Detalhe da pesquisa
1.
How to Foster 'New Approach Methodology' Toxicologists.
Altern Lab Anim
; 50(1): 71-75, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-35179997
2.
The Impact of Modern Chemotherapy and Chemotherapy-Associated Liver Injuries (CALI) on Liver Function: Value of 99mTc-Labelled-Mebrofenin SPECT-Hepatobiliary Scintigraphy.
Ann Surg Oncol
; 28(4): 1959-1969, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32833150
3.
Striae Distensae: In Vitro Study and Assessment of Combined Treatment With Sodium Ascorbate and Platelet-Rich Plasma on Fibroblasts.
Aesthetic Plast Surg
; 45(3): 1282-1293, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33474574
4.
The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds.
Int J Mol Sci
; 21(10)2020 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32423144
5.
Direct and quantitative evaluation of the major human CYP contribution (fmCYP) to drug clearance using the in vitro Silensomes™ model.
Xenobiotica
; 49(1): 22-35, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29297729
6.
Direct and quantitative evaluation of the human CYP3A4 contribution (fm) to drug clearance using the in vitro SILENSOMES model.
Xenobiotica
; 47(7): 562-575, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27485383
7.
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.
Mutagenesis
; 31(4): 453-61, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26980085
8.
Functional polymer-dependent 3D culture accelerates the differentiation of HepaRG cells into mature hepatocytes.
Hepatol Res
; 46(10): 1045-57, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26724677
9.
Simultaneous detection of multiple DNA adducts in human lung samples by isotope-dilution UPLC-MS/MS.
Anal Chem
; 87(1): 641-8, 2015 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25423194
10.
Thalidomide increases human hepatic cytochrome P450 3A enzymes by direct activation of the pregnane X receptor.
Chem Res Toxicol
; 27(2): 304-308, 2014 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24460184
11.
Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.
Carcinogenesis
; 34(6): 1393-402, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23393228
12.
Drug transporter expression and activity in cryopreserved human hepatocytes isolated from chimeric TK-NOG mice with humanized livers.
Toxicol In Vitro
; 90: 105592, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37030647
13.
The Objective Stretch Marks Photonumeric Assessment Scale: A New and Complete Method to Assess Striae Distensae.
Plast Reconstr Surg
; 151(2): 307-313, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36696312
14.
OECD workshop consensus report: Ethical considerations with respect to human derived products, specifically human serum, in OECD test guidelines.
Front Toxicol
; 5: 1140698, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923365
15.
Expression and transport function of drug uptake transporters in differentiated HepaRG cells.
Mol Pharm
; 9(12): 3434-41, 2012 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22897388
16.
Expression and functional activity of cytochrome P450 enzymes in human hepatocytes with sustainable reproducibility for in vitro phenotyping studies.
Adv Pharmacol
; 95: 285-305, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35953158
17.
Contribution of Humanized Liver Chimeric Mice to the Study of Human Hepatic Drug Transporters: State of the Art and Perspectives.
Eur J Drug Metab Pharmacokinet
; 47(5): 621-637, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35793042
18.
Liposome-Mediated Gene Transfer in Differentiated HepaRG™ Cells: Expression of Liver Specific Functions and Application to the Cytochrome P450 2D6 Expression.
Cells
; 11(23)2022 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36497165
19.
Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project.
Altern Lab Anim
; 39(2): 147-71, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21639679
20.
Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells.
Drug Metab Dispos
; 38(3): 516-25, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20019244