RESUMO
Chronic urticaria (CU) is defined as the occurrence of spontaneous wheals for a duration of more than 6 weeks and is the most frequent skin disease, with prevalence ranging between 15 and 25%, and is a seriously disabling condition, with social isolation and mood changes causing a significant degree of dysfunction and quality of life impairment to many patients. The main clinical features of CU are the repeated occurrence of transient eruptions of pruritic wheals or patchy erythema on the skin that last less than 24 hours and disappear without sequelae. CU is often defined as chronic idiopathic urticaria (CIU) because the causes of CU remain unknown in the great majority (70-95%) of patients. Drugs, food, viruses, alimentary conservative substances or inhalant substances often seem to be involved in determining CIU skin flare. Despite a general agreement that bacteria infections and parasitic infestations can be involved in the pathogenesis of CIU, proven evidence of these relationships is lacking. The aim of the present study is to evaluate the prevalence of Helicobacter pylori (Hp) infection, and the extension and severity of gastritis in a group of CIU patients compared to controls and to evaluate the effectiveness of eradication of Hp on the CIU symptomatology, and the role of Hp infection in pathogenesis of CIU.
Assuntos
Antibacterianos/uso terapêutico , Gastrite/tratamento farmacológico , Infecções por Helicobacter/tratamento farmacológico , Helicobacter pylori/isolamento & purificação , Urticária/tratamento farmacológico , Adolescente , Adulto , Idoso , Biópsia , Testes Respiratórios , Estudos de Casos e Controles , Feminino , Gastrite/diagnóstico , Gastrite/epidemiologia , Gastrite/microbiologia , Gastroscopia , Infecções por Helicobacter/diagnóstico , Infecções por Helicobacter/epidemiologia , Infecções por Helicobacter/microbiologia , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Indução de Remissão , Cidade de Roma , Índice de Gravidade de Doença , Fatores de Tempo , Resultado do Tratamento , Urticária/diagnóstico , Urticária/epidemiologia , Urticária/microbiologia , Adulto JovemRESUMO
Nickel deficiency leads to reduced iron content in organs and to reduced hemoglobin levels and haematocrit counts. We carried out a clinical trial of oral hyposensitization therapy with low doses of nickel on a group of 20 patients affected by systemic allergy to this sensitizer element and with a chronic relapsing low hemoglobin level and haematocrit count. We obtained interesting results on maintaining these values in treated patients.
Assuntos
Dessensibilização Imunológica , Hematócrito , Hemoglobinas/metabolismo , Hipersensibilidade/terapia , Níquel/administração & dosagem , Níquel/imunologia , Administração Oral , Biomarcadores/sangue , Dessensibilização Imunológica/efeitos adversos , Humanos , Hipersensibilidade/sangue , Hipersensibilidade/diagnóstico , Hipersensibilidade/imunologia , Maryland , Níquel/efeitos adversos , Testes do Emplastro , Fatores de Tempo , Resultado do TratamentoRESUMO
In Western countries the phenomenon of "tattooing" is expanding and tattoos are considered a new fashion among young people. In this paper we briefly trace the history of tattooing, the techniques used, the analysis of pigments used, and their possible adverse reactions. We also carried out a review of the international literature on the use of Q-switched laser in tattoo removal and its complications, and we describe our experience in the use of this technique.
Assuntos
Tinta , Terapia a Laser/instrumentação , Lasers de Estado Sólido , Tatuagem , História do Século XX , História do Século XXI , Humanos , Terapia a Laser/efeitos adversos , Terapia a Laser/história , Lasers de Estado Sólido/efeitos adversos , Lasers de Estado Sólido/história , Masculino , Tatuagem/história , Fatores de Tempo , Resultado do TratamentoRESUMO
Anetoderma is a benign condition characterized by round or oval macular lesions with focal loss of dermal elastic tissue resulting in localized areas of flaccid or herniated saclike skin. Often, the anetoderma is associated with immuno-mediated pathogenetic mechanism. In this article, we describe the association between anetoderma and autoimmune diseases, by underlining the role and the action of macrophages as a possible etiopathogenesis.