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1.
Artigo em Inglês | MEDLINE | ID: mdl-37582204

RESUMO

Background: Absence of published literature on facial plastic and reconstructive surgery (FPRS) fellows' pursuit of academic careers hampers informed decision making for those interested in the specialty, fellowship program directors, and leaders in the American Academy of Facial Plastic and Reconstructive Surgery. Objective: To examine career choices among FPRS fellows from 2000 to 2019 and identify factors linked to academic or private practice employment after fellowship. Methods: Data from 796 fellows were analyzed, including gender, medical school, residency program, fellowship program, fellowship year, and degrees, to categorize them based on academic or nonacademic career placement. Logistic regression analyses were conducted to explore the association between demographic factors and academic career placement. Results: Forty-three percent (n = 345) obtained academic positions, with significant associations found between academic placement and additional advanced degrees, completion of fellowship training in the northeast, and residency training at an institution offering FPRS fellowship. Conclusion: Although fellows in FPRS predominantly pursue private practice, the decision to pursue academia is influenced by complex and multifactorial factors among graduates in the field.

2.
Photodermatol Photoimmunol Photomed ; 25(3): 128-31, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19438990

RESUMO

BACKGROUND: Type I mammalian collagens have several photolabile fluorescent moieties that absorb UV rays capable of reaching the dermis. We studied the temperature dependence of fluorescence fading as a marker of photochemical damage. METHODS: Collagen solutions were exposed to radiation from 0 to 240 min from either a UVG-11 hand lamp, total dose=1.173 x 10(3) J/m(2); a UVL-21 hand lamp total dose=2.030 x 10(3) J/m(2); or the fluorometer, at 325+/-5 nm, total dose=0.156 x 10(3) J/m(2). We recorded intensities at excitation/emission wavelengths 270/300, 270/330, 270/360, 270/400, 325/400, and 370/450 nm at T=9.0-59.3 degrees C. RESULTS: Results indicated simultaneous forward and reverse reactions. However, the 270/360 nm fluorophore could be analyzed as a second-order reaction. The Arrhenius curve showed two straight lines intersecting near the denaturation temperature, with helix activation energy E(a) approximately 0 and coil E(a)=7.6+/-0.6 kcal/mol (31.7+/-2.5 kJ/mol). DISCUSSION: Collagen-bound fluorophores are not just passive markers of oxidative stress and age-related damage. Their photolability to wavelengths reaching the dermis may result in pathological conditions, particularly at elevated body temperatures.


Assuntos
Colágeno Tipo I/química , Fotoquímica , Animais , Fluorescência , Camundongos , Camundongos Pelados , Temperatura
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