A novel series colorimetric and off-on fluorescent chemosensors for Fe3+ based on rhodamine B derivative.

A novel series colorimetric and off-on fluorescent chemosensors (2a, 2b, 2c) were designed and synthesized, which showed reversible and highly selective and sensitive recognition toward Fe(3+) over other examined metal ions. Upon addition of Fe(3+), sensors (2a, 2b) exhibit remarkably and 2c exhibits moderate enhanced absorbance intensity and color change from colorless to pink in CH(3)OH-H(2)O(1:1, v/v). The three compounds (2a, 2b, 2c) may therefore be applicable as rhodamine-based turn-on type fluorescent chemosensors.

Three colorimetric and off-on fluorescent chemosensors for Fe3+ in aqueous media.

Three Rhodamine B derivatives were synthesized and characterized by ESI-MS, NMR, HR-MS and IR. The probes exhibit high selectivity and sensitivity towards Fe(3+) over other metal ions in CH3CN-water. Upon the addition of Fe(3+), the spirocyclic ring of the probe was opened and a significant enhancement of visible color and fluorescence within the range of 540-700 nm was observed. The colorimetric and fluorescent response to Fe(3+) can be conveniently detected even by the naked eye, which provides a facile method for the visual detection of Fe(3+). Job's plot, fluorescence titration and MS indicated the formation of 1:2 complexes between the probes and Fe(3+). The reversibility of the reaction establishes the potential of these probes as chemosensors for Fe(3+) detection.

Effects of exercise-based home pulmonary rehabilitation on patients with chronic obstructive pulmonary disease: An overview of systematic review.

BACKGROUND: Clinical research on exercise-based home pulmonary rehabilitation (HPR) effectiveness in chronic obstructive pulmonary disease (COPD) treatment is rising, as are associated systematic reviews/meta-analyses (SRs/MAs). However, different SRs/MAs vary in outcome indicators, analysis methodologies, literature quality, and findings. This overview aimed to describe the findings of these SRs/MAs and assess their methodological quality. METHODS: From inception until April 2022, we searched PubMed, Web of Science, Cochrane Library, EMBASE, China National Knowledge Infrastructure (CNKI), and Wan Fang. Two researchers searched these SRs/MAs separately, collected the data, and cross-checked it using predetermined rules. The Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR 2) was used to evaluate the methodological quality of each contained SR/MA. The evidence was assessed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2009 (PRISMA-2009). The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) was used to determine the validity of the results. RESULTS: A total of 433 records were found, with 44 chosen for full-text review. There were 11 SRs/MAs that matched the inclusion criteria. Our overview included studies published from 2010 to 2022. According to the AMSTAR 2 tool, one had low methodological quality, while the other 10 SRs/MAs had very low quality. The PRISMA statement revealed a low rate of complete reporting for eight items. The GRADE tool, on the other hand, revealed that the evidence quality for most outcomes was very low to moderate. CONCLUSION: According to current research, exercise-based HPR may benefit COPD patients. Nevertheless, this finding is restricted by the low quality of the included SRs/MAs. And more high-quality and large-sample studies are needed in the future. PROSPERO: ID: CRD42022322768. https://www.crd.york.ac.uk/prospero/#recordDetails.

1,1-(Biphenyl-2,2'-diyldi-oxy)-3,3,5,5-tetra-kis-(4-bromo-methyl-phen-oxy)cyclo-triphosphazene.

In the title compound, C(40)H(32)Br(4)N(3)O(6)P(3), the cyclo-triphos-phazene ring adopts a planar conformation, with an r.m.s. deviation of 0.0247 Å. In the crystal, there is a weak inter-molecular C-H⋯O hydrogen bond as well as short inter-molecular Br⋯Br contacts [3.3352 (12) Å].