Detalhe da pesquisa
1.
Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM.
Immunity
; 50(6): 1412-1424.e6, 2019 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31076360
2.
Heterocyclic Iminoquinones and Quinones from the National Cancer Institute (NCI, USA) COMPARE Analysis.
Molecules
; 28(13)2023 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446864
3.
CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages.
J Biol Chem
; 297(6): 101417, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34793837
4.
SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration.
Int J Mol Sci
; 23(3)2022 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163535
5.
Poxviral protein E3-altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor-stimulated immune responses.
J Biol Chem
; 293(39): 14989-15001, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30111593
6.
N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines.
Bioorg Chem
; 84: 418-433, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30554081
7.
Anti-Cancer Activity of Phenyl and Pyrid-2-yl 1,3-Substituted Benzo[1,2,4]triazin-7-ones and Stable Free Radical Precursors.
Molecules
; 23(3)2018 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29510488
8.
Innate antiviral signalling in the central nervous system.
Trends Immunol
; 35(2): 79-87, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24316012
9.
Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition.
Bioorg Med Chem
; 24(16): 3565-70, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27290691
10.
SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter.
J Immunol
; 192(10): 4821-32, 2014 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24711619
11.
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon.
Nat Commun
; 14(1): 3513, 2023 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37316487
12.
COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substrates.
Bioorg Med Chem
; 20(10): 3223-32, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22522008
13.
SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration.
Front Neurosci
; 16: 852114, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35431772
14.
Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity.
Cell Rep
; 40(6): 111167, 2022 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35947948
15.
Effects of titanocene dichloride derivatives on prostate cancer cells, specifically DNA damage-induced apoptosis.
Prostate
; 71(2): 111-24, 2011 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20665530
16.
First synthesis of an aziridinyl fused pyrrolo[1,2-a]benzimidazole and toxicity evaluation towards normal and breast cancer cell lines.
Org Biomol Chem
; 9(19): 6700-6, 2011 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21808774
17.
Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis.
Nucleic Acids Res
; 37(18): 6028-41, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19671522
18.
DNA polymerase eta, a key protein in translesion synthesis in human cells.
Subcell Biochem
; 50: 189-209, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20012583
19.
DNA Damage Tolerance Pathways in Human Cells: A Potential Therapeutic Target.
Front Oncol
; 11: 822500, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35198436
20.
Detection of Viral Infections by Innate Immunity.
Biochem Pharmacol
; 183: 114316, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33152343