Detalhe da pesquisa
1.
Thyclotides, tetrahydrofuran-modified peptide nucleic acids that efficiently penetrate cells and inhibit microRNA-21.
Nucleic Acids Res
; 50(19): 10839-10856, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36215040
2.
Conformational constraints of cyclopentane peptide nucleic acids facilitate tunable binding to DNA.
Nucleic Acids Res
; 49(2): 713-725, 2021 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33406227
3.
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
J Biol Chem
; 294(46): 17654-17668, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31481464
4.
Variation of Tetrahydrofurans in Thyclotides Enhances Oligonucleotide Binding and Cellular Uptake of Peptide Nucleic Acids.
JACS Au
; 3(7): 1952-1964, 2023 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37502163
5.
Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen.
ACS Pharmacol Transl Sci
; 5(10): 993-1006, 2022 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36268125
6.
Chemical Features Important for Activity in a Class of Inhibitors Targeting the Wip1 Flap Subdomain.
ChemMedChem
; 13(9): 894-901, 2018 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29476592
7.
Restoring Anticancer Immune Response by Targeting Tumor-Derived Exosomes With a HSP70 Peptide Aptamer.
J Natl Cancer Inst
; 108(3)2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26598503
8.
Interindividual variability and co-regulation of DNA methylation differ among blood cell populations.
Epigenetics
; 7(12): 1421-34, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23151460