Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer.

Dreyer, Stephan B; Upstill-Goddard, Rosie; Paulus-Hock, Viola; Paris, Clara; Lampraki, Eirini-Maria; Dray, Eloise; Serrels, Bryan; Caligiuri, Giuseppina; Rebus, Selma; Plenker, Dennis; Galluzzo, Zachary; Brunton, Holly; Cunningham, Richard; Tesson, Mathias; Nourse, Craig; Bailey, Ulla-Maja; Jones, Marc; Moran-Jones, Kim; Wright, Derek W; Duthie, Fraser; Oien, Karin; Evers, Lisa; McKay, Colin J; McGregor, Grant A; Gulati, Aditi; Brough, Rachel; Bajrami, Ilirjana; Pettitt, Stephan; Dziubinski, Michele L; Candido, Juliana; Balkwill, Frances; Barry, Simon T; Grützmann, Robert; Rahib, Lola; Johns, Amber; Pajic, Marina; Froeling, Fieke E M; Beer, Phillip; Musgrove, Elizabeth A; Petersen, Gloria M; Ashworth, Alan; Frame, Margaret C; Crawford, Howard C; Simeone, Diane M; Lord, Chris; Mukhopadhyay, Debabrata; Pilarsky, Christian; Tuveson, David A; Cooke, Susanna L; Jamieson, Nigel B.

Gastroenterology ; 160(1): 362-377.e13, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33039466

2.

Cancer-related inflammation.

Candido, Juliana; Hagemann, Thorsten.

J Clin Immunol ; 33 Suppl 1: S79-84, 2013 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-23225204

3.

CD73 controls Myosin II-driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells.

Samain, Remi; Maiques, Oscar; Monger, Joanne; Lam, Hoyin; Candido, Juliana; George, Samantha; Ferrari, Nicola; KohIhammer, Leonie; Lunetto, Sophia; Varela, Adrian; Orgaz, Jose L; Vilardell, Felip; Olsina, Jorge Juan; Matias-Guiu, Xavier; Sarker, Debashis; Biddle, Adrian; Balkwill, Frances R; Eyles, Jim; Wilkinson, Robert W; Kocher, Hemant M; Calvo, Fernando; Wells, Claire M; Sanz-Moreno, Victoria.

Sci Adv ; 9(42): eadi0244, 2023 10 20.

Artigo em Inglês | MEDLINE | ID: mdl-37851808

4.

Kallikrein-Related Peptidase 6 Is Associated with the Tumour Microenvironment of Pancreatic Ductal Adenocarcinoma.

Candido, Juliana B; Maiques, Oscar; Boxberg, Melanie; Kast, Verena; Peerani, Eleonora; Tomás-Bort, Elena; Weichert, Wilko; Sananes, Amiram; Papo, Niv; Magdolen, Viktor; Sanz-Moreno, Victoria; Loessner, Daniela.

Cancers (Basel) ; 13(16)2021 Aug 05.

Artigo em Inglês | MEDLINE | ID: mdl-34439122

5.

3D approaches to model the tumor microenvironment of pancreatic cancer.

Tomás-Bort, Elena; Kieler, Markus; Sharma, Shreya; Candido, Juliana B; Loessner, Daniela.

Theranostics ; 10(11): 5074-5089, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32308769

6.

Cancer associated fibroblast FAK regulates malignant cell metabolism.

Demircioglu, Fevzi; Wang, Jun; Candido, Juliana; Costa, Ana S H; Casado, Pedro; de Luxan Delgado, Beatriz; Reynolds, Louise E; Gomez-Escudero, Jesus; Newport, Emma; Rajeeve, Vinothini; Baker, Ann-Marie; Roy-Luzarraga, Marina; Graham, Trevor A; Foster, Julie; Wang, Yu; Campbell, James J; Singh, Rajinder; Zhang, Penglie; Schall, Thomas J; Balkwill, Frances R; Sosabowski, Jane; Cutillas, Pedro R; Frezza, Christian; Sancho, Patricia; Hodivala-Dilke, Kairbaan.

Nat Commun ; 11(1): 1290, 2020 03 10.

Artigo em Inglês | MEDLINE | ID: mdl-32157087

7.

Cell Recovery of Hydrogel-Encapsulated Cells for Molecular Analysis.

Peerani, Eleonora; Candido, Juliana B; Loessner, Daniela.

Methods Mol Biol ; 2054: 3-21, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31482445

8.

Discrepancies in the Tumor Microenvironment of Spontaneous and Orthotopic Murine Models of Pancreatic Cancer Uncover a New Immunostimulatory Phenotype for B Cells.

Spear, Sarah; Candido, Juliana B; McDermott, Jacqueline R; Ghirelli, Cristina; Maniati, Eleni; Beers, Stephen A; Balkwill, Frances R; Kocher, Hemant M; Capasso, Melania.

Front Immunol ; 10: 542, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-30972056

9.

CSF1R⁺ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype.

Candido, Juliana B; Morton, Jennifer P; Bailey, Peter; Campbell, Andrew D; Karim, Saadia A; Jamieson, Thomas; Lapienyte, Laura; Gopinathan, Aarthi; Clark, William; McGhee, Ewan J; Wang, Jun; Escorcio-Correia, Monica; Zollinger, Raphael; Roshani, Rozita; Drew, Lisa; Rishi, Loveena; Arkell, Rebecca; Evans, T R Jeffry; Nixon, Colin; Jodrell, Duncan I; Wilkinson, Robert W; Biankin, Andrew V; Barry, Simon T; Balkwill, Frances R; Sansom, Owen J.

Cell Rep ; 23(5): 1448-1460, 2018 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-29719257

10.

CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma.

Steele, Colin W; Karim, Saadia A; Leach, Joshua D G; Bailey, Peter; Upstill-Goddard, Rosanna; Rishi, Loveena; Foth, Mona; Bryson, Sheila; McDaid, Karen; Wilson, Zena; Eberlein, Catherine; Candido, Juliana B; Clarke, Mairi; Nixon, Colin; Connelly, John; Jamieson, Nigel; Carter, C Ross; Balkwill, Frances; Chang, David K; Evans, T R Jeffry; Strathdee, Douglas; Biankin, Andrew V; Nibbs, Robert J B; Barry, Simon T; Sansom, Owen J; Morton, Jennifer P.

Cancer Cell ; 29(6): 832-845, 2016 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-27265504

11.

Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits PparÎ³ expression and promotes pancreatic cancer progression in mice.

Maniati, Eleni; Bossard, Maud; Cook, Natalie; Candido, Juliana B; Emami-Shahri, Nia; Nedospasov, Sergei A; Balkwill, Frances R; Tuveson, David A; Hagemann, Thorsten.

J Clin Invest ; 121(12): 4685-99, 2011 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-22056382

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