Detalhe da pesquisa
1.
In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.
Nature
; 589(7843): 608-614, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33408413
2.
Mesenchymal Stem Cell-Derived Extracellular Vesicles Alleviate M1 Microglial Activation in Brain Injury of Mice With Subarachnoid Hemorrhage via microRNA-140-5p Delivery.
Int J Neuropsychopharmacol
; 25(4): 328-338, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35015859
3.
Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts.
Proc Natl Acad Sci U S A
; 116(38): 18983-18993, 2019 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31481614
4.
Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome.
Int J Mol Sci
; 23(10)2022 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35628310
5.
Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1.
Proc Natl Acad Sci U S A
; 111(22): E2261-70, 2014 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24843141
6.
Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome.
Genome Res
; 23(2): 260-9, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23152449
7.
MiR-136 targets E2F1 to reverse cisplatin chemosensitivity in glioma cells.
J Neurooncol
; 120(1): 43-53, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25139024
8.
From cellular characteristics to disease diagnosis: uncovering phenotypes with supercells.
PLoS Comput Biol
; 9(9): e1003215, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24039568
9.
Development of an accelerated cellular model for early changes in Alzheimer's disease.
Sci Rep
; 13(1): 18384, 2023 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37884611
10.
Research on the development and testing methods of physical education and agility training equipment in universities.
Front Psychol
; 14: 1155490, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37457097
11.
Lonafarnib and everolimus reduce pathology in iPSC-derived tissue engineered blood vessel model of Hutchinson-Gilford Progeria Syndrome.
Sci Rep
; 13(1): 5032, 2023 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36977745
12.
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly.
Nat Cell Biol
; 5(3): 242-8, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12577065
13.
Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging.
Arterioscler Thromb Vasc Biol
; 30(11): 2301-9, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20798379
14.
A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model.
Proc Natl Acad Sci U S A
; 105(41): 15902-7, 2008 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18838683
15.
The Potentials of Methylene Blue as an Anti-Aging Drug.
Cells
; 10(12)2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34943887
16.
Effect of astaxanthin on neuron damage, inflammatory factors expressions and oxidative stress in mice with subarachnoid hemorrhage.
Am J Transl Res
; 13(11): 13043-13050, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34956522
17.
Ultraviolet radiation protection potentials of Methylene Blue for human skin and coral reef health.
Sci Rep
; 11(1): 10871, 2021 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050204
18.
Mechanisms of angiogenic incompetence in Hutchinson-Gilford progeria via downregulation of endothelial NOS.
Aging Cell
; 20(7): e13388, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34086398
19.
Gene targeting techniques for Huntington's disease.
Ageing Res Rev
; 70: 101385, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34098113
20.
A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome.
Nat Med
; 27(3): 536-545, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33707773