Detalhe da pesquisa
1.
Design and synthesis of novel proline based factor XIa selective inhibitors as leads for potential new anticoagulants.
Bioorg Med Chem Lett
; 30(16): 127072, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32340773
2.
Imidazopyridyl compounds as aldosterone synthase inhibitors.
Bioorg Med Chem Lett
; 27(2): 143-146, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27979595
3.
N-Substituted tertiary and O-substituted quaternary carbon stereogenic centers by site-, diastereo- and enantioselective vinylogous Mannich reactions.
Tetrahedron Lett
; 56(23): 3489-3493, 2015 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28775388
4.
Si-free enolate Claisen rearrangements of enamido substrates.
Org Biomol Chem
; 10(7): 1406-10, 2012 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22215234
5.
High-resolution crystal structures of factor XIa coagulation factor in complex with nonbasic high-affinity synthetic inhibitors.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 68(Pt 4): 404-8, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22505407
6.
Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead MSC-4106.
J Med Chem
; 65(13): 9206-9229, 2022 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35763499
7.
Practical and highly enantioselective synthesis of beta-alkynyl-beta-amino esters through Ag-catalyzed asymmetric mannich reactions of silylketene acetals and alkynyl imines.
Org Lett
; 7(13): 2711-3, 2005 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15957928
8.
Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys.
ACS Med Chem Lett
; 6(5): 573-8, 2015 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26005536
9.
A highly efficient and practical method for catalytic asymmetric vinylogous Mannich (AVM) reactions.
Angew Chem Int Ed Engl
; 45(43): 7230-3, 2006 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-17042037
10.
A practical protocol for the highly E-selective formation of aryl-substituted silylketene acetals.
Org Lett
; 12(16): 3712-5, 2010 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20669957