Detalhe da pesquisa
1.
DNA damage and transcription stress.
Mol Cell
; 84(1): 70-79, 2024 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38103560
2.
APE1-dependent base excision repair of DNA photodimers in human cells.
Mol Cell
; 83(20): 3669-3678.e7, 2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37816354
3.
XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.
Mol Cell
; 81(14): 3018-3030.e5, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34102106
4.
Causes and consequences of DNA single-strand breaks.
Trends Biochem Sci
; 49(1): 68-78, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38040599
5.
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity.
EMBO J
; 42(18): e113190, 2023 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37492888
6.
Neuronal enhancers are hotspots for DNA single-strand break repair.
Nature
; 593(7859): 440-444, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33767446
7.
Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
Mol Cell
; 75(2): 252-266.e8, 2019 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31202577
8.
The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication.
Mol Cell
; 71(2): 319-331.e3, 2018 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29983321
9.
Inactivating TDP2 missense mutation in siblings with congenital abnormalities reminiscent of fanconi anemia.
Hum Genet
; 142(9): 1417-1427, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558815
10.
Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures.
EMBO Rep
; 22(5): e51851, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33932076
11.
XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.
Nature
; 541(7635): 87-91, 2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28002403
12.
The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling.
J Biol Chem
; 297(3): 101041, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34358560
13.
Perspectives on PARPs in S Phase.
Trends Genet
; 35(6): 412-422, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31036342
14.
Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair.
Nucleic Acids Res
; 48(12): 6672-6684, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504494
15.
Characterization of a novel loss-of-function variant in TDP2 in two adult patients with spinocerebellar ataxia autosomal recessive 23 (SCAR23).
J Hum Genet
; 65(12): 1135-1141, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32651480
16.
PARP-3 and APLF function together to accelerate nonhomologous end-joining.
Mol Cell
; 41(1): 33-45, 2011 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21211721
17.
Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.
Nucleic Acids Res
; 45(5): 2546-2557, 2017 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27965414
18.
The Rev1 interacting region (RIR) motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand break repair.
J Biol Chem
; 292(39): 16024-16031, 2017 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28821613
19.
APLF promotes the assembly and activity of non-homologous end joining protein complexes.
EMBO J
; 32(1): 112-25, 2013 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23178593
20.
Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2.
Biochem J
; 473(13): 1869-79, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27099339