Detalhe da pesquisa
1.
Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.
Angew Chem Int Ed Engl
; 55(33): 9601-5, 2016 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27355874
2.
Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
Bioorg Med Chem Lett
; 23(6): 1727-31, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23414806
3.
Structural Basis for Achieving GSK-3ß Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery.
J Med Chem
; 62(21): 9600-9617, 2019 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31535859
4.
Ru/Ni Dual Catalytic Desulfinative Photoredox Csp2-Csp3 Cross-Coupling of Alkyl Sulfinate Salts and Aryl Halides.
Org Lett
; 19(24): 6566-6569, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29182291
5.
Discovery of Dap-3 polymyxin analogues for the treatment of multidrug-resistant Gram-negative nosocomial infections.
J Med Chem
; 56(12): 5079-93, 2013 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23735048
6.
Potent inhibitors of LpxC for the treatment of Gram-negative infections.
J Med Chem
; 55(2): 914-23, 2012 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22175825
7.
Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections.
J Med Chem
; 55(4): 1662-70, 2012 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22257165