Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9.

Maji, Basudeb; Gangopadhyay, Soumyashree A; Lee, Miseon; Shi, Mengchao; Wu, Peng; Heler, Robert; Mok, Beverly; Lim, Donghyun; Siriwardena, Sachini U; Paul, Bishwajit; Dancík, Vlado; Vetere, Amedeo; Mesleh, Michael F; Marraffini, Luciano A; Liu, David R; Clemons, Paul A; Wagner, Bridget K; Choudhary, Amit.

Cell ; 177(4): 1067-1079.e19, 2019 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-31051099

2.

Response of nitrergic system in the brain of rat conditioned to intracranial self-stimulation.

Choudhary, Amit G; Awathale, Sanjay N; Dudhabhate, Biru B; Pawar, Namrata; Jadhav, Gouri; Upadhya, Manoj A; Khedkar, Trupti; Gadhikar, Yashashree A; Sakharkar, Amul J; Subhedar, Nishikant K; Kokare, Dadasaheb M.

J Neurochem ; 2024 Mar 06.

Artigo em Inglês | MEDLINE | ID: mdl-38445395

3.

Proximity-inducing modalities: the past, present, and future.

Singh, Sameek; Tian, Wenzhi; Severance, Zachary C; Chaudhary, Santosh K; Anokhina, Viktoriya; Mondal, Basudeb; Pergu, Rajaiah; Singh, Prashant; Dhawa, Uttam; Singha, Santanu; Choudhary, Amit.

Chem Soc Rev ; 52(16): 5485-5515, 2023 Aug 14.

Artigo em Inglês | MEDLINE | ID: mdl-37477631

4.

Bifunctional Small Molecules That Induce Nuclear Localization and Targeted Transcriptional Regulation.

Gibson, William J; Sadagopan, Ananthan; Shoba, Veronika M; Choudhary, Amit; Meyerson, Matthew; Schreiber, Stuart L.

J Am Chem Soc ; 145(48): 26028-26037, 2023 12 06.

Artigo em Inglês | MEDLINE | ID: mdl-37992275

5.

Technological advancements in bio-recognition using liquid crystals: Techniques, applications, and performance.

Gangwar, Lokesh K; Mishra, Sujeet K; Choudhary, Amit; Biradar, Ashok M; Sumana, Gajjala.

Luminescence ; 38(7): 811-833, 2023 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-35347826

6.

Rational Design of Silicon-Based Zinc Ionophores.

Yamada, Kei; Deb, Arghya; Shoba, Veronika M; Lim, Donghyun; Maji, Basudeb; Modell, Ashley E; Choudhary, Amit.

Angew Chem Int Ed Engl ; 61(23): e202201698, 2022 06 07.

Artigo em Inglês | MEDLINE | ID: mdl-35385189

7.

Synthetic Reprogramming of Kinases Expands Cellular Activities of Proteins.

Shoba, Veronika M; Munkanatta Godage, Dhanushka N P; Chaudhary, Santosh K; Deb, Arghya; Siriwardena, Sachini U; Choudhary, Amit.

Angew Chem Int Ed Engl ; 61(29): e202202770, 2022 07 18.

Artigo em Inglês | MEDLINE | ID: mdl-35641438

8.

Neuropeptide CART modulates dopamine turnover in the nucleus accumbens: Insights into the anatomy of rewarding circuits.

Awathale, Sanjay N; Choudhary, Amit G; Subhedar, Nishikant K; Kokare, Dadasaheb M.

J Neurochem ; 158(5): 1172-1185, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34287909

9.

Phosphorylation-Inducing Chimeric Small Molecules.

Siriwardena, Sachini U; Munkanatta Godage, Dhanushka N P; Shoba, Veronika M; Lai, Sophia; Shi, Mengchao; Wu, Peng; Chaudhary, Santosh K; Schreiber, Stuart L; Choudhary, Amit.

J Am Chem Soc ; 142(33): 14052-14057, 2020 08 19.

Artigo em Inglês | MEDLINE | ID: mdl-32787262

10.

Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in ß-Cells.

Lee, Miseon; Maji, Basudeb; Manna, Debasish; Kahraman, Sevim; Elgamal, Ruth M; Small, Jonnell; Kokkonda, Praveen; Vetere, Amedeo; Goldberg, Jacob M; Lippard, Stephen J; Kulkarni, Rohit N; Wagner, Bridget K; Choudhary, Amit.

J Am Chem Soc ; 142(14): 6477-6482, 2020 04 08.

Artigo em Inglês | MEDLINE | ID: mdl-32175731

11.

Improved Handwritten Digit Recognition Using Convolutional Neural Networks (CNN).

Ahlawat, Savita; Choudhary, Amit; Nayyar, Anand; Singh, Saurabh; Yoon, Byungun.

Sensors (Basel) ; 20(12)2020 Jun 12.

Artigo em Inglês | MEDLINE | ID: mdl-32545702

12.

Assessment of Reliability of Cone-beam Computed Tomography in Skeletal and Dental Discrepancy.

Khandelwal, Ashok; Raghav, Shweta; Baheti, Kamalshikha; Jindal, Anurag; Bansod, Shubhanjali; Choudhary, Amit Singh.

J Contemp Dent Pract ; 21(7): 765-768, 2020 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-33020360

13.

Precision Control of CRISPR-Cas9 Using Small Molecules and Light.

Gangopadhyay, Soumyashree A; Cox, Kurt J; Manna, Debasish; Lim, Donghyun; Maji, Basudeb; Zhou, Qingxuan; Choudhary, Amit.

Biochemistry ; 58(4): 234-244, 2019 01 29.

Artigo em Inglês | MEDLINE | ID: mdl-30640437

14.

Multidimensional chemical control of CRISPR-Cas9.

Maji, Basudeb; Moore, Christopher L; Zetsche, Bernd; Volz, Sara E; Zhang, Feng; Shoulders, Matthew D; Choudhary, Amit.

Nat Chem Biol ; 13(1): 9-11, 2017 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-27820801

15.

A Singular System with Precise Dosing and Spatiotemporal Control of CRISPR-Cas9.

Manna, Debasish; Maji, Basudeb; Gangopadhyay, Soumyashree A; Cox, Kurt J; Zhou, Qingxuan; Law, Benjamin K; Mazitschek, Ralph; Choudhary, Amit.

Angew Chem Int Ed Engl ; 58(19): 6285-6289, 2019 05 06.

Artigo em Inglês | MEDLINE | ID: mdl-30834641

16.

Genome Editing: The Future Begins!

Choudhary, Amit; Goodman, Catherine.

Biochemistry ; 62(24): 3453-3454, 2023 12 19.

Artigo em Inglês | MEDLINE | ID: mdl-38111351

17.

Prolyl 4-Hydroxylase: Substrate Isosteres in Which an (E)- or (Z)-Alkene Replaces the Prolyl Peptide Bond.

Vasta, James D; Choudhary, Amit; Jensen, Katrina H; McGrath, Nicholas A; Raines, Ronald T.

Biochemistry ; 56(1): 219-227, 2017 Jan 10.

Artigo em Inglês | MEDLINE | ID: mdl-28001367

18.

Growth and stress response mechanisms underlying post-feeding regenerative organ growth in the Burmese python.

Andrew, Audra L; Perry, Blair W; Card, Daren C; Schield, Drew R; Ruggiero, Robert P; McGaugh, Suzanne E; Choudhary, Amit; Secor, Stephen M; Castoe, Todd A.

BMC Genomics ; 18(1): 338, 2017 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-28464824

19.

Minimal traumatic brain injury causes persistent changes in DNA methylation at BDNF gene promoters in rat amygdala: A possible role in anxiety-like behaviors.

Sagarkar, Sneha; Bhamburkar, Tanmayi; Shelkar, Gajanan; Choudhary, Amit; Kokare, Dadasaheb M; Sakharkar, Amul J.

Neurobiol Dis ; 106: 101-109, 2017 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-28663119

20.

A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems.

Modell, Ashley E; Siriwardena, Sachini U; Choudhary, Amit.

Biochemistry ; 59(20): 1869-1870, 2020 05 26.

Artigo em Inglês | MEDLINE | ID: mdl-32403926

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