Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Clinical targeting of HIV capsid protein with a long-acting small molecule.

Link, John O; Rhee, Martin S; Tse, Winston C; Zheng, Jim; Somoza, John R; Rowe, William; Begley, Rebecca; Chiu, Anna; Mulato, Andrew; Hansen, Derek; Singer, Eric; Tsai, Luong K; Bam, Rujuta A; Chou, Chien-Hung; Canales, Eda; Brizgys, Gediminas; Zhang, Jennifer R; Li, Jiayao; Graupe, Michael; Morganelli, Philip; Liu, Qi; Wu, Qiaoyin; Halcomb, Randall L; Saito, Roland D; Schroeder, Scott D; Lazerwith, Scott E; Bondy, Steven; Jin, Debi; Hung, Magdeleine; Novikov, Nikolai; Liu, Xiaohong; Villaseñor, Armando G; Cannizzaro, Carina E; Hu, Eric Y; Anderson, Robert L; Appleby, Todd C; Lu, Bing; Mwangi, Judy; Liclican, Albert; Niedziela-Majka, Anita; Papalia, Giuseppe A; Wong, Melanie H; Leavitt, Stephanie A; Xu, Yili; Koditek, David; Stepan, George J; Yu, Helen; Pagratis, Nikos; Clancy, Sheila; Ahmadyar, Shekeba.

Nature ; 584(7822): 614-618, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32612233

2.

Protein Footprinting and X-ray Crystallography Reveal the Interaction of PD-L1 and a Macrocyclic Peptide.

Niu, Ben; Appleby, Todd C; Wang, Ruth; Morar, Mariya; Voight, Johannes; Villaseñor, Armando G; Clancy, Sheila; Wise, Sarah; Belzile, Jean-Philippe; Papalia, Giuseppe; Wong, Melanie; Brendza, Katherine M; Lad, Latesh; Gross, Michael L.

Biochemistry ; 59(4): 541-551, 2020 02 04.

Artigo em Inglês | MEDLINE | ID: mdl-31841311

3.

Highly selective inhibition of myosin motors provides the basis of potential therapeutic application.

Sirigu, Serena; Hartman, James J; Planelles-Herrero, Vicente José; Ropars, Virginie; Clancy, Sheila; Wang, Xi; Chuang, Grace; Qian, Xiangping; Lu, Pu-Ping; Barrett, Edward; Rudolph, Karin; Royer, Christopher; Morgan, Bradley P; Stura, Enrico A; Malik, Fady I; Houdusse, Anne M.

Proc Natl Acad Sci U S A ; 113(47): E7448-E7455, 2016 11 22.

Artigo em Inglês | MEDLINE | ID: mdl-27815532

4.

Functional label-free assays for characterizing the in vitro mechanism of action of small molecule modulators of capsid assembly.

Lad, Latesh; Clancy, Sheila; Koditek, David; Wong, Melanie H; Jin, Debi; Niedziela-Majka, Anita; Papalia, Giuseppe A; Hung, Magdeleine; Yant, Stephen; Somoza, John R; Hu, Eric; Chou, Chienhung; Tse, Winston; Halcomb, Randall; Sakowicz, Roman; Pagratis, Nikos.

Biochemistry ; 54(13): 2240-8, 2015 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-25774576

5.

You gotta know when to hold 'em...

Clancy, Sheila.

Dent Assist ; 75(3): 30-3, 2006.

Artigo em Inglês | MEDLINE | ID: mdl-16808195

6.

High-throughput kinetic screening of hybridomas to identify high-affinity antibodies using bio-layer interferometry.

Lad, Latesh; Clancy, Sheila; Kovalenko, Maria; Liu, Chian; Hui, Terence; Smith, Victoria; Pagratis, Nikos.

J Biomol Screen ; 20(4): 498-507, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25425568

7.

Facing the challenge: recruitment & retention of staff.

Clancy, Sheila.

J Mass Dent Soc ; 53(1): 18-21, 2004.

Artigo em Inglês | MEDLINE | ID: mdl-15131874

8.

Volunteer: give 'til it feels good!

Clancy, Sheila A.

Dent Assist ; 75(1): 8-10, 2006.

Artigo em Inglês | MEDLINE | ID: mdl-16594496

9.

Differential regulation of WASP and N-WASP by Cdc42, Rac1, Nck, and PI(4,5)P2.

Tomasevic, Nenad; Jia, Zhiheng; Russell, Alan; Fujii, Toby; Hartman, James J; Clancy, Sheila; Wang, Manping; Beraud, Christophe; Wood, Kenneth W; Sakowicz, Roman.

Biochemistry ; 46(11): 3494-502, 2007 Mar 20.

Artigo em Inglês | MEDLINE | ID: mdl-17302440

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