Detalhe da pesquisa
1.
Long-acting capsid inhibitor protects macaques from repeat SHIV challenges.
Nature
; 601(7894): 612-616, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34875675
2.
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2.
Nature
; 585(7824): 273-276, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32516797
3.
Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability.
Antimicrob Agents Chemother
; 68(4): e0137323, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38380945
4.
Perspectives on Advancing Countermeasures for Filovirus Disease: Report From a Multisector Meeting.
J Infect Dis
; 228(Suppl 7): S474-S478, 2023 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37596837
5.
No virologic resistance to bulevirtide monotherapy detected in patients through 24 weeks treatment in phase II and III clinical trials for chronic hepatitis delta.
J Hepatol
; 79(3): 657-665, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37120031
6.
Lenacapavir: A Novel, Potent, and Selective First-in-Class Inhibitor of HIV-1 Capsid Function Exhibits Optimal Pharmacokinetic Properties for a Long-Acting Injectable Antiretroviral Agent.
Mol Pharm
; 20(12): 6213-6225, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37917742
7.
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Proc Natl Acad Sci U S A
; 117(12): 6771-6776, 2020 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32054787
8.
Forgiveness of INSTI-Containing Regimens at Drug Concentrations Simulating Variable Adherence In Vitro.
Antimicrob Agents Chemother
; 66(5): e0203821, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35389236
9.
Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants.
Antimicrob Agents Chemother
; 66(6): e0022222, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35532238
10.
The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabine Are Inactive against SARS-CoV-2.
Molecules
; 27(13)2022 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35807457
11.
Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit.
J Infect Dis
; 224(Supplement_1): S1-S21, 2021 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34111271
12.
PREVAIL IV: A Randomized, Double-Blind, 2-Phase, Phase 2 Trial of Remdesivir vs Placebo for Reduction of Ebola Virus RNA in the Semen of Male Survivors.
Clin Infect Dis
; 73(10): 1849-1856, 2021 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33709142
13.
Off-Target In Vitro Profiling Demonstrates that Remdesivir Is a Highly Selective Antiviral Agent.
Antimicrob Agents Chemother
; 65(2)2021 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33229429
14.
Two-dose emtricitabine/tenofovir alafenamide plus bictegravir prophylaxis protects macaques against SHIV infection.
J Antimicrob Chemother
; 76(3): 692-698, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33202006
15.
Drug Resistance Assessment Following Administration of Respiratory Syncytial Virus (RSV) Fusion Inhibitor Presatovir to Participants Experimentally Infected With RSV.
J Infect Dis
; 222(9): 1468-1477, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31971597
16.
Remdesivir (GS-5734) Is Efficacious in Cynomolgus Macaques Infected With Marburg Virus.
J Infect Dis
; 222(11): 1894-1901, 2020 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32479636
17.
Accelerating Drug Development: Antiviral Therapies for Emerging Viruses as a Model.
Annu Rev Pharmacol Toxicol
; 57: 155-169, 2017 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27483339
18.
Identification of NK Cell Subpopulations That Differentiate HIV-Infected Subject Cohorts with Diverse Levels of Virus Control.
J Virol
; 93(7)2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30700608
19.
Toll-Like Receptor 7 Agonist GS-9620 Induces HIV Expression and HIV-Specific Immunity in Cells from HIV-Infected Individuals on Suppressive Antiretroviral Therapy.
J Virol
; 91(8)2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28179531
20.
TLR7 Agonist GS-9620 Is a Potent Inhibitor of Acute HIV-1 Infection in Human Peripheral Blood Mononuclear Cells.
Antimicrob Agents Chemother
; 61(1)2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27799218