Detalhe da pesquisa
1.
A dual-action antibiotic that kills Clostridioides difficile vegetative cells and inhibits spore germination.
Proc Natl Acad Sci U S A
; 120(20): e2304110120, 2023 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37155891
2.
Synthesis of Muramyl-δ-Lactam in Spore Peptidoglycan of Clostridioides difficile.
Chembiochem
; 24(11): e202300282, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37072375
3.
Strategy for Treatment of Infected Diabetic Foot Ulcers.
Acc Chem Res
; 54(5): 1080-1093, 2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596041
4.
Unconventional Antibacterials and Adjuvants.
Acc Chem Res
; 54(4): 917-929, 2021 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512995
5.
Hyperbaric oxygen therapy accelerates wound healing in diabetic mice by decreasing active matrix metalloproteinase-9.
Wound Repair Regen
; 28(2): 194-201, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31736209
6.
Susceptibility of Methicillin-Resistant Staphylococcus aureus to Five Quinazolinone Antibacterials.
Antimicrob Agents Chemother
; 64(1)2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611358
7.
The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus.
Antimicrob Agents Chemother
; 63(5)2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858202
8.
Selective small-molecule inhibitors as chemical tools to define the roles of matrix metalloproteinases in disease.
Biochim Biophys Acta Mol Cell Res
; 1864(11 Pt A): 2001-2014, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28435009
9.
Activities of Oxadiazole Antibacterials against Staphylococcus aureus and Other Gram-Positive Bacteria.
Antimicrob Agents Chemother
; 62(8)2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29866865
10.
Acceleration of diabetic wound healing using a novel protease-anti-protease combination therapy.
Proc Natl Acad Sci U S A
; 112(49): 15226-31, 2015 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26598687
11.
Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of Catalysis.
J Am Chem Soc
; 139(5): 2102-2110, 2017 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28099001
12.
Synergistic, collaterally sensitive ß-lactam combinations suppress resistance in MRSA.
Nat Chem Biol
; 11(11): 855-61, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26368589
13.
In Vitro and In Vivo Synergy of the Oxadiazole Class of Antibacterials with ß-Lactams.
Antimicrob Agents Chemother
; 60(9): 5581-8, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27401567
14.
Restructuring of the extracellular matrix in diabetic wounds and healing: A perspective.
Pharmacol Res
; 107: 243-248, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27033051
15.
The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination.
Pharmacol Res
; 113(Pt A): 515-520, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27687955
16.
Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials.
Bioorg Med Chem Lett
; 26(3): 1011-1015, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26733473
17.
The Natural Product Essramycin and Three of Its Isomers Are Devoid of Antibacterial Activity.
J Nat Prod
; 79(4): 1219-22, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27049333
18.
How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function.
Proc Natl Acad Sci U S A
; 110(42): 16808-13, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24085846
19.
The Tipper-Strominger Hypothesis and Triggering of Allostery in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus (MRSA).
J Am Chem Soc
; 137(20): 6500-5, 2015 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25964995
20.
Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one.
J Am Chem Soc
; 137(5): 1738-41, 2015 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25629446