Detalhe da pesquisa
1.
Colocalization analysis of 3' UTR alternative polyadenylation quantitative trait loci reveals novel mechanisms underlying associations with lung function.
Hum Mol Genet
; 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38569558
2.
Blood-based Transcriptomic and Proteomic Biomarkers of Emphysema.
Am J Respir Crit Care Med
; 209(3): 273-287, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37917913
3.
Bridging the splicing gap in human genetics with long-read RNA sequencing: finding the protein isoform drivers of disease.
Hum Mol Genet
; 31(R1): R123-R136, 2022 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35960994
4.
Activation of CD8+ T Cells in Chronic Obstructive Pulmonary Disease Lung.
Am J Respir Crit Care Med
; 208(11): 1177-1195, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37756440
5.
Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function.
Am J Respir Crit Care Med
; 208(11): 1196-1205, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37788444
6.
Integrating Genetics, Transcriptomics, and Proteomics in Lung Tissue to Investigate Chronic Obstructive Pulmonary Disease.
Am J Respir Cell Mol Biol
; 68(6): 651-663, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36780661
7.
Heterogeneity and Progression of Chronic Obstructive Pulmonary Disease: Emphysema-Predominant and Non-Emphysema-Predominant Disease.
Am J Epidemiol
; 192(10): 1647-1658, 2023 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37160347
8.
From pre-COPD to COPD: a Simple, Low cost and easy to IMplement (SLIM) risk calculator.
Eur Respir J
; 62(3)2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37678951
9.
Development of a Blood-based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease.
Am J Respir Crit Care Med
; 205(2): 161-170, 2022 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34739356
10.
Alpha-1 Antitrypsin MZ Heterozygosity Is an Endotype of Chronic Obstructive Pulmonary Disease.
Am J Respir Crit Care Med
; 205(3): 313-323, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34762809
11.
Blood RNA sequencing shows overlapping gene expression across COPD phenotype domains.
Thorax
; 77(2): 115-122, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34168019
12.
Blood gene expression risk profiles and interstitial lung abnormalities: COPDGene and ECLIPSE cohort studies.
Respir Res
; 23(1): 157, 2022 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35715807
13.
Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.
Respir Res
; 23(1): 97, 2022 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35449067
14.
Improved prediction of smoking status via isoform-aware RNA-seq deep learning models.
PLoS Comput Biol
; 17(10): e1009433, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34634029
15.
Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene.
PLoS Genet
; 15(7): e1008229, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31269066
16.
Cigarette smoking-associated isoform switching and 3' UTR lengthening via alternative polyadenylation.
Genomics
; 113(6): 4184-4195, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34763026
17.
Statistical considerations for the analysis of massively parallel reporter assays data.
Genet Epidemiol
; 44(7): 785-794, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32681690
18.
Lung proteomic biomarkers associated with chronic obstructive pulmonary disease.
Am J Physiol Lung Cell Mol Physiol
; 321(6): L1119-L1130, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34668408
19.
Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD.
Respir Res
; 22(1): 127, 2021 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33906653
20.
Genome-Wide Association Study: Functional Variant rs2076295 Regulates Desmoplakin Expression in Airway Epithelial Cells.
Am J Respir Crit Care Med
; 202(9): 1225-1236, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32551799