Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Actives from MMV Open Access Boxes? A suggested way forward.

Samby, Kirandeep; Willis, Paul A; Burrows, Jeremy N; Laleu, Benoît; Webborn, Peter J H.

PLoS Pathog ; 17(4): e1009384, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33886696

2.

Optimized Pyridazinone Nutrient Channel Inhibitors Are Potent and Specific Antimalarial Leads.

Butler, Michelle M; Waidyarachchi, Samanthi L; Shao, Jinfeng; Nguyen, Son T; Ding, Xiaoyuan; Cardinale, Steven C; Morin, Lucas R; Kwasny, Steven M; Ito, Mai; Gezelle, Jeanine; Jiménez-Díaz, María B; Angulo-Barturen, Iñigo; Jacobs, Robert T; Burrows, Jeremy N; Aron, Zachary D; Bowlin, Terry L; Desai, Sanjay A.

Mol Pharmacol ; 102(3): 172-182, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35798366

3.

Estimating local need for mental healthcare to inform fair resource allocation in the NHS in England: cross-sectional analysis of national administrative data linked at person level.

Anselmi, Laura; Everton, Anna; Shaw, Robert; Suzuki, Wataru; Burrows, Jeremy; Weir, Richard; Tatarek-Gintowt, Roman; Sutton, Matt; Lorrimer, Stephen.

Br J Psychiatry ; 216(6): 338-344, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-31391127

4.

An in vitro toolbox to accelerate anti-malarial drug discovery and development.

Charman, Susan A; Andreu, Alice; Barker, Helena; Blundell, Scott; Campbell, Anna; Campbell, Michael; Chen, Gong; Chiu, Francis C K; Crighton, Elly; Katneni, Kasiram; Morizzi, Julia; Patil, Rahul; Pham, Thao; Ryan, Eileen; Saunders, Jessica; Shackleford, David M; White, Karen L; Almond, Lisa; Dickins, Maurice; Smith, Dennis A; Moehrle, Joerg J; Burrows, Jeremy N; Abla, Nada.

Malar J ; 19(1): 1, 2020 Jan 02.

Artigo em Inglês | MEDLINE | ID: mdl-31898492

5.

Partnering to fight malaria in India: Past, present and future.

Samby, Kirandeep; Ramachandruni, Hanu; Banerji, Jaya; Burrows, Jeremy N; Daumerie, Penny Grewal; Hooft van Huijsduijnen, Rob A M; Duparc, Stephan; Wells, Timothy N C.

J Vector Borne Dis ; 56(1): 15-24, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31070161

6.

A discovery and development roadmap for new endectocidal transmission-blocking agents in malaria.

Burrows, Jeremy; Slater, Hannah; Macintyre, Fiona; Rees, Sarah; Thomas, Anna; Okumu, Fredros; Hooft van Huijsduijnen, Rob; Duparc, Stephan; Wells, Timothy N C.

Malar J ; 17(1): 462, 2018 Dec 10.

Artigo em Inglês | MEDLINE | ID: mdl-30526594

7.

Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria.

Macintyre, Fiona; Ramachandruni, Hanu; Burrows, Jeremy N; Holm, René; Thomas, Anna; Möhrle, Jörg J; Duparc, Stephan; Hooft van Huijsduijnen, Rob; Greenwood, Brian; Gutteridge, Winston E; Wells, Timothy N C; Kaszubska, Wiweka.

Malar J ; 17(1): 402, 2018 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-30384848

8.

New developments in anti-malarial target candidate and product profiles.

Burrows, Jeremy N; Duparc, Stephan; Gutteridge, Winston E; Hooft van Huijsduijnen, Rob; Kaszubska, Wiweka; Macintyre, Fiona; Mazzuri, Sébastien; Möhrle, Jörg J; Wells, Timothy N C.

Malar J ; 16(1): 26, 2017 01 13.

Artigo em Inglês | MEDLINE | ID: mdl-28086874

9.

Shared Consensus Machine Learning Models for Predicting Blood Stage Malaria Inhibition.

Verras, Andreas; Waller, Chris L; Gedeck, Peter; Green, Darren V S; Kogej, Thierry; Raichurkar, Anandkumar; Panda, Manoranjan; Shelat, Anang A; Clark, Julie; Guy, R Kiplin; Papadatos, George; Burrows, Jeremy.

J Chem Inf Model ; 57(3): 445-453, 2017 03 27.

Artigo em Inglês | MEDLINE | ID: mdl-28257198

10.

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.

Le Bihan, Amélie; de Kanter, Ruben; Angulo-Barturen, Iñigo; Binkert, Christoph; Boss, Christoph; Brun, Reto; Brunner, Ralf; Buchmann, Stephan; Burrows, Jeremy; Dechering, Koen J; Delves, Michael; Ewerling, Sonja; Ferrer, Santiago; Fischli, Christoph; Gamo-Benito, Francisco Javier; Gnädig, Nina F; Heidmann, Bibia; Jiménez-Díaz, María Belén; Leroy, Didier; Martínez, Maria Santos; Meyer, Solange; Moehrle, Joerg J; Ng, Caroline L; Noviyanti, Rintis; Ruecker, Andrea; Sanz, Laura María; Sauerwein, Robert W; Scheurer, Christian; Schleiferboeck, Sarah; Sinden, Robert; Snyder, Christopher; Straimer, Judith; Wirjanata, Grennady; Marfurt, Jutta; Price, Ric N; Weller, Thomas; Fischli, Walter; Fidock, David A; Clozel, Martine; Wittlin, Sergio.

PLoS Med ; 13(10): e1002138, 2016 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-27701420

11.

Microbiology: Malaria runs rings round artemisinin.

Burrows, Jeremy.

Nature ; 520(7549): 628-30, 2015 Apr 30.

Artigo em Inglês | MEDLINE | ID: mdl-25874678

12.

Subtle changes in endochin-like quinolone structure alter the site of inhibition within the cytochrome bc1 complex of Plasmodium falciparum.

Stickles, Allison M; de Almeida, Mariana Justino; Morrisey, Joanne M; Sheridan, Kayla A; Forquer, Isaac P; Nilsen, Aaron; Winter, Rolf W; Burrows, Jeremy N; Fidock, David A; Vaidya, Akhil B; Riscoe, Michael K.

Antimicrob Agents Chemother ; 59(4): 1977-82, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25605352

13.

ELQ-300 prodrugs for enhanced delivery and single-dose cure of malaria.

Miley, Galen P; Pou, Sovitj; Winter, Rolf; Nilsen, Aaron; Li, Yuexin; Kelly, Jane X; Stickles, Allison M; Mather, Michael W; Forquer, Isaac P; Pershing, April M; White, Karen; Shackleford, David; Saunders, Jessica; Chen, Gong; Ting, Li-Min; Kim, Kami; Zakharov, Lev N; Donini, Cristina; Burrows, Jeremy N; Vaidya, Akhil B; Charman, Susan A; Riscoe, Michael K.

Antimicrob Agents Chemother ; 59(9): 5555-60, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-26124159

14.

Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis.

Doggett, J Stone; Nilsen, Aaron; Forquer, Isaac; Wegmann, Keith W; Jones-Brando, Lorraine; Yolken, Robert H; Bordón, Claudia; Charman, Susan A; Katneni, Kasiram; Schultz, Tracey; Burrows, Jeremy N; Hinrichs, David J; Meunier, Brigitte; Carruthers, Vern B; Riscoe, Michael K.

Proc Natl Acad Sci U S A ; 109(39): 15936-41, 2012 Sep 25.

Artigo em Inglês | MEDLINE | ID: mdl-23019377

15.

Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum.

Avery, Vicky M; Bashyam, Sridevi; Burrows, Jeremy N; Duffy, Sandra; Papadatos, George; Puthukkuti, Shyni; Sambandan, Yuvaraj; Singh, Shivendra; Spangenberg, Thomas; Waterson, David; Willis, Paul.

Malar J ; 13: 190, 2014 May 27.

Artigo em Inglês | MEDLINE | ID: mdl-24886460

16.

Antimalarial drug discovery - the path towards eradication.

Burrows, Jeremy N; Burlot, Emilie; Campo, Brice; Cherbuin, Stephanie; Jeanneret, Sarah; Leroy, Didier; Spangenberg, Thomas; Waterson, David; Wells, Timothy Nc; Willis, Paul.

Parasitology ; 141(1): 128-39, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-23863111

17.

Combating antimicrobial resistance in malaria, HIV and tuberculosis.

Duffey, Maëlle; Shafer, Robert W; Timm, Juliano; Burrows, Jeremy N; Fotouhi, Nader; Cockett, Mark; Leroy, Didier.

Nat Rev Drug Discov ; 2024 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-38750260

18.

Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum.

Pires, Camilla Valente; Cassandra, Debora; Xu, Shulin; Laleu, Benoit; Burrows, Jeremy N; Adams, John H.

mBio ; 15(3): e0316923, 2024 Mar 13.

Artigo em Inglês | MEDLINE | ID: mdl-38323831

19.

Protein target similarity is positive predictor of in vitro antipathogenic activity: a drug repurposing strategy for Plasmodium falciparum.

Mogire, Reagan M; Miruka, Silviane A; Juma, Dennis W; McNamara, Case W; Andagalu, Ben; Burrows, Jeremy N; Chenu, Elodie; Duffy, James; Ogutu, Bernhards R; Akala, Hoseah M.

J Cheminform ; 16(1): 63, 2024 May 30.

Artigo em Inglês | MEDLINE | ID: mdl-38831351

20.

Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.

Xie, Stanley C; Wang, Yinuo; Morton, Craig J; Metcalfe, Riley D; Dogovski, Con; Pasaje, Charisse Flerida A; Dunn, Elyse; Luth, Madeline R; Kumpornsin, Krittikorn; Istvan, Eva S; Park, Joon Sung; Fairhurst, Kate J; Ketprasit, Nutpakal; Yeo, Tomas; Yildirim, Okan; Bhebhe, Mathamsanqa N; Klug, Dana M; Rutledge, Peter J; Godoy, Luiz C; Dey, Sumanta; De Souza, Mariana Laureano; Siqueira-Neto, Jair L; Du, Yawei; Puhalovich, Tanya; Amini, Mona; Shami, Gerry; Loesbanluechai, Duangkamon; Nie, Shuai; Williamson, Nicholas; Jana, Gouranga P; Maity, Bikash C; Thomson, Patrick; Foley, Thomas; Tan, Derek S; Niles, Jacquin C; Han, Byung Woo; Goldberg, Daniel E; Burrows, Jeremy; Fidock, David A; Lee, Marcus C S; Winzeler, Elizabeth A; Griffin, Michael D W; Todd, Matthew H; Tilley, Leann.

Nat Commun ; 15(1): 937, 2024 Jan 31.

Artigo em Inglês | MEDLINE | ID: mdl-38297033

BVS Doenças Infecciosas e Parasitárias

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar: