Detalhe da pesquisa
1.
IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors.
Mol Cell
; 84(2): 202-220.e15, 2024 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38103559
2.
KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs.
Mol Cell
; 78(6): 1133-1151.e14, 2020 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32402252
3.
Opposing Functions of BRD4 Isoforms in Breast Cancer.
Mol Cell
; 78(6): 1114-1132.e10, 2020 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32446320
4.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.
Genes Dev
; 33(23-24): 1751-1774, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31753913
5.
BRD4 isoforms have distinct roles in tumour progression and metastasis in rhabdomyosarcoma.
EMBO Rep
; 25(2): 832-852, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38191874
6.
Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping.
EMBO Rep
; 24(10): e57032, 2023 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37650863
7.
The matrix protein of respiratory syncytial virus suppresses interferon signaling via RACK1 association.
J Virol
; 97(10): e0074723, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37712706
8.
Direct interaction with the BRD4 carboxyl-terminal motif (CTM) and TopBP1 is required for human papillomavirus 16 E2 association with mitotic chromatin and plasmid segregation function.
J Virol
; 97(10): e0078223, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37712702
9.
Dual-target inhibitors of bromodomain and extra-terminal proteins in cancer: A review from medicinal chemistry perspectives.
Med Res Rev
; 42(2): 710-743, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34633088
10.
PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition.
EMBO Rep
; 21(2): e48795, 2020 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31908141
11.
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.
Nature
; 529(7586): 413-417, 2016 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26735014
12.
Targeted mRNA demethylation using an engineered dCas13b-ALKBH5 fusion protein.
Nucleic Acids Res
; 48(10): 5684-5694, 2020 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32356894
13.
Blood-based biomarkers of human papillomavirus-associated cancers: A systematic review and meta-analysis.
Cancer
; 127(6): 850-864, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33270909
14.
Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver.
Mol Syst Biol
; 16(5): e9156, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407006
15.
Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting.
Mol Cell
; 49(5): 843-57, 2013 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23317504
16.
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration.
Nucleic Acids Res
; 46(13): 6576-6591, 2018 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29860315
17.
Uncovering BRD4 hyperphosphorylation associated with cellular transformation in NUT midline carcinoma.
Proc Natl Acad Sci U S A
; 114(27): E5352-E5361, 2017 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28630312
18.
A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity.
EMBO J
; 34(2): 184-99, 2015 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25425577
19.
BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells.
Nucleic Acids Res
; 45(6): 3130-3145, 2017 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27980063
20.
Phosphorylation of the Bovine Papillomavirus E2 Protein on Tyrosine Regulates Its Transcription and Replication Functions.
J Virol
; 91(2)2017 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27807239