Differential effects of stress-related and stress-unrelated humor in remitted depression.

Enhancing emotion regulation among previously depressed people is crucial for improving their resilience and reducing relapse. Therefore, emphasis is placed on determining effective regulation strategies, particularly those that, besides down-regulating negative emotions, also up-regulate positive emotions. One promising strategy, with great potential in both these respects, is humor. It is unclear, however, what type of humor is most adaptive in remitted depression. This study compared two distinct humor-based strategies: stress-related humor and stress-unrelated humor. Outpatients with remitted depression (N = 94) participated in a randomized experiment evoking personal stress and the subsequent application of stress-related humor, stress-unrelated humor, or a non-humorous regulation. They repeatedly reported positive and negative emotions (at four time points) and experienced distress (at three time points). There were also assessments of selective attention, subsequent performance, effort, and intrusive thoughts. Unlike non-humorous regulation, humor-based strategies had adaptive consequences, both immediately and after a delay; however, stress-unrelated humor was most beneficial and was the only effective strategy when attention deficits were present. Humor, especially if unrelated to stressors, might broaden the repertoire of powerful emotion regulation strategies in remitted depression. Humorous focusing on distress can be detrimental for patients with attention impairment.Clinical trial registration: The study was registered under the number ISRCTN86314628 (20/09/2021).

Neuropathological Changes in the Brains of Suicide Killers.

BACKGROUND: Homicide combined with subsequent suicide of the perpetrator is a particular form of interpersonal violence and, at the same time, a manifestation of extreme aggression directed against oneself. Despite the relatively well-described individual acts of homicide and suicide, both in terms of psychopathology and law, acts of homicide and subsequent suicide committed by the same person are not well-studied phenomena. The importance of emotional factors, including the influence of mental state deviations (psychopathology), on this phenomenon, is discussed in the literature, but still there is relatively little data with which to attempt neuropathological assessments of the brains of suicide killers. This paper is dedicated to the issue based on the neuropathological studies performed. METHODS: We analyzed a group of murder-suicides using histochemical and immunohistochemical methods. RESULTS: The results of our research indicate the presence of neurodegenerative changes including multiple deposits of ß-amyloid in the form of senile/amyloid plaques and perivascular diffuse plaques. CONCLUSIONS: Neurodegenerative changes found in the analyzed brains of suicide killers may provide an interesting starting point for a number of analyses. The presence of neurodegenerative changes at such a young age in some murderers may suggest preclinical lesions that affect cognitive functions and are associated with depressed moods.

Is it worth turning a trigger into a joke? Humor as an emotion regulation strategy in remitted depression.

AIM: Humor has long been considered as an effective emotion regulation strategy for people vulnerable to depression, but empirical evidence in this area is scarce. To address this issue, we investigated the emotional consequences of humor in remitted depressed patients and compared them with the effects of positive reappraisal and spontaneous emotion regulation. METHODS: Fifty-five patients with remitted major depression took part in a laboratory computer experiment in which they were shown negative pictures twice. First, the patients simply viewed the pictures and rated their reactions. Second, they viewed each of the pictures according to instructions, which are to (a) use humor, (b) use positive reappraisal, or (c) simply view the pictures, and then, they again rated their reactions. RESULTS: Humor was found to decrease negative emotions, increase positive emotions, and enhance the distance from adversity; it was more effective than spontaneous emotion regulation and similarly as effective as positive reappraisal. Humor was the most effortful form of emotion regulation. Patients were able to successfully produce humorous comments, and their failure to do so did not lead to worse emotional outcomes than regulating emotions spontaneously. The analyses also indicated that distancing mediates between using humor and the intensity of positive and negative emotions. CONCLUSIONS: Our findings provide preliminary empirical support for the idea that for individuals vulnerable to depression, humor can be an adaptive tool in dealing with negative responses to aversive events, and, thus, it may impair their potential of these events to trigger depressive episodes. Further studies in this area are warranted to determine the most adaptive forms of humor and analyze their effects in various depressogenic contexts.