Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

The microRNA miR-31 inhibits CD8⁺ T cell function in chronic viral infection.

Moffett, Howell F; Cartwright, Adam N R; Kim, Hye-Jung; Godec, Jernej; Pyrdol, Jason; Äijö, Tarmo; Martinez, Gustavo J; Rao, Anjana; Lu, Jun; Golub, Todd R; Cantor, Harvey; Sharpe, Arlene H; Novina, Carl D; Wucherpfennig, Kai W.

Nat Immunol ; 18(7): 791-799, 2017 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-28530712

2.

A p85α-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells.

Leavenworth, Jianmei W; Verbinnen, Bert; Yin, Jie; Huang, Huicong; Cantor, Harvey.

Nat Immunol ; 16(1): 96-106, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25436971

3.

Mechanism of EBV inducing anti-tumour immunity and its therapeutic use.

Choi, Il-Kyu; Wang, Zhe; Ke, Qiang; Hong, Min; Paul, Dereck W; Fernandes, Stacey M; Hu, Zhuting; Stevens, Jonathan; Guleria, Indira; Kim, Hye-Jung; Cantor, Harvey; Wucherpfennig, Kai W; Brown, Jennifer R; Ritz, Jerome; Zhang, Baochun.

Nature ; 590(7844): 157-162, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33361812

4.

Definition of the contribution of an Osteopontin-producing CD11c⁺ microglial subset to Alzheimer's disease.

Qiu, Yiguo; Shen, Xianli; Ravid, Orly; Atrakchi, Dana; Rand, Daniel; Wight, Andrew E; Kim, Hye-Jung; Liraz-Zaltsman, Sigal; Cooper, Itzik; Schnaider Beeri, Michal; Cantor, Harvey.

Proc Natl Acad Sci U S A ; 120(6): e2218915120, 2023 02 07.

Artigo em Inglês | MEDLINE | ID: mdl-36730200

5.

Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain.

Shen, Xianli; Qiu, Yiguo; Wight, Andrew E; Kim, Hye-Jung; Cantor, Harvey.

Proc Natl Acad Sci U S A ; 119(8)2022 02 22.

Artigo em Inglês | MEDLINE | ID: mdl-35177477

6.

Antibody-mediated blockade of the IL23 receptor destabilizes intratumoral regulatory T cells and enhances immunotherapy.

Wight, Andrew E; Sido, Jessica M; Degryse, Sandrine; Ao, Lin; Nakagawa, Hidetoshi; Qiu Vivian, Yiguo; Shen, Xianli; Oseghali, Oba; Kim, Hye-Jung; Cantor, Harvey.

Proc Natl Acad Sci U S A ; 119(18): e2200757119, 2022 05 03.

Artigo em Inglês | MEDLINE | ID: mdl-35482921

7.

Erratum: The microRNA miR-31 inhibits CD8⁺ T cell function in chronic viral infection.

Moffett, Howell F; Cartwright, Adam N R; Kim, Hye-Jung; Godec, Jernej; Pyrdol, Jason; Äijö, Tarmo; Martinez, Gustavo J; Rao, Anjana; Lu, Jun; Golub, Todd R; Cantor, Harvey; Sharpe, Arlene H; Novina, Carl D; Wucherpfennig, Kai W.

Nat Immunol ; 18(10): 1173, 2017 09 19.

Artigo em Inglês | MEDLINE | ID: mdl-28926530

8.

Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults.

Lopes, Katia de Paiva; Yu, Lei; Shen, Xianli; Qiu, Yiguo; Tasaki, Shinya; Iatrou, Artemis; Beeri, Michal Schnaider; Seyfried, Nicholas T; Menon, Vilas; Wang, Yanling; Schneider, Julie A; Cantor, Harvey; Bennett, David A.

Alzheimers Dement ; 20(1): 525-537, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-37727065

9.

Overcoming Immune Checkpoint Blockade Resistance via EZH2 Inhibition.

Kim, Hye-Jung; Cantor, Harvey; Cosmopoulos, Kat.

Trends Immunol ; 41(10): 948-963, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32976740

10.

Regulatory CD8 T cells that recognize Qa-1 expressed by CD4 T-helper cells inhibit rejection of heart allografts.

Choi, John Y; Eskandari, Siawosh K; Cai, Songjie; Sulkaj, Ina; Assaker, Jean Pierre; Allos, Hazim; AlHaddad, Juliano; Muhsin, Saif A; Alhussain, Eman; Mansouri, Amr; Yeung, Melissa Y; Seelen, Marc A J; Kim, Hye-Jung; Cantor, Harvey; Azzi, Jamil R.

Proc Natl Acad Sci U S A ; 117(11): 6042-6046, 2020 03 17.

Artigo em Inglês | MEDLINE | ID: mdl-32111690

11.

Renegade T cell clones and autoimmune disease.

Cantor, Harvey.

Proc Natl Acad Sci U S A ; 120(31): e2310236120, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37467287

12.

Comparative transcriptome analysis reveals distinct genetic modules associated with Helios expression in intratumoral regulatory T cells.

Yates, Kathleen; Bi, Kevin; Haining, W Nicholas; Cantor, Harvey; Kim, Hye-Jung.

Proc Natl Acad Sci U S A ; 115(9): 2162-2167, 2018 02 27.

Artigo em Inglês | MEDLINE | ID: mdl-29440380

13.

Chromatin remodeling by the NuRD complex regulates development of follicular helper and regulatory T cells.

Shen, Erxia; Wang, Qin; Rabe, Hardis; Liu, Wenquan; Cantor, Harvey; Leavenworth, Jianmei W.

Proc Natl Acad Sci U S A ; 115(26): 6780-6785, 2018 06 26.

Artigo em Inglês | MEDLINE | ID: mdl-29891681

14.

Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4⁺ and CD8⁺ T cell responses.

Choi, Il-Kyu; Wang, Zhe; Ke, Qiang; Hong, Min; Qian, Yu; Zhao, Xiujuan; Liu, Yuting; Kim, Hye-Jung; Ritz, Jerome; Cantor, Harvey; Rajewsky, Klaus; Wucherpfennig, Kai W; Zhang, Baochun.

Proc Natl Acad Sci U S A ; 115(4): E686-E695, 2018 01 23.

Artigo em Inglês | MEDLINE | ID: mdl-29311309

15.

Regulatory T cells subdue an autoimmune disease.

Kim, Hye-Jung; Cantor, Harvey.

Nature ; 572(7770): 443-445, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-31427795

16.

In vivo discovery of immunotherapy targets in the tumour microenvironment.

Zhou, Penghui; Shaffer, Donald R; Alvarez Arias, Diana A; Nakazaki, Yukoh; Pos, Wouter; Torres, Alexis J; Cremasco, Viviana; Dougan, Stephanie K; Cowley, Glenn S; Elpek, Kutlu; Brogdon, Jennifer; Lamb, John; Turley, Shannon J; Ploegh, Hidde L; Root, David E; Love, J Christopher; Dranoff, Glenn; Hacohen, Nir; Cantor, Harvey; Wucherpfennig, Kai W.

Nature ; 506(7486): 52-7, 2014 Feb 06.

Artigo em Inglês | MEDLINE | ID: mdl-24476824

17.

MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8+ T cells and contributes to protection against infection.

Bian, Yao; Shang, Shaobin; Siddiqui, Sarah; Zhao, Jie; Joosten, Simone A; Ottenhoff, Tom H M; Cantor, Harvey; Wang, Chyung-Ru.

PLoS Pathog ; 13(5): e1006384, 2017 May.

Artigo em Inglês | MEDLINE | ID: mdl-28475642

18.

Î³Î´ T Cells Contribute to Injury in the Developing Brain.

Albertsson, Anna-Maj; Zhang, Xiaoli; Vontell, Regina; Bi, Dan; Bronson, Roderick T; Supramaniam, Veena; Baburamani, Ana A; Hua, Sha; Nazmi, Arshed; Cardell, Susanna; Zhu, Changlian; Cantor, Harvey; Mallard, Carina; Hagberg, Henrik; Leavenworth, Jianmei W; Wang, Xiaoyang.

Am J Pathol ; 188(3): 757-767, 2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-29248460

19.

Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity.

Nakagawa, Hidetoshi; Sido, Jessica M; Reyes, Edwin E; Kiers, Valerie; Cantor, Harvey; Kim, Hye-Jung.

Proc Natl Acad Sci U S A ; 113(22): 6248-53, 2016 May 31.

Artigo em Inglês | MEDLINE | ID: mdl-27185917

20.

Intracellular osteopontin regulates homeostasis and function of natural killer cells.

Leavenworth, Jianmei W; Verbinnen, Bert; Wang, Qin; Shen, Erxia; Cantor, Harvey.

Proc Natl Acad Sci U S A ; 112(2): 494-9, 2015 Jan 13.

Artigo em Inglês | MEDLINE | ID: mdl-25550515

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