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An erratum is given to correct two typos of Eq. (28) in [Opt. Express30(25), 45862 (2022)10.1364/OE.476856]. The corrections do not impact on the results and conclusions of the original article.
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A continuous time-domain adaptive power model of transmitter optical and control algorithm based on atmospheric turbulence channel reciprocity are explored for mitigating the free-space optical communication (FSOC) receiver optical intensity scintillation and bit error rate (BER) deterioration. First, a transmitter optical adaptive power control (OAPC) system architecture using four wavelength optical signals based on atmospheric turbulence channel reciprocity is proposed, and electronically variable optical attenuator (EVOA) and erbium-doped fiber amplifier (EDFA) are employed as the main OAPC units for power adaptation. Moreover, a reciprocity evaluation model for gamma-gamma (G-G) continuous-time signals is generated using the autoregressive moving average (ARMA) stochastic process, which takes into account the delay time and system noise, and a reciprocity-based OPAC algorithm is proposed. Numerical simulations were also performed to analyze the signal reciprocity characteristics under different turbulence, noise, and sampling time mismatch at both ends, as well as the scintillation index (SI) performance under OAPC system operation. Simultaneously, the time-domain signals of continuous quadrature amplitude modulation -16 (QAM-16) and QAM-32 real states are fused with the gamma-gamma (G-G) reciprocal turbulence continuous signals to analyze the probability density function (PDF) and bit error ratio (BER) performance after OAPC correction. Finally, a 64 Gpbs QAM-16 OPAC communication experiment was successfully executed based on an atmospheric turbulence simulator. It is shown that the OAPC correction is carried out using reciprocity at millisecond sampling delay, the light intensity scintillation of the communication signal can be well suppressed, the signal-to-noise ratio (SNR) is greatly improved, the suppression is more obvious under strong turbulence, the overall BER reduction is greater than 2.8 orders of magnitude with the OAPC system, and this trend becomes more pronounced as the received power increases, even reach 6 orders of magnitude in some places. This work provides real time-domain continuous signal samples for real signal generation of communication signals in real turbulence environments, adaptive coding modulation using reciprocity, channel estimation, and optical wavefront adaptive suppression, which are the basis of advanced adaptive signal processing algorithms.
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For orbital angular momentum (OAM) recognition in atmosphere turbulence, how to design a self-adapted model is a challenging problem. To address this issue, an efficient deep learning framework that uses a derived extreme learning machine (ELM) has been put forward. Different from typical neural network methods, the provided analytical machine learning model can match the different OAM modes automatically. In the model selection phase, a multilayer ELM is adopted to quantify the laser spot characteristics. In the parameter optimization phase, a fast iterative shrinkage-thresholding algorithm makes the model present the analytic expression. After the feature extraction of the received intensity distributions, the proposed method develops a relationship between laser spot and OAM mode, thus building the steady neural network architecture for the new received vortex beam. The whole recognition process avoids the trial and error caused by user intervention, which makes the model suitable for a time-varying atmospheric environment. Numerical simulations are conducted on different experimental datasets. The results demonstrate that the proposed method has a better capacity for OAM recognition.
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Secret-key extraction from atmospheric optical channels can generate common keys used by two communicating parties to encrypt their transmitted confidential information. The correlation time of turbulence-induced optical fluctuations imposes a restriction on the number of extracted uncorrelated key bits per second. To break this restriction, we propose a novel randomness sharing scheme between two communicating parties using an atmospheric optical channel equipped with random modulation and develop mathematical models for the common randomness source created by such a randomness-sharing scheme. Our randomness-sharing scheme provides the legitimate parties with the ability to decrease the temporal autocorrelation of the said common randomness source, which is called controllable common randomness source with memory (CCRSM), thereby enabling an enhanced secret-key extraction that can break the aforementioned restriction. Both the autocorrelation of the legitimate parties' observations of the CCRSM and the cross-correlation of the two legitimate parties' observations of the CCRSM are formulated and examined theoretically. It is found that the performing random modulation can decorrelate consecutive observations of the CCRSM obtained by the legitimate parties using a sampling interval smaller than the correlation time of turbulence-induced optical fluctuations. The cross-correlation coefficient of the eavesdropper's and legitimate parties' observations of the CCRSM is dealt with theoretically and the eavesdropping risk in the CCRSM-based key extraction is inspected for the fully-disclosed-single-modulation worst eavesdropping (FDSM-WE) scenario, partially-disclosed-single-modulation worst eavesdropping (PDSM-WE) scenario and double-modulation worst eavesdropping (DM-WE) scenario. It is shown that the FDSM-WE scenario has the highest degree of eavesdropping risk. Finally, the lowest limit of the secret-key capacity in consideration of using the CCRSM is theoretically formulated. The effects of random modulation on such the lowest limit are quantitatively analyzed from an information-theoretic perspective. It is manifested that random modulation does not harm the potential of extracting secret keys from the CCRSM's randomness component stemming from turbulence-induced optical fluctuations.
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The temporal characteristics of the free space optical communication (FSOC) turbulence fading channel are essential for analyzing the bit error rate (BER) performances and compiling the rationale of adaptive signal processing algorithms. However, the investigation is still limited since the majority of temporal sequence generation fails to combine the autocorrelation function (ACF) of the FSOC system parameters, and using the simplified formula results in the loss of detailed information for turbulence disturbances. In this paper, considering the ACF of engineering measurable atmospheric parameters, we propose a continuous-time FSOC channel fading sequence generation model that obeys the Gamma-Gamma (G-G) probability density function (PDF). First, under the influence of parameters such as transmission distance, optical wavelength, scintillation index, and atmospheric structural constant, the normalized channel fading models of ACF and PSD are established, and the numerical solution of the time-domain Gaussian correlation sequence is derived. Moreover, the light intensity generation model obeying the time-domain correlation with statistical distribution information is derived after employing the rank mapping, taking into account the association between the G-G PDF parameters and the large and small scales turbulence fading channels. Finally, the Monte Carlo numerical method is used to analyze the performances of the ACF, PDF, and PSD parameters, as well as the temporal characteristics of the generated sequence, and the matching relationships between these parameters and theory, under various turbulence intensities, propagation distances, and transverse wind speeds. Numerical results show that the proposed temporal sequence generation model highly restores the disturbance information in different frequency bands for the turbulence fading channels, and the agreement with the theoretical solution is 0.999. This study presents essential numerical simulation methods for analyzing and evaluating the temporal properties of modulated signals. When sophisticated algorithms are used to handle FSOC signals, our proposed temporal sequence model can provide communication signal experimental sample data generating techniques under various FSOC parameters, which is a crucial theoretical basis for evaluating algorithm performances.
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BACKGROUND: The influence of the safety and security of environments on early childhood development (ECD) has been under-explored. Although housing might be linked to ECD by affecting a child's health and a parent's ability to provide adequate care, only a few studies have examined this factor. We hypothesized that housing environment is associated with ECD in sub-Saharan Africa (SSA). METHODS AND FINDINGS: From 92,433 children aged 36 to 59 months who participated in Multiple Indicator Cluster Survey (MICS) in 20 SSA countries, 88,271 were tested for cognitive and social-emotional development using the Early Childhood Development Index (ECDI) questionnaire and were thus included in this cross-sectional analysis. Children's mean age was 47.2 months, and 49.8% were girls. Children were considered developmentally on track in a certain domain if they failed no more than 1 ECDI item in that domain. In each country, we used conditional logistic regression models to estimate the association between improved housing (housing with finished building materials, improved drinking water, improved sanitation facilities, and sufficient living area) and children's cognitive and social-emotional development, accounting for contextual effects and socioeconomic factors. Estimates from each country were pooled using random-effects meta-analyses. Subgroup analyses were conducted by the child's gender, maternal education, and household wealth quintiles. On-track cognitive development was associated with improved housing (odds ratio [OR] = 1.15, 95% CI 1.06 to 1.24, p < 0.001), improved drinking water (OR = 1.07, 95% CI 1.00 to 1.14, p = 0.046), improved sanitation facilities (OR = 1.15, 95% CI 1.03 to 1.28, p = 0.014), and sufficient living area (OR = 1.06, 95% CI 1.01 to 1.10, p = 0.018). On-track social-emotional development was associated with improved housing only in girls (OR = 1.14, 95% CI 1.04 to 1.25, p = 0.006). The main limitations of this study included the cross-sectional nature of the datasets and the use of the ECDI, which lacks sensitivity to measure ECD outcomes. CONCLUSIONS: In this study, we observed that improved housing was associated with on-track cognitive development and with on-track social-emotional development in girls. These findings suggest that housing improvement in SSA may be associated not only with benefits for children's physical health but also with broader aspects of healthy child development.
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Desenvolvimento Infantil , Habitação/estatística & dados numéricos , África Subsaariana , Saúde da Criança , Pré-Escolar , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Masculino , Fatores de Risco , Fatores SocioeconômicosRESUMO
BACKGROUND: As reported, 27-93 % of pregnant women take at least one drug during pregnancy. However, drug exposure during pregnancy still lacks sufficient foetal safety evidence of human origin. It is urgent to fill the knowledge gap about medication safety during pregnancy for optimization of maternal disease treatment and pregnancy drug consultation. METHODS AND ANALYSIS: The China Teratology Birth Cohort (CTBC) was established in 2019 and is a hospital-based open-ended prospective cohort study with the aim of assessing drug safety during pregnancy. Pregnant women who set up the pregnancy health records in the first trimester or who seek drug consultation regardless of gestational age in the member hospitals are recruited. Enrolled pregnant women need to be investigated four times, namely, 6-14 and 24-28 weeks of gestational age, before discharge after hospital delivery, and 28-42 days after birth. Maternal medication exposure during pregnancy is the focus of the CTBC. For drugs, information on the type, name, and route of medication; start and end time of medication; single dose; frequency of medication; dosage form; manufacturer; and reason for medication is collected. The adverse pregnancy outcomes collected in the study include birth defects, stillbirth, spontaneous abortion, preterm birth, post-term birth, low birth weight, macrosomia, small for gestational age, large for gestational age and low Apgar score. CTBC uses an electronic questionnaire for data collection and a cloud system for data management. Biological samples are collected if informed consents are obtained. Multi-level logistic regression, mixed-effect negative binomial distribution regression and spline function regression are used to explore the effect of drugs on the occurrence of birth defects. DISCUSSION: The findings of the study will assist in further understanding the risk of birth defects and other adverse pregnancy outcomes associated with maternal drug exposure and developing the optimal treatment plans and drug counselling for pregnant women. TRIAL REGISTRATION: This study was approved by the Research Ethics Committee of the West China Second Hospital of Sichuan University and registered at the Chinese Clinical Trial Registry ( http://www.chictr.org.cn/index.aspx , registration number ChiCTR1900022569 ).
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Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/epidemiologia , Exposição Materna/efeitos adversos , Preparações Farmacêuticas/administração & dosagem , Complicações na Gravidez/epidemiologia , Resultado da Gravidez/epidemiologia , China/epidemiologia , Estudos de Coortes , Anormalidades Congênitas/epidemiologia , Feminino , Macrossomia Fetal/epidemiologia , Humanos , Recém-Nascido de Baixo Peso , Recém-Nascido , Criança Pós-Termo , Recém-Nascido Pequeno para a Idade Gestacional , Gravidez , Nascimento Prematuro/epidemiologia , Estudos Prospectivos , TeratologiaRESUMO
Optical spatial-mode reception has a physical nature quite different from that of the traditional optical power-in-the-bucket (PIB) reception. The former belongs to coherent reception scheme while the latter pertains to incoherent reception scheme. Under weak-turbulence conditions, the statistical correlation between turbulence-impacted optical signals collected by a pair of adjacent spatial-mode receivers is mathematically formulated in terms of a new theoretical framework that takes into account the distinctive nature of the spatial-mode reception. The aperture Fresnel number, coherence Fresnel number, separation Fresnel number and mode Fresnel number are identified as fundamental determinative parameters in evaluation of the correlation coefficient. With the help of the obtained formulations, two analytical asymptotic formulae for the correlation coefficient are further derived under the conditions that the aperture Fresnel number is much smaller than the coherence Fresnel number and separation Fresnel number, respectively. Despite the use of asymptotic approximations in the theoretical derivation, it is found that the two asymptotic formulae indeed have utility in many situations of practical interest to us. Furthermore, Monte-Carlo-simulation-based calculations are carried out to examine the accuracy of employing the two asymptotic formulae to approximate the correlation coefficient. It is shown that the ranges of applicability of these two asymptotic formulae are mainly determined by the coherence Fresnel number and the ratio of the separation Fresnel number to the aperture Fresnel number, basically irrespective of the mode Fresnel number.
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In this study, we design a Cassegrain-based concentrator with tailored mirrors. The proposed concentrator comprises a primary optical element (POE) and a secondary optical element (SOE). The POE is a parabolic concave mirror and the SOE is a hyperbolic convex mirror. In order to achieve uniform irradiance distribution without a homogenizer, the POE is tailored and tilted to generate a uniform distribution by overlapping the energy well. The Cassegrain-based concentrator with tailored mirrors can achieve a geometric concentration ratio of 1236×, a concentration ratio of 1034×, an optical efficiency of 83.66%, an acceptance angle of ±0.38∘, a uniformity of 7.87, and an aspect ratio of 0.254.
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The Gram-negative bacterium Pseudomonas taiwanensis is a novel bacterium that uses shrimp shell waste as its sole sources of carbon and nitrogen. It is a versatile bacterium with potential for use in biological control, with activities including toxicity toward insects, fungi, and the rice pathogen Xanthomonas oryzae pv.oryzae (Xoo). In this study, the complete 5.08-Mb genome sequence of P. taiwanensis CMS was determined by a combination of NGS/Sanger sequencing and optical mapping. Comparison of optical maps of seven Pseudomonas species showed that P. taiwanensis is most closely related to P. putida KT 2400. We screened a total of 11,646 individual Tn5-transponson tagged strains to identify genes that are involved in the production and regulation of the iron-chelator pyoverdine in P. taiwanensis, which is a key anti-Xoo factor. Our results indicated that the two-component system (TCS) EnvZ/OmpR plays a positive regulatory role in the production of pyoverdine, whereas the sigma factor RpoS functions as a repressor. The knowledge of the molecular basis of the regulation of pyoverdine by P. taiwanensis provided herein will be useful for its development for use in biological control, including as an anti-Xoo agent.
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Elementos de DNA Transponíveis , Mutagênese Insercional , Oryza/microbiologia , Doenças das Plantas/microbiologia , Pseudomonas , Controle Biológico de Vetores , Pseudomonas/genética , Pseudomonas/metabolismo , Sequenciamento Completo do Genoma , Xanthomonas/crescimento & desenvolvimentoRESUMO
The instantaneous transmission coefficient, i.e., instantaneous transmittance, of a turbulent optical orbital-angular-momentum (OAM) channel is mathematically formulated as a weighted integration and is found to range between 0 and 1. Common probability distribution models for optical irradiance fluctuations with a support from 0 to ∞ are not strictly proper for statistical description of the fluctuating transmission coefficient. The novel dual Johnson S B distribution is proposed to model the statistical behavior of the fluctuating transmission coefficient. Its applicability is verified by making comparisons between the histograms of transmission-coefficient samples generated by Monte Carlo simulations and the corresponding fitted probability density functions; the values for its four independent control parameters under different conditions are obtained by the fit of the dual Johnson S B distribution to relevant simulated transmission-coefficient samples. It is found that each of the four independent control parameters of the dual Johnson S B distribution can be considered as a function of three quantities, viz., the OAM index, the Fried's atmospheric coherence width, and the ratio of the root-mean-square (RMS) OAM-beam radius to the Fried's atmospheric coherence width. The results demonstrate that the statistical distribution of the fluctuating transmission coefficient depends less on the first two quantities than on the last one. Finding a model for direct mapping from these three quantities to the four control parameters of the dual Johnson S B distribution deserves future study.
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In order to better evaluate the relationship between reciprocity and time delay of the fiber receiving system in the atmospheric turbulence channel, a time-domain signal generation mathematical model is proposed for the first time. A numerical solution of Johnson SB probability density distribution (PDF) in time-domain is creatively given for evaluating the reciprocity of both communication ends, which relates to the normalized fluctuation variance of the light intensity and the Greenwood frequency. An experiment is then carried out for verifying the time-domain signal generation model and measuring reciprocity. It shows that the excellent fitting accuracy of Johnson SB PDF signal generation model is first experimentally verified. It also indicates that the system reciprocity is improved by 10% after eliminating the system time delay. Meanwhile, the relationship between time delay and reciprocity under different atmospheric environments are analyzed and the relationship between time delay and system reciprocity at different Greenwood frequencies are discussed. This work provides a time parameter reference for the design of adaptive system and free-space optical (FSO) communication system.
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In this paper, we design a three-stage Fresnel lens concentrator with a low f number. The proposed concentrator consists of a primary optical element (POE) and a second optical element (SOE). The nine-sector three-stage Fresnel lens is composed of three types of triangular prisms: the refractive triangular prism, single total internal reflection triangular prism, and double total internal reflection triangular prism. In order to increase the uniformity and acceptance angle of the POE coupled to the SOE, the SOE is also divided into nine sectors. Finally, it is found that this nine-sector three-stage Fresnel lens concentrator can achieve a concentration ratio of 1000×; the uniformity is 25.8, optical efficiency is 81.8%, f number is 0.46, and acceptance angle is ±0.73°.
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This publisher's note amends the author listing in Appl. Opt.58, 122 (2019)APOPAI0003-693510.1364/AO.58.000122.
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BACKGROUND: Along with the rapid development of glycomic tools, the study of lectin-carbohydrate interactions has expanded, opening the way for applications in the fields of analytic, diagnostic, and drug delivery. Chitin-binding lectins (CBLs) play roles in immune defense against chitin-containing pathogens. CBLs from species of the Solanaceae family, such as tomato, potato and jimsonweed, display different binding specificities to sugar chains containing poly-N-acetyllactosamine. RESULTS: In this report, CBLs from Solanum integrifolium were isolated by ion exchange chromatography. The fractions showed hemagglutination activity (HA). The recombinant CBL in the 293F cell culture supernatant was able to inhibit the growth of Rhizoctonia solani and Colletotrichum gloeosporioide. Furthermore, the carbohydrate-binding property of CBLs was confirmed with the inhibition of HA. Binding of CBL to Spodoptera frugiperda (sf21) insect cells can partly be inhibited by N-Acetylglucosamine (GlcNAc), which is related to decrease mitochondrial membrane potential of sf21 cells. CONCLUSIONS: The results showed that CBL exhibited antifungal properties and inhibited insect cell growth, which is directly correlated to the lectin-carbohydrate interaction. Further identification and characterization of CBLs will help to broaden their scope of application in plant defense and in biomedical applications.
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Colletotrichum/efeitos dos fármacos , Fungicidas Industriais/farmacologia , Inseticidas/farmacologia , Lectinas de Plantas/genética , Rhizoctonia/efeitos dos fármacos , Solanum/genética , Spodoptera/efeitos dos fármacos , Sequência de Aminoácidos , Animais , Sequência de Bases , Quitina/metabolismo , Cromatografia por Troca Iônica , Larva/crescimento & desenvolvimento , Larva/fisiologia , Lectinas de Plantas/metabolismo , Solanum/metabolismo , Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz , Spodoptera/crescimento & desenvolvimentoRESUMO
The Orchidaceae is a diverse and ecologically important plant family. Approximately 69% of all orchid species are epiphytes, which provide diverse microhabitats for many small animals and fungi in the canopy of tropical rainforests. Moreover, many orchids are of economic importance as food flavourings or ornamental plants. Phalaenopsis aphrodite, an epiphytic orchid, is a major breeding parent of many commercial orchid hybrids. We provide a high-quality chromosome-scale assembly of the P. aphrodite genome. The total length of all scaffolds is 1025.1 Mb, with N50 scaffold size of 19.7 Mb. A total of 28 902 protein-coding genes were identified. We constructed an orchid genetic linkage map, and then anchored and ordered the genomic scaffolds along the linkage groups. We also established a high-resolution pachytene karyotype of P. aphrodite and completed the assignment of linkage groups to the 19 chromosomes using fluorescence in situ hybridization. We identified an expansion in the epiphytic orchid lineage of FRS5-like subclade associated with adaptations to the life in the canopy. Phylogenetic analysis further provides new insights into the orchid lineage-specific duplications of MADS-box genes, which might have contributed to the variation in labellum and pollinium morphology and its accessory structure. To our knowledge, this is the first orchid genome to be integrated with a SNP-based genetic linkage map and validated by physical mapping. The genome and genetic map not only offer unprecedented resources for increasing breeding efficiency in horticultural orchids but also provide an important foundation for future studies in adaptation genomics of epiphytes.
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Mapeamento Cromossômico , Cromossomos de Plantas/genética , Genoma de Planta/genética , Orchidaceae/genética , Melhoramento Vegetal/métodos , Adaptação Fisiológica/genética , Genoma de Planta/fisiologia , CariotipagemRESUMO
Common randomness arising from turbulence-induced signal fading in reciprocal optical wireless channels is a beneficial resource that can be used to generate secret keys shared by two legitimate parties. The concept of optical wireless channels using common-transverse-spatial-mode coupling (CTSMC) that can maintain perfect fading reciprocity in atmospheric turbulence is first developed in a general manner. Subsequently, by performing Monte Carlo simulations, the Johnson SB probability distribution is demonstrated to be appropriate for statistical description of turbulence-induced signal fading in an optical wireless channel constructed by use of two identical CTSMC transceivers, and the nature of correlation between signal fadings detected by two contiguous reception spatial modes is further quantitatively characterized, revealing that rapid spatial decorrelation between signal fadings observed by a legitimate party and an eavesdropper holds for scenarios of practical interest. Finally, the information theoretic capacity for generating secret keys from CTSMC-based optical wireless channels is theoretically formulated and quantitatively examined under different conditions, manifesting that the turbulence strength and average electrical signal-to-noise ratio have a noticeable combined impact on the secret key capacity, especially in the far-field case.
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We characterize the performance of the optical signal propagation model of multi-level pulse amplitude modulation (M-PAM) based on avalanche photodiode (APD) detector in the free-space link for the first time. When the number of photons absorbed by the active surface of the APD is large enough, the bit error rate (BER) performance relationship of the systems based on the signal intensity and the photon characteristics are depicted. We use the Gamma-Gamma (G-G) channel model to analysis the communication systems with joint parameter constraints, and demonstrate the atmospheric turbulence intensity, link lengths, optical wavelength, symbol transmission rate, temperature of APD and pointing errors (PEs) impact on the system average bit error rate (ABER) performance. Moreover, the relationship between signal-to-noise-ratio (SNR) and ABER rate is given. The numerical results show that the 4-PAM free-space optical (FSO) communication is suitable for medium-to-weak turbulence, and the high gain of APD can mitigate the influence of ABER. The best detection condition of the 4-PAM optical signal is at least 20 dB SNR, when the ABER is under the 7% forward error correction (FEC) limit of 3.8 × 10-3. This work provides a reference for parameter designing and evaluating in M-PAM FSO communication systems.
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Expressions for the correlation coefficient between light-flux fluctuations of two waves counter-propagating along a common path in weak turbulence are developed. Only the aperture and inner-scale Fresnel parameters are needed for evaluation of the correlation coefficient if the turbulence spectrum has no path dependence, and of the path weighting functions for the cross-covariance and variances of normalized light-flux fluctuations if the turbulence spectrum is dependent on path locations. Under the condition that atmospheric turbulence is statistically homogeneous over a path, although good correlation between light-flux fluctuations of two counter-propagating spherical waves may be achieved for a relatively small aperture Fresnel parameter or relatively large inner-scale Fresnel parameter, the correlation coefficient between light-flux fluctuations of two counter-propagating plane waves is always lower than 1 obviously. When the aperture Fresnel parameter becomes larger than the inner-scale Fresnel parameter, the inner scale of turbulence tends to play an unimportant role in determining the correlation coefficient.
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This publisher's note corrects a typo in the title in Opt. Lett.38, 1887 (2013)OPLEDP0146-959210.1364/OL.38.001887.