Detalhe da pesquisa
1.
Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress.
J Biol Chem
; 298(10): 102494, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36115461
2.
Dissecting Alzheimer's disease pathogenesis in human 2D and 3D models.
Mol Cell Neurosci
; 110: 103568, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33068718
3.
Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53.
J Neurosci Res
; 93(11): 1728-39, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26251011
4.
Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain.
Biochim Biophys Acta
; 1832(8): 1249-59, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23603808
5.
Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome.
Biochim Biophys Acta
; 1822(2): 130-8, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22009041
6.
Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment.
Biochim Biophys Acta
; 1812(4): 480-7, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21241799
7.
Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain.
Int J Neuropsychopharmacol
; 15(7): 981-7, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21767440
8.
Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action.
Pharmacol Res
; 63(3): 172-80, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21193043
9.
Generation of reactive oxygen species by beta amyloid fibrils and oligomers involves different intra/extracellular pathways.
Amino Acids
; 38(4): 1101-6, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19582548
10.
Wild type but not mutant APP is involved in protective adaptive responses against oxidants.
Amino Acids
; 39(1): 271-83, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20063202
11.
Glutathionylation of the pro-apoptotic protein p53 in Alzheimer's disease brain: implications for AD pathogenesis.
Neurochem Res
; 34(4): 727-33, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19199029
12.
Mitochondria as Potential Targets in Alzheimer Disease Therapy: An Update.
Front Pharmacol
; 10: 902, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31507410
13.
Oxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View.
Oxid Med Cell Longev
; 2019: 2105607, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31210837
14.
γ-Oryzanol Improves Cognitive Function and Modulates Hippocampal Proteome in Mice.
Nutrients
; 11(4)2019 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30935111
15.
Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease.
Neurobiol Dis
; 29(3): 456-64, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18077176
16.
Effects of oxidative and nitrosative stress in brain on p53 proapoptotic protein in amnestic mild cognitive impairment and Alzheimer disease.
Free Radic Biol Med
; 45(1): 81-5, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18439434
17.
IMiQ: a novel protein quality control compartment protecting mitochondrial functional integrity.
Mol Biol Cell
; 29(3): 256-269, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29212875
18.
Role of Mitochondrial Protein Quality Control in Oxidative Stress-induced Neurodegenerative Diseases.
Curr Alzheimer Res
; 13(2): 164-73, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26391041
19.
Amyloid ß-peptides interfere with mitochondrial preprotein import competence by a coaggregation process.
Mol Biol Cell
; 27(21): 3257-3272, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27630262
20.
Oxidative Stress and Mitochondrial Damage in Neurodegenerative Diseases: From Molecular Mechanisms to Targeted Therapies.
Oxid Med Cell Longev
; 2020: 1270256, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32454930