Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Identification of multipotent luminal progenitor cells in human prostate organoid cultures.

Karthaus, Wouter R; Iaquinta, Phillip J; Drost, Jarno; Gracanin, Ana; van Boxtel, Ruben; Wongvipat, John; Dowling, Catherine M; Gao, Dong; Begthel, Harry; Sachs, Norman; Vries, Robert G J; Cuppen, Edwin; Chen, Yu; Sawyers, Charles L; Clevers, Hans C.

Cell ; 159(1): 163-175, 2014 Sep 25.

Artigo em Inglês | MEDLINE | ID: mdl-25201529

2.

Programs for the persistence, vigilance and control of human CD8⁺ lung-resident memory T cells.

Hombrink, Pleun; Helbig, Christina; Backer, Ronald A; Piet, Berber; Oja, Anna E; Stark, Regina; Brasser, Giso; Jongejan, Aldo; Jonkers, René E; Nota, Benjamin; Basak, Onur; Clevers, Hans C; Moerland, Perry D; Amsen, Derk; van Lier, René A W.

Nat Immunol ; 17(12): 1467-1478, 2016 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-27776108

3.

Erratum: Programs for the persistence, vigilance and control of human CD8⁺ lung-resident memory T cells.

Hombrink, Pleun; Helbig, Christina; Backer, Ronald A; Piet, Berber; Oja, Anna E; Stark, Regina; Brasser, Giso; Jongejan, Aldo; Jonkers, René E; Nota, Benjamin; Basak, Onur; Clevers, Hans C; Moerland, Perry D; Amsen, Derk; van Lier, René A W.

Nat Immunol ; 18(2): 246, 2017 01 19.

Artigo em Inglês | MEDLINE | ID: mdl-28102212

4.

Mouse and human urothelial cancer organoids: A tool for bladder cancer research.

Mullenders, Jasper; de Jongh, Evelien; Brousali, Anneta; Roosen, Mieke; Blom, Jan P A; Begthel, Harry; Korving, Jeroen; Jonges, Trudy; Kranenburg, Onno; Meijer, Richard; Clevers, Hans C.

Proc Natl Acad Sci U S A ; 116(10): 4567-4574, 2019 03 05.

Artigo em Inglês | MEDLINE | ID: mdl-30787188

5.

Paneth cells: maestros of the small intestinal crypts.

Clevers, Hans C; Bevins, Charles L.

Annu Rev Physiol ; 75: 289-311, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23398152

6.

WNT signalling and haematopoiesis: a WNT-WNT situation.

Staal, Frank J T; Clevers, Hans C.

Nat Rev Immunol ; 5(1): 21-30, 2005 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-15630426

7.

The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer.

Medina, Pedro P; Castillo, Sandra D; Blanco, Sandra; Sanz-Garcia, Marta; Largo, Cristina; Alvarez, Sara; Yokota, Jun; Gonzalez-Neira, Ana; Benitez, Javier; Clevers, Hans C; Cigudosa, Juan C; Lazo, Pedro A; Sanchez-Cespedes, Montse.

Hum Mol Genet ; 18(7): 1343-52, 2009 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-19153074

8.

Organoids: Avatars for Personalized Medicine.

Clevers, Hans C.

Keio J Med ; 68(4): 95, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31875622

9.

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis.

Berkers, Gitte; van Mourik, Peter; Vonk, Annelotte M; Kruisselbrink, Evelien; Dekkers, Johanna F; de Winter-de Groot, Karin M; Arets, Hubertus G M; Marck-van der Wilt, Rozemarijn E P; Dijkema, Jasper S; Vanderschuren, Maaike M; Houwen, Roderick H J; Heijerman, Harry G M; van de Graaf, Eduard A; Elias, Sjoerd G; Majoor, Christof J; Koppelman, Gerard H; Roukema, Jolt; Bakker, Marleen; Janssens, Hettie M; van der Meer, Renske; Vries, Robert G J; Clevers, Hans C; de Jonge, Hugo R; Beekman, Jeffrey M; van der Ent, Cornelis K.

Cell Rep ; 26(7): 1701-1708.e3, 2019 02 12.

Artigo em Inglês | MEDLINE | ID: mdl-30759382

10.

Wnt signaling in the thymus.

Staal, Frank J T; Clevers, Hans C.

Curr Opin Immunol ; 15(2): 204-8, 2003 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-12633671

11.

SCA-1 Expression Level Identifies Quiescent Hematopoietic Stem and Progenitor Cells.

Morcos, Mina N F; Schoedel, Kristina B; Hoppe, Anja; Behrendt, Rayk; Basak, Onur; Clevers, Hans C; Roers, Axel; Gerbaulet, Alexander.

Stem Cell Reports ; 8(6): 1472-1478, 2017 06 06.

Artigo em Inglês | MEDLINE | ID: mdl-28506535

12.

FANTOM5 CAGE profiles of human and mouse samples.

Noguchi, Shuhei; Arakawa, Takahiro; Fukuda, Shiro; Furuno, Masaaki; Hasegawa, Akira; Hori, Fumi; Ishikawa-Kato, Sachi; Kaida, Kaoru; Kaiho, Ai; Kanamori-Katayama, Mutsumi; Kawashima, Tsugumi; Kojima, Miki; Kubosaki, Atsutaka; Manabe, Ri-Ichiroh; Murata, Mitsuyoshi; Nagao-Sato, Sayaka; Nakazato, Kenichi; Ninomiya, Noriko; Nishiyori-Sueki, Hiromi; Noma, Shohei; Saijyo, Eri; Saka, Akiko; Sakai, Mizuho; Simon, Christophe; Suzuki, Naoko; Tagami, Michihira; Watanabe, Shoko; Yoshida, Shigehiro; Arner, Peter; Axton, Richard A; Babina, Magda; Baillie, J Kenneth; Barnett, Timothy C; Beckhouse, Anthony G; Blumenthal, Antje; Bodega, Beatrice; Bonetti, Alessandro; Briggs, James; Brombacher, Frank; Carlisle, Ailsa J; Clevers, Hans C; Davis, Carrie A; Detmar, Michael; Dohi, Taeko; Edge, Albert S B; Edinger, Matthias; Ehrlund, Anna; Ekwall, Karl; Endoh, Mitsuhiro; Enomoto, Hideki.

Sci Data ; 4: 170112, 2017 08 29.

Artigo em Inglês | MEDLINE | ID: mdl-28850106

13.

The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas.

Wilson, Maria E; Yang, Katherine Y; Kalousova, Anna; Lau, Janet; Kosaka, Yasuhiro; Lynn, Francis C; Wang, Juehu; Mrejen, Caroline; Episkopou, Vasso; Clevers, Hans C; German, Michael S.

Diabetes ; 54(12): 3402-9, 2005 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-16306355

14.

Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors.

Agarwal, Supreet; Hynes, Paul G; Tillman, Heather S; Lake, Ross; Abou-Kheir, Wassim G; Fang, Lei; Casey, Orla M; Ameri, Amir H; Martin, Philip L; Yin, Juan Juan; Iaquinta, Phillip J; Karthaus, Wouter R; Clevers, Hans C; Sawyers, Charles L; Kelly, Kathleen.

Cell Rep ; 13(10): 2147-58, 2015 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-26628377

15.

Retromer dependent recycling of the Wnt secretion factor Wls is dispensable for stem cell maintenance in the mammalian intestinal epithelium.

de Groot, Reinoud E A; Farin, Henner F; Macurková, Marie; van Es, Johan H; Clevers, Hans C; Korswagen, Hendrik C.

PLoS One ; 8(10): e76971, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-24130821

16.

DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus.

Kaaij, Lucas T J; van de Wetering, Marc; Fang, Fang; Decato, Benjamin; Molaro, Antoine; van de Werken, Harmen J G; van Es, Johan H; Schuijers, Jurian; de Wit, Elzo; de Laat, Wouter; Hannon, Gregory J; Clevers, Hans C; Smith, Andrew D; Ketting, René F.

Genome Biol ; 14(5): R50, 2013 May 28.

Artigo em Inglês | MEDLINE | ID: mdl-23714178

17.

The R-spondin protein family.

de Lau, Wim B M; Snel, Berend; Clevers, Hans C.

Genome Biol ; 13(3): 242, 2012.

Artigo em Inglês | MEDLINE | ID: mdl-22439850

18.

Identification of primary MAFB target genes in multiple myeloma.

van Stralen, Esther; van de Wetering, Marc; Agnelli, Luca; Neri, Antonino; Clevers, Hans C; Bast, Bert J E G.

Exp Hematol ; 37(1): 78-86, 2009 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-19013005

19.

Suppression of tubulin polymerization by the LKB1-microtubule-associated protein/microtubule affinity-regulating kinase signaling.

Kojima, Yasushi; Miyoshi, Hiroyuki; Clevers, Hans C; Oshima, Masanobu; Aoki, Masahiro; Taketo, Makoto M.

J Biol Chem ; 282(32): 23532-40, 2007 Aug 10.

Artigo em Inglês | MEDLINE | ID: mdl-17573348

20.

Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia.

Haramis, Anna-Pavlina G; Hurlstone, Adam; van der Velden, Yme; Begthel, Harry; van den Born, Maaike; Offerhaus, G Johan A; Clevers, Hans C.

EMBO Rep ; 7(4): 444-9, 2006 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-16439994

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