Detalhe da pesquisa
1.
Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity.
Nat Chem Biol
; 17(11): 1157-1167, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34675414
2.
Structural basis of PROTAC cooperative recognition for selective protein degradation.
Nat Chem Biol
; 13(5): 514-521, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28288108
3.
3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation.
J Am Chem Soc
; 140(29): 9299-9313, 2018 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29949369
4.
Correction to "3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation".
J Am Chem Soc
; 141(18): 7644, 2019 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31017404
5.
Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, ß-catenin, and FoxP3.
Cell Chem Biol
; 30(10): 1261-1276.e7, 2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37591251
6.
Structure of an essential GTPase, YsxC, from Thermotoga maritima.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 67(Pt 6): 640-6, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21636901
7.
Development of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins.
J Med Chem
; 64(20): 15477-15502, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34652918
8.
Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System.
Cell Chem Biol
; 27(9): 1151-1163.e6, 2020 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32668202
9.
Understanding and Improving the Membrane Permeability of VH032-Based PROTACs.
ACS Med Chem Lett
; 11(9): 1732-1738, 2020 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32939229
10.
The effect of social fathers on the cognitive skills of out-of-wedlock children in the U.S.
Econ Hum Biol
; 28: 146-159, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29150387
11.
Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds.
J Med Chem
; 61(2): 504-513, 2018 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28595007
12.
Chemical genetics approaches for selective intervention in epigenetics.
Curr Opin Chem Biol
; 33: 186-94, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27423045
13.
Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4.
ACS Chem Biol
; 10(8): 1770-7, 2015 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26035625
14.
Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes.
Science
; 346(6209): 638-641, 2014 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25323695
15.
Interaction between hydrogenase maturation factors HypA and HypB is required for [NiFe]-hydrogenase maturation.
PLoS One
; 7(2): e32592, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22384275
16.
Structural basis for GTP-dependent dimerization of hydrogenase maturation factor HypB.
PLoS One
; 7(1): e30547, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22276211