Detalhe da pesquisa
1.
A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity.
Chembiochem
; 24(23): e202300351, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37418539
2.
SimPLIT: Simplified Sample Preparation for Large-Scale Isobaric Tagging Proteomics.
J Proteome Res
; 21(8): 1842-1856, 2022 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35848491
3.
Investigating the phosphinic acid tripeptide mimetic DG013A as a tool compound inhibitor of the M1-aminopeptidase ERAP1.
Bioorg Med Chem Lett
; 42: 128050, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33887439
4.
Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.
Nature
; 523(7559): 183-188, 2015 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26131937
5.
Experience of valgus osteotomy for neglected and failed osteosynthesis in fractures neck of femur.
Int Orthop
; 44(4): 705-713, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31650211
6.
Sternoclavicular tuberculosis: an atypical imitator of refractory shoulder pain.
Int Orthop
; 44(4): 693-698, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31451848
7.
A critical evaluation of the approaches to targeted protein degradation for drug discovery.
Drug Discov Today Technol
; 31: 5-13, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-31200859
8.
Cereblon modulator iberdomide induces degradation of the transcription factors Ikaros and Aiolos: immunomodulation in healthy volunteers and relevance to systemic lupus erythematosus.
Ann Rheum Dis
; 77(10): 1516-1523, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945920
9.
In Vivo Degradation of Crosslinked Hyaluronic Acid Fillers by Exogenous Hyaluronidases.
Dermatol Surg
; 44(8): 1075-1083, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29659410
10.
Activity of lenalidomide in mantle cell lymphoma can be explained by NK cell-mediated cytotoxicity.
Br J Haematol
; 179(3): 399-409, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28771673
11.
Lenalidomide augments actin remodeling and lowers NK-cell activation thresholds.
Blood
; 126(1): 50-60, 2015 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26002964
12.
RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1.
Blood
; 126(7): 880-90, 2015 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26109203
13.
CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL.
Blood
; 126(6): 779-89, 2015 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26002965
14.
Significance of Chilaiditi sign and Chilaiditi syndrome.
Emerg Nurse
; 25(3): 26-31, 2017 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28617114
15.
Pomalidomide in combination with dexamethasone results in synergistic anti-tumour responses in pre-clinical models of lenalidomide-resistant multiple myeloma.
Br J Haematol
; 172(6): 889-901, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26914976
16.
A phase I dose-escalation study to assess safety, tolerability, pharmacokinetics, and preliminary efficacy of the dual mTORC1/mTORC2 kinase inhibitor CC-223 in patients with advanced solid tumors or multiple myeloma.
Cancer
; 121(19): 3481-90, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26177599
17.
Congenital Epulis: A Rare Benign Jaw Tumour in a 2-Day-Old Male Baby.
Pol J Radiol
; 80: 395-7, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26379808
18.
An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin.
Br J Haematol
; 165(6): 870-82, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24635723
19.
Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).
Br J Haematol
; 164(6): 811-21, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24328678
20.
Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity.
Br J Haematol
; 164(2): 233-44, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24206017