Detalhe da pesquisa
1.
An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.
J Biol Chem
; 292(47): 19209-19225, 2017 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972160
2.
High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy.
Sci Rep
; 11(1): 17029, 2021 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426604
3.
Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression.
ACS Chem Neurosci
; 10(8): 3769-3777, 2019 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31330099
4.
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
Nat Med
; 25(1): 152-164, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30510257
5.
Structural Basis for Achieving GSK-3ß Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery.
J Med Chem
; 62(21): 9600-9617, 2019 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31535859
6.
Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening.
Curr Protoc Hum Genet
; 92: 21.8.1-21.8.21, 2017 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28075486
7.
Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability.
Stem Cell Reports
; 7(3): 325-340, 2016 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27594585
8.
A novel sorting motif in the glutamate transporter excitatory amino acid transporter 3 directs its targeting in Madin-Darby canine kidney cells and hippocampal neurons.
J Neurosci
; 22(24): 10643-52, 2002 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12486157
9.
A high-throughput screen for Wnt/ß-catenin signaling pathway modulators in human iPSC-derived neural progenitors.
J Biomol Screen
; 17(9): 1252-63, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22923789
10.
Insulin resistance in the middle-aged women with "Tigerish Back and Bearish Waist".
Diabetes Res Clin Pract
; 90(3): e85-7, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20970867