Detalhe da pesquisa
1.
Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore.
Genes Dev
; 34(23-24): 1619-1636, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33122293
2.
TRF2-independent chromosome end protection during pluripotency.
Nature
; 589(7840): 103-109, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33239783
3.
Telomere Loop Dynamics in Chromosome End Protection.
Mol Cell
; 71(4): 510-525.e6, 2018 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30033372
4.
CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle.
Nature
; 575(7783): 523-527, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31723267
5.
Phasor histone FLIM-FRET microscopy quantifies spatiotemporal rearrangement of chromatin architecture during the DNA damage response.
Proc Natl Acad Sci U S A
; 116(15): 7323-7332, 2019 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30918123
6.
Synthetic lethality of cytolytic HSV-1 in cancer cells with ATRX and PML deficiency.
J Cell Sci
; 132(5)2019 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30745338
7.
Cell death during crisis is mediated by mitotic telomere deprotection.
Nature
; 522(7557): 492-6, 2015 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26108857
8.
The telomere deprotection response is functionally distinct from the genomic DNA damage response.
Mol Cell
; 51(2): 141-55, 2013 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23850488
9.
Alternative lengthening of telomeres: models, mechanisms and implications.
Nat Rev Genet
; 11(5): 319-30, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20351727
10.
Mitosis, double strand break repair, and telomeres: a view from the end: how telomeres and the DNA damage response cooperate during mitosis to maintain genome stability.
Bioessays
; 36(11): 1054-61, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25171524
11.
Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres.
iScience
; 27(1): 108655, 2024 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38213617
12.
ZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway.
Nat Commun
; 15(1): 2210, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38472229
13.
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.
Nat Commun
; 15(1): 1385, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38360978
14.
Control of telomere length by a trimming mechanism that involves generation of t-circles.
EMBO J
; 28(7): 799-809, 2009 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19214183
15.
Five dysfunctional telomeres predict onset of senescence in human cells.
EMBO Rep
; 13(1): 52-9, 2011 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22157895
16.
Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells.
Cell Chem Biol
; 30(12): 1652-1665.e6, 2023 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38065101
17.
Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination.
Nucleic Acids Res
; 38(1): 182-9, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19858100
18.
Chromatin mobility and relocation in DNA repair.
Trends Cell Biol
; 31(10): 843-855, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34183232
19.
BRG1 knockdown inhibits proliferation through multiple cellular pathways in prostate cancer.
Clin Epigenetics
; 13(1): 37, 2021 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596994
20.
Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.
Clin Cancer Res
; 27(15): 4338-4352, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33994371