Detalhe da pesquisa
1.
Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival.
Cell
; 162(6): 1365-78, 2015 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26359988
2.
Developmental synaptic regulator, TWEAK/Fn14 signaling, is a determinant of synaptic function in models of stroke and neurodegeneration.
Proc Natl Acad Sci U S A
; 118(6)2021 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33526652
3.
Proteomic Characterization of the Dynamics of Ischemic Stroke in Mice.
J Proteome Res
; 20(7): 3689-3700, 2021 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34085531
4.
Investigating small molecules to inhibit germinal center kinase-like kinase (GLK/MAP4K3) upstream of PKCθ phosphorylation: Potential therapy to modulate T cell dependent immunity.
Bioorg Med Chem Lett
; 28(10): 1964-1971, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29636220
5.
A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and Infection.
J Immunol
; 197(1): 377-86, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27233964
6.
TWEAK/Fn14 axis: the current paradigm of tissue injury-inducible function in the midst of complexities.
Semin Immunol
; 26(3): 229-36, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24636536
7.
Tweak regulates astrogliosis, microgliosis and skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis.
Hum Mol Genet
; 24(12): 3440-56, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25765661
8.
Repeated administration of dapirolizumab pegol in a randomised phase I study is well tolerated and accompanied by improvements in several composite measures of systemic lupus erythematosus disease activity and changes in whole blood transcriptomic profiles.
Ann Rheum Dis
; 76(11): 1837-1844, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28780512
9.
Alterations in urinary collagen peptides in lupus nephritis subjects correlate with renal dysfunction and renal histopathology.
Nephrol Dial Transplant
; 32(9): 1468-1477, 2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28339802
10.
Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation.
J Pathol
; 239(1): 109-21, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26924336
11.
TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease.
J Am Soc Nephrol
; 27(12): 3639-3652, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27026366
12.
Deficiency of fibroblast growth factor-inducible 14 (Fn14) preserves the filtration barrier and ameliorates lupus nephritis.
J Am Soc Nephrol
; 26(5): 1053-70, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25270074
13.
Role of Fn14 in acute alcoholic steatohepatitis in mice.
Am J Physiol Gastrointest Liver Physiol
; 308(4): G325-34, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25524063
14.
TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice.
J Autoimmun
; 60: 40-50, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25911200
15.
Regulatory circuitry of TWEAK-Fn14 system and PGC-1α in skeletal muscle atrophy program.
FASEB J
; 28(3): 1398-411, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24327607
16.
TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses.
Immunol Rev
; 244(1): 99-114, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22017434
17.
Genetic deletion or TWEAK blocking antibody administration reduce atherosclerosis and enhance plaque stability in mice.
J Cell Mol Med
; 18(4): 721-34, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24479820
18.
Fn14 in podocytes and proteinuric kidney disease.
Biochim Biophys Acta
; 1832(12): 2232-43, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23999007
19.
TNF-related weak inducer of apoptosis (TWEAK) promotes kidney fibrosis and Ras-dependent proliferation of cultured renal fibroblast.
Biochim Biophys Acta
; 1832(10): 1744-55, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23748045
20.
The TWEAK-Fn14 dyad is involved in age-associated pathological changes in skeletal muscle.
Biochem Biophys Res Commun
; 446(4): 1219-1224, 2014 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24680686