A positive correlation was found between viewer interaction, video duration and quality scores. The median values of the quality scores were 2 for the GQS, 2 for the JAMA score and 1 for the Usefulness score. The level of quality scores was found to be insufficient (poor quality). There is a high level, positive and statistically significant correlation between the GQS and the Usefulness score (r=0.858 and p<0.001). CONCLUSIONS: YouTube videos containing the FGG procedure were found to be insufficient for both student education and patient information purposes.


Assuntos
Procedimentos Cirúrgicos Bucais , Mídias Sociais , Humanos , Assistência Odontológica , Emoções , Reprodutibilidade dos Testes , Gravação em Vídeo , Transplantes
2.
Int J Environ Sci Technol (Tehran) ; 20(5): 5471-5490, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36213697

RESUMO

We aimed to map and analyze LAI by using Landsat 8 and Sentinel-2 time series and the corresponding ground measurements collected in pure Anatolian black pine [Pinus nigra J.F. Arnold ssp. pallasiana (Lamb.) Holmboe] stands within seven-month (from June to December) period. A total of 30 sample plots were selected and seven-month changes of LAI values were determined through hemispherical photography for each sample plot. Remote sensing (reflectance values and vegetation indices obtained from Landsat-8 and Sentinel-2) and topographic (elevation, aspect, and slope) data were used to model the LAI for each month using multiple linear regression (MLR) method. Additionally, the data for all months were combined and modeled. In this case, autoregressive modeling techniques were used to solve the temporal autocorrelation problem. Our study indicated that the models developed from Sentinel-2 give more successful results than Landsat 8 on monthly LAI models. The most successful models were obtained in June by using the reflectance values (Radj2 = 0.39, RMSE = 0.3138 m2 m-2), reflectance values-topographic data (Radj2 = 0.59, RMSE = 0.3174 m2 m-2), vegetation indices-topographic data (Radj2 = 0.82, RMSE = 0.2126 m2 m-2), and reflectance values-vegetation indices-topographic data (Radj2 = 0.93, RMSE = 0.1060 m2 m-2). Among the autoregressive modeling techniques, the highest success was obtained with the Landsat 8 OLI using the moving average (2) procedure (R2 = 0.56). This study is significant that it is the first to analyze the monthly effect on LAI modeling and mapping in pure Anatolian black pine stands using both reflectance values, vegetation indices, and topographic data.

3.
Niger J Clin Pract ; 24(11): 1694-1705, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34782511

RESUMO

BACKGROUND: To determine and compare the effects of different honey types on wound healing in an animal model, with silver sulfadiazine as the standard treatment. MATERIALS AND METHODS: Five different groups were created with eight rats in each group. Partial-depth burns were created, and different types of honey and silver sulfadiazine were applied to the respective groups. Rats were monitored for 21 days, and wound cultures were obtained. Histopathological evaluation and cytokine analysis of final tissue samples were performed. In addition, the biochemical and microbiological analyses of the four types of honey used in the study were performed. RESULTS: Wound shrinkage comparisons showed that all four honey-treated groups (Bingöl, Konya, cotton, and citrus) performed better than the silver sulfadiazine group (honey groups, respectively, 86.86%, 84.72%, 89.61%, and 95.33% vs. control 82.90%). However, only citrus honey caused a significant difference in wound shrinkage rate when compared with other groups as well with control group (95.34% vs. 82.9%, P < 0.05). In tissues, all honey groups had higher cytokine (interleukin [IL]-6, IL-1B, tumor necrosis factor [TNF]-α) values compared with controls (P < 0.001). Honey analysis showed a significant inverse relationship between Fe (iron) and the number of diastases. CONCLUSIONS: The results of this study support the role of honey in wound healing, due to its antibacterial and immunomodulatory effects. More studies are needed to identify the role of honey composition in wound healing.


Assuntos
Anti-Infecciosos Locais , Queimaduras , Mel , Animais , Queimaduras/tratamento farmacológico , Ratos , Sulfadiazina de Prata , Cicatrização
4.
Osteoporos Int ; 26(1): 273-9, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25187118

RESUMO

UNLABELLED: Sixty patients diagnosed with generalized anxiety disorder and treated with either paroxetine, sertraline, or citalopram for at least 12 months were enrolled in this study, and the bone mineral density (BMD) of the patients was compared with that of 40 healthy volunteers. Selective serotonin reuptake inhibitor (SSRI) therapy in generalized anxiety disorder was found to be related with decreased BMD values. INTRODUCTION: The objectives of this study were to evaluate the effect of SSRI therapy on BMD in postmenopausal women diagnosed with generalized anxiety disorder (GAD) and to identify the effects of the duration of disease and treatment on risk factors for osteoporosis. METHODS: Sixty patients diagnosed with GAD and treated with paroxetine, sertraline, or citalopram from the SSRI group for at least 12 months were enrolled. Social demographic features, the Hamilton Anxiety Scale (HAS) results, and the Hamilton Depression Scale (HDS) scores of all the patients were assessed. The BMD of the patients was measured by dual-energy X-ray absorptiometry (DXA) at the femoral and lumbar regions. The patients were divided into three groups which are the paroxetine, sertraline, and citalopram groups. The BMD of the patients was compared with that of 40 healthy volunteers. RESULTS: The L2-L4, total lumbar vertebrae, femoral intertrochanteric, total femoral Z-scores, and femoral Ward's region T-scores of the treatment group were lower than the median T- and Z-scores of the control group (p < 0.05). Of the treatment groups, the femoral neck, trochanteric and intertrochanteric T- and Z-scores, total femoral T- and Z-scores, and femoral Ward's T- and Z-scores of the sertraline group were significantly lower than the BMD values measured at the identical regions in the paroxetine and citalopram groups (p < 0.05).There was a significant negative correlation between the duration of treatment and the BMD values. CONCLUSION: SSRI therapy in GAD was found to be related with decreased BMD values. Further randomized controlled studies are warranted to determine whether SSRI use is a risk factor for osteoporosis; such studies should investigate these factors by performing BMD assessments before treatment.


Assuntos
Densidade Óssea/efeitos dos fármacos , Osteoporose Pós-Menopausa/induzido quimicamente , Inibidores Seletivos de Recaptação de Serotonina/efeitos adversos , Idoso , Transtornos de Ansiedade/tratamento farmacológico , Estudos Transversais , Feminino , Fêmur/fisiopatologia , Humanos , Vértebras Lombares/fisiopatologia , Pessoa de Meia-Idade , Osteoporose Pós-Menopausa/fisiopatologia , Escalas de Graduação Psiquiátrica , Inibidores Seletivos de Recaptação de Serotonina/farmacologia , Inibidores Seletivos de Recaptação de Serotonina/uso terapêutico
5.
Appl Radiat Isot ; 206: 111197, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38271853

RESUMO

Development of non-destructive analysis systems at the R&D beamline of the Proton Accelerator Facility of the Turkish Energy, Nuclear and Minerals Research Agency (TENMAK-PAF) is described in this work. The proton beam from the cyclotron with energy between 15-30 MeV and current between 0.1 µA-1.2 mA is modified with several components and subsystems to be suitable for the application of non-destructive analysis methods. Certified reference materials (CRM) and samples with different properties were irradiated under vacuum in the irradiation chamber with the new system. Particle Induced X-ray Emission (PIXE) and Particle Induced Gamma ray Emission (PIGE) spectra of these samples were obtained with appropriate radiation detectors and measurement systems. The results of PIXE analyses and X-ray fluorescence (XRF) spectrometry were compared. PIXE and PIGE results are in good agreement with the certified values for the CRMs. This work constitutes the first reported application of non-destructive ion beam analysis methods in TENMAK-PAF and in Türkiye.

6.
Aust Dent J ; 69(3): 175-181, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-38358069

RESUMO

AIM: The aim of the study was to compare serum ferritin and iron levels and periodontal status in pre- and post-menopausal female patients. MATERIALS AND METHODS: A total of 108 systemically healthy patients were included in the study, 63 patients in the pre-menopause group and 45 patients in the post-menopause group. The periodontal diagnosis was made according to the new periodontal disease classification of the American Academy of Periodontology and the European Federation of Periodontology Serum Iron (µg/dL) and Serum Ferritin (ng/mL) values were analysed in patients divided into groups according to menopausal status and periodontal status. RESULT: The mean ferritin in pre-menopausal women (34.96 ± 27.87 ng/mL) was lower than the mean ferritin in post-menopausal women (64.24 ± 36.05 ng/mL), and this difference was found to be statistically significant (P<0.001). There was no statistically significant difference between the averages of iron and ferritin according to periodontal diagnosis in pre-menopausal women (P = 0.200 and P = 0.858). A statistically significant difference was found between serum ferritin averages according to periodontal diagnosis in post-menopausal women (P < 0.001). Serum ferritin at % Interdental bone loss = 0 in Post-M was 33.93 ± 8.65 ng/mL; 47.51 ± 16.17 ng/mL in Stage 1 periodontitis; 72.66 ± 18.12 ng/mL in Stage 2 periodontitis; It was found to be 87.4 ± 47.1 ng/mL in Stage 3-4 periodontitis. CONCLUSION: Serum ferritin values might vary depending on the presence or severity of periodontitis in post-menopausal women.


Assuntos
Ferritinas , Gengivite , Ferro , Índice Periodontal , Periodontite , Pós-Menopausa , Pré-Menopausa , Humanos , Feminino , Ferritinas/sangue , Pós-Menopausa/sangue , Ferro/sangue , Pré-Menopausa/sangue , Gengivite/sangue , Pessoa de Meia-Idade , Adulto , Periodontite/sangue , Perda do Osso Alveolar/sangue , Perda do Osso Alveolar/classificação
7.
Eur Rev Med Pharmacol Sci ; 28(6): 2538-2549, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38567613

RESUMO

OBJECTIVE: In the present study, the protective effects of adenosine triphosphate (ATP), Benidipine, and Lacidipine on potential kidney damage induced by 5-fluorouracil (5-FU) were investigated in rats. MATERIALS AND METHODS: Totally 48 rats were divided into 8 groups: healthy (HG), 5-FU (FUG), ATP+5-FU (AFU), Benidipine+5-FU (BFU), Lacidipine+5-FU (LFU), ATP+Benidipine+5-FU (ABFU), ATP+Lacidipine+5-FU (ALFU) and Benidipine+Lacidipine+5-FU (BLFU). In a 10-day period, ATP (4 mg/kg) was administered intraperitoneally, and Benidipine (4 mg/kg) and Lacidipine (4 mg/kg) were administered orally once a day. On days 1, 3, and 5, 5-FU (100 mg/kg) was administered intraperitoneally one hour after the drug was administered. Afterward, the rats were euthanized, and kidney tissues were removed. An analysis of malondialdehyde, total glutathione, superoxide dismutase, and catalase was performed on tissues, as well as a histopathological examination. A creatinine and blood urea nitrogen analysis were performed on blood samples. RESULTS: It was revealed that 5-FU decreased the amount of total glutathione, superoxide dismutase, and catalase activities in rat kidney tissues and increased malondialdehyde. Further, increased serum creatinine and blood urea nitrogen levels, as well as histopathological examination of kidney tissues, were found in the 5-FU group. ATP+Benidipine and ATP treatments were the most effective in preventing both biochemical and histopathological changes induced by 5-FU. A treatment with Benidipine improved biochemical and histopathologic data, but not to the same extent as a treatment with ATP+Benidipine and ATP. As a result of Lacidipine+ATP combination, 5-FU-induced biochemical changes in kidney tissue were partially inhibited, but the degree of histopathologic damage remained unchanged. Neither Benidipine+Lacidipine nor Lacidipine showed a protective effect on both biochemical changes and histopathologic damage. CONCLUSIONS: It may be possible to prevent nephrotoxicity by adding ATP + Benidipine or ATP to 5-FU treatment.


Assuntos
Di-Hidropiridinas , Fluoruracila , Nefropatias , Ratos , Animais , Fluoruracila/efeitos adversos , Rim/patologia , Catalase , Trifosfato de Adenosina , Nefropatias/induzido quimicamente , Nefropatias/tratamento farmacológico , Nefropatias/prevenção & controle , Glutationa , Superóxido Dismutase , Malondialdeído
8.
J Colloid Interface Sci ; 617: 409-421, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-35279576

RESUMO

This study presents a versatile method to synthesize stimuli-responsive microgels with supramolecular cross-links exhibiting tunable size and shape via droplet-based microfluidics. The natural polyphenol tannic acid (TA) is used to cross-link poly(N-vinylcaprolactam) (PVCL) chains in aqueous droplets by the formation of hydrogen bonds and hydrophobic interactions between the phenolic groups of TA and the carbonyl group and the hydrophobic segments of lactam ring of PVCL chains. The obtained microgels exhibit diameters in the range of 130-150µm in swollen state in aqueous solution. Synthesized microgels exhibit pH-responsive behavior: at low pH microgels deswell and shrink due to the protonation of phenolic groups and enhanced hydrophobic interactions; at high pH microgels swell and disintegrate due to the deprotonation of phenolic groups and destruction of hydrogen bonds with PVCL chains. Additionally, we present supramacromolecular microgels in cylindrical shape with different aspect ratios using a new design of microfluidic chip by varying flow rates at high concentration of the prepolymerized precursor combined with rapid pH-triggered on-chip gelation. Furthermore, developed synthesis methodology allows on-chip encapsulation of colloidal objects into large supramacromolecular microgels during the cross-linking step. The complete and fast release of objects by pH-triggered degradation indicates that the pH-responsive supramacromolecular microgels can be used for controlled loading/release of various payloads, like probiotics. Moreover, cell studies of L929 fibroblast clearly show the biocompatibility of the microgels.


Assuntos
Microgéis , Hidrogéis/química , Concentração de Íons de Hidrogênio , Microfluídica/métodos , Taninos/química
9.
Eur Rev Med Pharmacol Sci ; 26(19): 7195-7203, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-36263529

RESUMO

OBJECTIVE: The aim of our study was to investigate the protective effect of taxifolin on ovarian damage and reproductive dysfunction created by cisplatin administration. MATERIALS AND METHODS: A total of 36 albino Wistar female adult rats were equally divided into 3 groups as cisplatin administered only (CIS), taxifolin+cisplatin (T+C) and healthy control group (HG). Taxifolin 50 mg/kg was administered orally by gavage in the T+C (n=12) group. In the HG (n=12) and CIS (n=12) groups, the same volume of distilled water as a solvent was orally administered. One hour after administration of taxifolin or distilled water, animals in the T+C and CIS groups were injected with cisplatin at a dose of 2.5 mg/kg intraperitoneally. This procedure was repeated once a day for 14 days. Six animals from each group were sacrificed on day 15, and their ovaries were removed for histopathological and biochemical analysis. Ovarian tissue malondialdehyde (MDA), total Glutathione (tGSH), Nuclear Factor-Kappa B (NF-kB), Tumor Necrosis Factor-α (TNF-α), Interleukin 1 beta (IL-1ß), and Interleukin-6 (IL-6) levels were measured. The remaining animals (n=6 in each group) were kept in the laboratory with mature male rats for two months to breed. RESULTS: CIS administration led to an increase in inflammatory molecules and membrane lipid peroxidation products, and decreased the synthesis of antioxidant molecules. Compared to the CIS group, the ovarian tissue MDA, NF-kB, TNF-α, IL-1ß and IL-6 levels were found to be significantly decreased in the T+C group (p<0.001 for all comparisons). On the other hand, the tGSH levels of the T+C group were significantly higher than the CIS group (p<0.001). Milder ovarian necrosis, fibrosis and follicle damage were detected in animals which were given taxifolin. Four out of the six rats (67%) treated with taxifolin gave birth within 27 days. CONCLUSIONS: We demonstrated, for the first time, that taxifolin ameliorates cisplatin-induced ovarian injury by decreasing MDA and proinflammatory cytokines and increasing the antioxidant enzyme. The fact that more than half of the animals receiving taxifolin became pregnant suggests that the cytoprotective effect of taxifolin is strong enough to preserve fertility.


Assuntos
Cisplatino , Fármacos para a Fertilidade , Masculino , Feminino , Ratos , Animais , Cisplatino/toxicidade , Antioxidantes/metabolismo , Interleucina-1beta/metabolismo , Fator de Necrose Tumoral alfa/metabolismo , Interleucina-6/farmacologia , Ovário/metabolismo , NF-kappa B/metabolismo , Fármacos para a Fertilidade/farmacologia , Estresse Oxidativo , Malondialdeído , Glutationa/metabolismo , Ratos Wistar , Citocinas , Solventes/farmacologia , Fertilidade , Água
10.
Braz J Biol ; 82: e237849, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33787734

RESUMO

Meriones dahli (Shidlovsky, 1962) was previously accepted to be a subspecies of M. meridianus (Pallas, 1773). However, it was later suggested that they are geographically isolated from each other. Although hybridological studies and differences in certain external characteristics support the idea that M. dahli is a separate species, there are still doubts on its species status, and the exact range of its distribution is not known. In this paper, we provide some taxonomic information about the species, and compare these with the information given in previous studies. We argue that some differences exist among Armenian population regarding external measurements. Recent studies indicate that M. dahli is currently only distributed in Turkey, as an endemic mammal species. We provide predictions about the distribution of M. dahli, and report the estimated population size to its maximum value. Food preference studies for this species, conducted under laboratory conditions, are also introduced for the first time. We discuss the ecological data obtained from field studies, and emphasize that the habitat of M. dahli is about to disappear. Consequently, the protection status of this species should urgently be changed to the CR category and conservation studies must be carried out immediately.


Assuntos
Dieta , Ecossistema , Animais , Gerbillinae , Densidade Demográfica
11.
J Chem Phys ; 133(12): 124502, 2010 Sep 28.
Artigo em Inglês | MEDLINE | ID: mdl-20886945

RESUMO

Positron annihilation lifetime spectroscopy (PALS) is used to study the ionic liquid 1-methyl-3-propylimidazolium bis(trifluoromethylsulfonyl)imide [C(3)MIM][NTf(2)] in the temperature range between 150 and 320 K. The positron decay spectra are analyzed using the routine LifeTime-9.0 and the size distribution of local free volumes (subnanometer-size holes) is calculated. This distribution is in good agreement with Fürth's classical hole theory of liquids when taking into account Fürth's hole coalescence hypothesis. During cooling, the liquid sample remains in a supercooled, amorphous state and shows the glass transition in the ortho-positronium (o-Ps) lifetime at 187 K. The mean hole volume varies between 70 Å(3) at 150 K and 250 Å(3) at 265-300 K. From a comparison with the macroscopic volume, the hole density is estimated to be constant at 0.20×10(21) g(-1) corresponding to 0.30 nm(-3) at 265 K. The hole free volume fraction varies from 0.023 at 185 K to 0.073 at T(m)+12 K=265 K and can be estimated to be 0.17 at 430 K. It is shown that the viscosity follows perfectly the Cohen-Turnbull free volume theory when using the free volume determined here. The heating run clearly shows crystallization at 200 K by an abrupt decrease in the mean <τ(3)> and standard deviation σ(3) of the o-Ps lifetime distribution and an increase in the o-Ps intensity I(3). The parameters of the second lifetime component <τ(2)> and σ(2) behave parallel to the o-Ps parameters, which also shows the positron's (e(+)) response to structural changes. During melting at 253 K, all lifetime parameters recover to the initial values of the liquid. An abrupt decrease in I(3) is attributed to the solvation of e(-) and e(+) particles. Different possible interpretations of the o-Ps lifetime in the crystalline state are briefly discussed.

12.
Cephalalgia ; 29(1): 68-75, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18771489

RESUMO

Migraine is more likely to be misdiagnosed in patients with comorbid diseases. Not only primary care physicians, but also specialists might misdiagnose it due to the lack of diagnostic criteria awareness. The ID migraine test is a reliable screening instrument that may facilitate and accelerate migraine recognition. This study aimed to compare the prevalence and characteristics of migraine in a large sample of patients admitted to clinics of ophthalmology (OC), ear, nose and throat diseases (ENTC) and neurology (NC), as well as to validate the use of the ID migraine test in OC and ENTC settings. This was a multicentre (11 cites) study of out-patients admitting either to NC, ENTC or OC of the study sites during five consecutive working days within 1 week. From each of the clinics, 100 patients were planned to be recruited. All recruited patients were interviewed and those having a headache complaint received an ID migraine test and were examined for headache diagnosis by a neurologist, blinded to the ID migraine test result. A total of 2625 subjects were recruited. Only 1.3% of OC patients and 5.4% of ENTC patients have been admitted with a primary complaint of headache, whereas the percentage of NC patients suffering from headache was 37.6%. Whereas 138 patients (19.3%) in OC, 154 (17.3%) in ENTC and 347 (34%) in NC were found to be ID migraine test positive, 149 patients (20.8%) in OC, 142 (16%) in ENTC and 338 (33.1%) in NC were diagnosed with migraine. The sensitivity, specificity, and positive and negative predictive ratios of the ID migraine test were found to be similar in all clinics. An important fraction of the patients admitted to NC, as well as to OC and ENTC, for headache and/or other complaints were found out to have migraine by means of a simple screening test. This study validated the ID migraine test as a sensitive and specific tool in OC and ENTC, encouraging its use as a screening instrument.


Assuntos
Instituições de Assistência Ambulatorial/estatística & dados numéricos , Transtornos de Enxaqueca/diagnóstico , Transtornos de Enxaqueca/epidemiologia , Neurologia/estatística & dados numéricos , Oftalmologia/estatística & dados numéricos , Otolaringologia/estatística & dados numéricos , Adulto , Feminino , Humanos , Masculino , Programas de Rastreamento/métodos , Pessoa de Meia-Idade , Prevalência
13.
Anaesthesia ; 64(9): 942-6, 2009 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-19686477

RESUMO

The objective of this study was to compare the block durations and haemodynamic effects associated with intrathecal levobupivacaine or bupivacaine in elderly patients undergoing transurethral prostate surgery. Eighty patients were prospectively randomised to receive plain 1.5 ml levobupivacaine 0.5% (group levobupivacaine) or 1.5 ml plain bupivacaine 0.5% (group bupivacaine) in combination with fentanyl 0.3 ml (15 microg) for spinal anaesthesia. The time to reach T10 and peak sensory block level, and to maximum motor block were significantly shorter in group bupivacaine compared to group levobupivacaine (p < 0.05). Peak sensory block level was also significantly higher in group bupivacaine. In group bupivacaine, mean arterial pressure was significantly lower than group levobupivacaine, starting from 10 min until 30 min after injection (p < 0.05). Hypotension and nausea were less common in group levobupivacaine than group bupivacaine (p < 0.05). Because of the better haemodynamic stability and fewer side-effects associated with levobupivacaine, it may be preferred for spinal anaesthesia in elderly patients.


Assuntos
Anestésicos Locais/farmacologia , Bupivacaína/farmacologia , Idoso , Raquianestesia/efeitos adversos , Raquianestesia/métodos , Anestésicos Locais/efeitos adversos , Pressão Sanguínea/efeitos dos fármacos , Bupivacaína/efeitos adversos , Bupivacaína/análogos & derivados , Fentanila/farmacologia , Frequência Cardíaca/efeitos dos fármacos , Humanos , Hipotensão/induzido quimicamente , Levobupivacaína , Masculino , Pessoa de Meia-Idade , Movimento/efeitos dos fármacos , Náusea e Vômito Pós-Operatórios/induzido quimicamente , Estudos Prospectivos , Sensação/efeitos dos fármacos , Ressecção Transuretral da Próstata
14.
Br J Dermatol ; 159(4): 834-8, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18652587

RESUMO

BACKGROUND: Atopic dermatitis (AD) is a chronic dermatitis characterized by intense itching and excessive skin dryness. The factor most commonly blamed for the pathogenesis of skin dryness in the disease is impaired barrier function of the stratum corneum. However, there are findings indicating that the autonomic nervous system, and the sympathetic nervous system in particular, is affected negatively in AD, and thus, autonomic dysfunction can be an important factor leading to skin dryness. OBJECTIVE: In this study we aimed to evaluate the functioning of the autonomic nervous system electrophysiologically using R-R interval variation (RRIV) and the sympathetic skin response (SSR) in patients with AD, and to examine whether there is an underlying autonomic nervous system dysfunction. PATIENTS AND METHODS: The study registered a total of 38 (12 males and 26 females) patients with AD, of whom 24 had active and 14 inactive disease, and 20 (10 males and 10 females) healthy control subjects. RRIV was used in our study as the electrophysiological test to evaluate the parasympathetic system. The SSR method, which is a noninvasive electrophysiological test with a significant role in evaluating the sudomotor activity of skin, as well as that of the unmyelinated fibres that take a part in this activity, was employed to assess the sympathetic nervous system. RESULTS: Our study revealed a significantly prolonged SSR latency and amplitude of the upper extremity in the patient group, relative to the control group (P < 0.05). When the group with active skin lesions was compared with the control group, the former was found to have prolonged SSR latency and amplitude in the upper extremity. The prolongation in SSR latency of the upper extremity was statistically significant (P < 0.05), while the prolongation in amplitude was not (P = 0.5). An evaluation of RRIV results did not show a significant difference between the patient and control groups. CONCLUSIONS: These findings demonstrate that the sudomotor activity controlled by the sympathetic nervous system, as well as unmyelinated fibres that play a role in this activity are affected in patients with AD. We think that the involvement of sudomotor activity may be one of the causes that leads to dysfunction in sweat glands and skin dryness.


Assuntos
Sistema Nervoso Autônomo/fisiopatologia , Dermatite Atópica/etiologia , Resposta Galvânica da Pele/fisiologia , Pele/inervação , Adolescente , Estudos de Casos e Controles , Criança , Dermatite Atópica/fisiopatologia , Estimulação Elétrica/métodos , Feminino , Humanos , Masculino , Tempo de Reação/fisiologia
15.
Eur Phys J E Soft Matter ; 27(3): 261-73, 2008 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18972143

RESUMO

We present a comprehensive study of the concentration-induced growth of nonionic wormlike micelles in dilute solutions, below the overlap concentration, where we combine static and dynamic light scattering and NMR self-diffusion. The data are analyzed in detail in terms of the number-averaged contour length, assuming an exponential size distribution, as predicted by theory, and that the micellar flexibility can be described by the wormlike chain model with a certain persistence length. A very good agreement between the different experimental methods is obtained. The number-averaged contour length increases with increasing micelle volume fraction. The data are consistent with a power law, where the power law exponent is in the range 0.5-0.8, depending on the system. The result is in reasonable agreement with the theory of living polymers.


Assuntos
Micelas , Modelos Moleculares , Éteres/química , Espectroscopia de Ressonância Magnética , Polietilenoglicóis/química , Água/química
16.
Eur J Gynaecol Oncol ; 29(6): 659-60, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-19115701

RESUMO

A case of a rarely occurring ovarian tumor, sclerosing stromal tumor of the ovary, in an 11-year-old girl treated laparoscopically is described.


Assuntos
Neoplasias Ovarianas/patologia , Células Estromais/patologia , Criança , Feminino , Humanos , Esclerose/patologia
17.
Neth Heart J ; 15(7-8): 260-2, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17923882

RESUMO

Takayasu's arteritis is a chronic vasculitis of unknown aetiology involving the aorta and its main branches, the pulmonary and coronary tree. Women are affected more often than men (80 to 90% of the cases) with an age onset between 10 and 40 years. This case report demonstrates the limitations of exercise testing and stress echocardiography in diagnosing the extent of coronary artery disease in patients with inflammatory disease in the left main stem coronary artery. (Neth Heart J 2007;15:260-2.).

18.
Braz. j. biol ; 82: 1-7, 2022. map, ilus, tab
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1468431

RESUMO

Meriones dahli (Shidlovsky, 1962) was previously accepted to be a subspecies of M. meridianus (Pallas, 1773). However, it was later suggested that they are geographically isolated from each other. Although hybridological studies and differences in certain external characteristics support the idea that M. dahli is a separate species, there are still doubts on its species status, and the exact range of its distribution is not known. In this paper, we provide some taxonomic information about the species, and compare these with the information given in previous studies. We argue that some differences exist among Armenian population regarding external measurements. Recent studies indicate that M. dahli is currently only distributed in Turkey, as an endemic mammal species. We provide predictions about the distribution of M. dahli, and report the estimated population size to its maximum value. Food preference studies for this species, conducted under laboratory conditions, are also introduced for the first time. We discuss the ecological data obtained from field studies, and emphasize that the habitat of M. dahli is about to disappear. Consequently, the protection status of this species should urgently be changed to the CR category and conservation studies must be carried out immediately.


Meriones dahli (Shidlovsky, 1962) foi previamente aceito como uma subespécie de M. meridianus (Pallas, 1773). No entanto, mais tarde, foi sugerido que eles estão geograficamente isolados um do outro. Embora estudos hibridológicos e diferenças em certas características externas apoiem a ideia de que M. dahli é uma espécie separada, ainda há dúvidas sobre o status de sua espécie, e a extensão exata de sua distribuição não é conhecida. Neste artigo, fornecemos algumas informações taxonômicas sobre as espécies e as comparamos com as informações fornecidas em estudos anteriores. Argumentamos que existem algumas diferenças entre a espécie armênia em relação às medidas externas. Estudos recentes indicam que M. dahli está atualmente distribuído apenas na Turquia como uma espécie endêmica de mamífero. Fornecemos previsões sobre a distribuição de M. dahli e relatamos o tamanho estimado da população em seu valor máximo. Estudos de preferência alimentar para essa espécie, conduzidos em condições de laboratório, também são introduzidos pela primeira vez. Discutimos sobre os dados ecológicos obtidos em estudos de campo e enfatizamos que o habitat de M. dahli está prestes a desaparecer. Consequentemente, o status de proteção dessa espécie deve ser alterado com urgência para a categoria CR, e estudos de conservação devem ser realizados imediatamente.


Assuntos
Animais , Camundongos , Crescimento Demográfico , Especificidade da Espécie , Espécies em Perigo de Extinção , Gerbillinae/classificação , Grupos de População Animal
19.
Braz. j. biol ; 82: e237849, 2022. tab, graf
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1153487

RESUMO

Meriones dahli (Shidlovsky, 1962) was previously accepted to be a subspecies of M. meridianus (Pallas, 1773). However, it was later suggested that they are geographically isolated from each other. Although hybridological studies and differences in certain external characteristics support the idea that M. dahli is a separate species, there are still doubts on its species status, and the exact range of its distribution is not known. In this paper, we provide some taxonomic information about the species, and compare these with the information given in previous studies. We argue that some differences exist among Armenian population regarding external measurements. Recent studies indicate that M. dahli is currently only distributed in Turkey, as an endemic mammal species. We provide predictions about the distribution of M. dahli, and report the estimated population size to its maximum value. Food preference studies for this species, conducted under laboratory conditions, are also introduced for the first time. We discuss the ecological data obtained from field studies, and emphasize that the habitat of M. dahli is about to disappear. Consequently, the protection status of this species should urgently be changed to the CR category and conservation studies must be carried out immediately.


Meriones dahli (Shidlovsky, 1962) foi previamente aceito como uma subespécie de M. meridianus (Pallas, 1773). No entanto, mais tarde, foi sugerido que eles estão geograficamente isolados um do outro. Embora estudos hibridológicos e diferenças em certas características externas apoiem a ideia de que M. dahli é uma espécie separada, ainda há dúvidas sobre o status de sua espécie, e a extensão exata de sua distribuição não é conhecida. Neste artigo, fornecemos algumas informações taxonômicas sobre as espécies e as comparamos com as informações fornecidas em estudos anteriores. Argumentamos que existem algumas diferenças entre a espécie armênia em relação às medidas externas. Estudos recentes indicam que M. dahli está atualmente distribuído apenas na Turquia como uma espécie endêmica de mamífero. Fornecemos previsões sobre a distribuição de M. dahli e relatamos o tamanho estimado da população em seu valor máximo. Estudos de preferência alimentar para essa espécie, conduzidos em condições de laboratório, também são introduzidos pela primeira vez. Discutimos sobre os dados ecológicos obtidos em estudos de campo e enfatizamos que o habitat de M. dahli está prestes a desaparecer. Consequentemente, o status de proteção dessa espécie deve ser alterado com urgência para a categoria CR, e estudos de conservação devem ser realizados imediatamente.


Assuntos
Animais , Ecossistema , Dieta , Gerbillinae , Densidade Demográfica
20.
J Orthop Surg (Hong Kong) ; 14(2): 133-7, 2006 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-16914775

RESUMO

PURPOSE: To investigate the effect of extracorporeal shock wave treatment (ESWT) on bony union using volume analysis of the callus mass by computed tomography and histology. METHODS: Both radii of 13 rabbits were osteotomised and a defective bony nonunion created by placing a polyethylene pad between the osteotomy site for 40 days. Nonunion was confirmed by radiography using Lane-Sandhu criteria. ESWT (14 kW, 0.46 mJ/mm(2), 1000 shock waves) was applied to the right radius of the rabbits. The left radius served as a control. Five rabbits were killed 4 weeks after ESWT (group 1) and 8 after 6 weeks (group 2). Volume analysis of the callus mass was performed using computed tomography and the bone healing process was assessed by histology. RESULTS: In group 1, callus volume on the treated side was invariably greater than that on the control side; the difference being statistically significant (p=0.032). In group 2, the callus volume of the treated side was greater than that of the control side, except in rabbits 4 and 9. Only after excluding the findings from the latter did the difference attain statistical significance (p=0.020). Histology confirmed that the bone-healing process was faster in the treated side. CONCLUSION: ESWT enhanced the bone-healing process by increasing both volume and speed of callus formation.


Assuntos
Fraturas não Consolidadas/terapia , Ondas de Choque de Alta Energia/uso terapêutico , Fraturas do Rádio/terapia , Animais , Calo Ósseo , Consolidação da Fratura , Coelhos
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA