Detalhe da pesquisa
1.
Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development.
Antimicrob Agents Chemother
; 60(3): 1464-75, 2015 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26711771
2.
N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1-XPF.
Bioorg Med Chem Lett
; 25(19): 4104-8, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26321360
3.
Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF.
Bioorg Med Chem Lett
; 25(19): 4097-103, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26318993
4.
Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1.
Antimicrob Agents Chemother
; 58(10): 6032-43, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25070106
5.
Continuous positive airway pressure (CPAP) during the postoperative period for prevention of postoperative morbidity and mortality following major abdominal surgery.
Cochrane Database Syst Rev
; (8): CD008930, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25081420
6.
Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1).
Bioorg Med Chem Lett
; 23(10): 3064-9, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23570789
7.
Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis.
Bioorg Med Chem Lett
; 22(9): 3349-53, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22469702
8.
Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential.
Eur J Med Chem
; 213: 113167, 2021 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33486199
9.
Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation.
Eur J Med Chem
; 214: 113194, 2021 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33548634
10.
Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists.
Eur J Med Chem
; 226: 113805, 2021 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34536667
11.
Ligand-controlled selectivity in the desymmetrization of meso cyclopenten-1,4-diols via rhodium(I)-catalyzed addition of arylboronic acids.
J Org Chem
; 75(12): 4056-68, 2010 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20469847
12.
Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform.
J Med Chem
; 61(10): 4335-4347, 2018 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29701962
13.
Rhodium-catalyzed asymmetric allylic substitution with boronic acid nucleophiles.
Org Lett
; 8(20): 4569-72, 2006 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16986952
14.
Novel cyclic sugar imines: carbohydrate mimics and easily elaborated scaffolds for aza-sugars.
Org Lett
; 4(1): 103-6, 2002 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-11772101
15.
Optimization of an imidazopyridazine series of inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1).
J Med Chem
; 57(8): 3570-87, 2014 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24689770
16.
Prooxidant activity of oxidized alpha-tocopherol in vegetable oils.
J Food Sci
; 74(7): C536-42, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19895457
17.
Glyco- and peptidomimetics from three-component Joullié-Ugi coupling show selective antiviral activity.
J Am Chem Soc
; 127(2): 506-7, 2005 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-15643858
18.
Highly diastereoselective additions to polyhydroxylated pyrrolidine cyclic imines: ready elaboration of aza-sugar scaffolds to create diverse carbohydrate-processing enzyme probes.
Chemistry
; 9(14): 3397-414, 2003 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12866083