Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion.

Leuzzi, Giuseppe; Vasciaveo, Alessandro; Taglialatela, Angelo; Chen, Xiao; Firestone, Tessa M; Hickman, Allison R; Mao, Wendy; Thakar, Tanay; Vaitsiankova, Alina; Huang, Jen-Wei; Cuella-Martin, Raquel; Hayward, Samuel B; Kesner, Jordan S; Ghasemzadeh, Ali; Nambiar, Tarun S; Ho, Patricia; Rialdi, Alexander; Hebrard, Maxime; Li, Yinglu; Gao, Jinmei; Gopinath, Saarang; Adeleke, Oluwatobi A; Venters, Bryan J; Drake, Charles G; Baer, Richard; Izar, Benjamin; Guccione, Ernesto; Keogh, Michael-Christopher; Guerois, Raphael; Sun, Lu; Lu, Chao; Califano, Andrea; Ciccia, Alberto.

Cell ; 187(4): 861-881.e32, 2024 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-38301646

2.

Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration.

Khazaei, Sima; Chen, Carol C L; Andrade, Augusto Faria; Kabir, Nisha; Azarafshar, Pariya; Morcos, Shahir M; França, Josiane Alves; Lopes, Mariana; Lund, Peder J; Danieau, Geoffroy; Worme, Samantha; Adnani, Lata; Nzirorera, Nadine; Chen, Xiao; Yogarajah, Gayathri; Russo, Caterina; Zeinieh, Michele; Wong, Cassandra J; Bryant, Laura; Hébert, Steven; Tong, Bethany; Sihota, Tianna S; Faury, Damien; Puligandla, Evan; Jawhar, Wajih; Sandy, Veronica; Cowan, Mitra; Nakada, Emily M; Jerome-Majewska, Loydie A; Ellezam, Benjamin; Gomes, Carolina Cavalieri; Denecke, Jonas; Lessel, Davor; McDonald, Marie T; Pizoli, Carolyn E; Taylor, Kathryn; Cocanougher, Benjamin T; Bhoj, Elizabeth J; Gingras, Anne-Claude; Garcia, Benjamin A; Lu, Chao; Campos, Eric I; Kleinman, Claudia L; Garzia, Livia; Jabado, Nada.

Cell ; 186(6): 1162-1178.e20, 2023 03 16.

Artigo em Inglês | MEDLINE | ID: mdl-36931244

3.

Functional interrogation of DNA damage response variants with base editing screens.

Cuella-Martin, Raquel; Hayward, Samuel B; Fan, Xiao; Chen, Xiao; Huang, Jen-Wei; Taglialatela, Angelo; Leuzzi, Giuseppe; Zhao, Junfei; Rabadan, Raul; Lu, Chao; Shen, Yufeng; Ciccia, Alberto.

Cell ; 184(4): 1081-1097.e19, 2021 02 18.

Artigo em Inglês | MEDLINE | ID: mdl-33606978

4.

Genomes of the Banyan Tree and Pollinator Wasp Provide Insights into Fig-Wasp Coevolution.

Zhang, Xingtan; Wang, Gang; Zhang, Shengcheng; Chen, Shuai; Wang, Yibin; Wen, Ping; Ma, Xiaokai; Shi, Yan; Qi, Rui; Yang, Yang; Liao, Zhenyang; Lin, Jing; Lin, Jishan; Xu, Xiuming; Chen, Xuequn; Xu, Xindan; Deng, Fang; Zhao, Lihua; Lee, Yi-Lun; Wang, Rong; Chen, Xiao-Yong; Lin, Yann-Rong; Zhang, Jisen; Tang, Haibao; Chen, Jin; Ming, Ray.

Cell ; 183(4): 875-889.e17, 2020 11 12.

Artigo em Inglês | MEDLINE | ID: mdl-33035453

5.

TREMendous microglial effects on neurons.

Chen, Xiao-Fen; Bu, Guojun.

Immunity ; 57(1): 1-3, 2024 Jan 09.

Artigo em Inglês | MEDLINE | ID: mdl-38198847

6.

TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration.

Zhong, Li; Sheng, Xuan; Wang, Wanbing; Li, Yanzhong; Zhuo, Rengong; Wang, Kai; Zhang, Lianshuai; Hu, Dan-Dan; Hong, Yujuan; Chen, Linting; Rao, Hengjun; Li, Tingting; Chen, Muyang; Lin, Zhihao; Zhang, Yun-Wu; Wang, Xin; Yan, Xiao-Xin; Chen, Xiaochun; Bu, Guojun; Chen, Xiao-Fen.

Immunity ; 56(8): 1794-1808.e8, 2023 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-37442133

7.

The rise of baobab trees in Madagascar.

Wan, Jun-Nan; Wang, Sheng-Wei; Leitch, Andrew R; Leitch, Ilia J; Jian, Jian-Bo; Wu, Zhang-Yan; Xin, Hai-Ping; Rakotoarinivo, Mijoro; Onjalalaina, Guy Eric; Gituru, Robert Wahiti; Dai, Can; Mwachala, Geoffrey; Bai, Ming-Zhou; Zhao, Chen-Xi; Wang, Hong-Qi; Du, Sheng-Lan; Wei, Neng; Hu, Guang-Wan; Chen, Si-Chong; Chen, Xiao-Ya; Wan, Tao; Wang, Qing-Feng.

Nature ; 629(8014): 1091-1099, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38750363

8.

Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas.

Li, Yinglu; Goldberg, Elizabeth M; Chen, Xiao; Xu, Xinjing; McGuire, John T; Leuzzi, Giuseppe; Karagiannis, Dimitris; Tate, Tiffany; Farhangdoost, Nargess; Horth, Cynthia; Dai, Esther; Li, Zhiming; Zhang, Zhiguo; Izar, Benjamin; Que, Jianwen; Ciccia, Alberto; Majewski, Jacek; Yoon, Angela J; Ailles, Laurie; Mendelsohn, Cathy Lee; Lu, Chao.

Mol Cell ; 82(20): 3901-3918.e7, 2022 10 20.

Artigo em Inglês | MEDLINE | ID: mdl-36206767

9.

Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.

Tsuchida, Connor A; Zhang, Shouyue; Doost, Mohammad Saffari; Zhao, Yuqian; Wang, Jia; O'Brien, Elizabeth; Fang, Huan; Li, Cheng-Ping; Li, Danyuan; Hai, Zhuo-Yan; Chuck, Jonathan; Brötzmann, Julian; Vartoumian, Araz; Burstein, David; Chen, Xiao-Wei; Nogales, Eva; Doudna, Jennifer A; Liu, Jun-Jie Gogo.

Mol Cell ; 82(6): 1199-1209.e6, 2022 03 17.

Artigo em Inglês | MEDLINE | ID: mdl-35219382

10.

Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages.

Lu, Yuning; Basatemur, Gemma; Scott, Ian C; Chiarugi, Davide; Clement, Marc; Harrison, James; Jugdaohsingh, Ravin; Yu, Xian; Newland, Stephen A; Jolin, Helen E; Li, Xuan; Chen, Xiao; Szymanska, Monika; Haraldsen, Guttorm; Palmer, Gaby; Fallon, Padraic G; Cohen, E Suzanne; McKenzie, Andrew N J; Mallat, Ziad.

Immunity ; 52(5): 782-793.e5, 2020 05 19.

Artigo em Inglês | MEDLINE | ID: mdl-32272082

11.

The architecture of a scrambled genome reveals massive levels of genomic rearrangement during development.

Chen, Xiao; Bracht, John R; Goldman, Aaron David; Dolzhenko, Egor; Clay, Derek M; Swart, Estienne C; Perlman, David H; Doak, Thomas G; Stuart, Andrew; Amemiya, Chris T; Sebra, Robert P; Landweber, Laura F.

Cell ; 158(5): 1187-1198, 2014 Aug 28.

Artigo em Inglês | MEDLINE | ID: mdl-25171416

12.

Subsecond periodic radio oscillations in a microquasar.

Tian, Pengfu; Zhang, Ping; Wang, Wei; Wang, Pei; Sun, Xiaohui; Liu, Jifeng; Zhang, Bing; Dai, Zigao; Yuan, Feng; Zhang, Shuangnan; Liu, Qingzhong; Jiang, Peng; Wu, Xuefeng; Zheng, Zheng; Chen, Jiashi; Li, Di; Zhu, Zonghong; Pan, Zhichen; Gan, Hengqian; Chen, Xiao; Sai, Na.

Nature ; 621(7978): 271-275, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37495697

13.

An electric molecular motor.

Zhang, Long; Qiu, Yunyan; Liu, Wei-Guang; Chen, Hongliang; Shen, Dengke; Song, Bo; Cai, Kang; Wu, Huang; Jiao, Yang; Feng, Yuanning; Seale, James S W; Pezzato, Cristian; Tian, Jia; Tan, Yu; Chen, Xiao-Yang; Guo, Qing-Hui; Stern, Charlotte L; Philp, Douglas; Astumian, R Dean; Goddard, William A; Stoddart, J Fraser.

Nature ; 613(7943): 280-286, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36631649

14.

Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks.

Chaouch, Amel; Berlandi, Johannes; Chen, Carol C L; Frey, Felice; Badini, Shireen; Harutyunyan, Ashot S; Chen, Xiao; Krug, Brian; Hébert, Steven; Jeibmann, Astrid; Lu, Chao; Kleinman, Claudia L; Hasselblatt, Martin; Lasko, Paul; Shirinian, Margret; Jabado, Nada.

Mol Cell ; 81(23): 4876-4890.e7, 2021 12 02.

Artigo em Inglês | MEDLINE | ID: mdl-34739871

15.

Atomic imaging of zeolite-confined single molecules by electron microscopy.

Shen, Boyuan; Wang, Huiqiu; Xiong, Hao; Chen, Xiao; Bosch, Eric G T; Lazic, Ivan; Qian, Weizhong; Wei, Fei.

Nature ; 607(7920): 703-707, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35831496

16.

Electron-catalysed molecular recognition.

Jiao, Yang; Qiu, Yunyan; Zhang, Long; Liu, Wei-Guang; Mao, Haochuan; Chen, Hongliang; Feng, Yuanning; Cai, Kang; Shen, Dengke; Song, Bo; Chen, Xiao-Yang; Li, Xuesong; Zhao, Xingang; Young, Ryan M; Stern, Charlotte L; Wasielewski, Michael R; Astumian, R Dean; Goddard, William A; Stoddart, J Fraser.

Nature ; 603(7900): 265-270, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35264758

17.

A single-molecule van der Waals compass.

Shen, Boyuan; Chen, Xiao; Wang, Huiqiu; Xiong, Hao; Bosch, Eric G T; Lazic, Ivan; Cai, Dali; Qian, Weizhong; Jin, Shifeng; Liu, Xin; Han, Yu; Wei, Fei.

Nature ; 592(7855): 541-544, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33883731

18.

MARK4 controls ischaemic heart failure through microtubule detyrosination.

Yu, Xian; Chen, Xiao; Amrute-Nayak, Mamta; Allgeyer, Edward; Zhao, Aite; Chenoweth, Hannah; Clement, Marc; Harrison, James; Doreth, Christian; Sirinakis, George; Krieg, Thomas; Zhou, Huiyu; Huang, Hongda; Tokuraku, Kiyotaka; Johnston, Daniel St; Mallat, Ziad; Li, Xuan.

Nature ; 594(7864): 560-565, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-34040253

19.

High-order superlattices by rolling up van der Waals heterostructures.

Zhao, Bei; Wan, Zhong; Liu, Yuan; Xu, Junqing; Yang, Xiangdong; Shen, Dingyi; Zhang, Zucheng; Guo, Chunhao; Qian, Qi; Li, Jia; Wu, Ruixia; Lin, Zhaoyang; Yan, Xingxu; Li, Bailing; Zhang, Zhengwei; Ma, Huifang; Li, Bo; Chen, Xiao; Qiao, Yi; Shakir, Imran; Almutairi, Zeyad; Wei, Fei; Zhang, Yue; Pan, Xiaoqing; Huang, Yu; Ping, Yuan; Duan, Xidong; Duan, Xiangfeng.

Nature ; 591(7850): 385-390, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33731947

20.

Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods.

Sun, Fei; Chronis, Constantinos; Kronenberg, Michael; Chen, Xiao-Fen; Su, Trent; Lay, Fides D; Plath, Kathrin; Kurdistani, Siavash K; Carey, Michael F.

Mol Cell ; 73(2): 250-263.e5, 2019 01 17.

Artigo em Inglês | MEDLINE | ID: mdl-30527662

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