Detalhe da pesquisa
1.
A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology.
Cell
; 177(5): 1217-1231.e18, 2019 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31006530
2.
Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation.
Cell
; 172(1-2): 234-248.e17, 2018 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29307489
3.
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.
Cell
; 160(4): 745-758, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25662011
4.
Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis.
Nature
; 579(7798): 279-283, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32132708
5.
Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis.
Proc Natl Acad Sci U S A
; 119(10): e2122287119, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35238637
6.
Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice.
Diabetologia
; 66(3): 567-578, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36456864
7.
N-acylphosphatidylethanolamine, a gut- derived circulating factor induced by fat ingestion, inhibits food intake.
Cell
; 135(5): 813-24, 2008 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19041747
8.
Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease.
Proc Natl Acad Sci U S A
; 117(13): 7347-7354, 2020 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32179679
9.
Metabolic control analysis of hepatic glycogen synthesis in vivo.
Proc Natl Acad Sci U S A
; 117(14): 8166-8176, 2020 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32188779
10.
Acetate mediates a microbiome-brain-ß-cell axis to promote metabolic syndrome.
Nature
; 534(7606): 213-7, 2016 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27279214
11.
Validation of a Gas Chromatography-Mass Spectrometry Method for the Measurement of the Redox State Metabolic Ratios Lactate/Pyruvate and ß-Hydroxybutyrate/Acetoacetate in Biological Samples.
Int J Mol Sci
; 22(9)2021 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33946157
12.
Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice.
J Lipid Res
; 61(12): 1565-1576, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32907986
13.
Adipose glucocorticoid action influences whole-body metabolism via modulation of hepatic insulin action.
FASEB J
; 33(7): 8174-8185, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30922125
14.
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Nature
; 513(7519): 559-63, 2014 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25043024
15.
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Nature
; 510(7506): 542-6, 2014 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24847880
16.
Anti-inflammatory effects of oestrogen mediate the sexual dimorphic response to lipid-induced insulin resistance.
J Physiol
; 597(15): 3885-3903, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31206703
17.
Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents.
Hepatology
; 68(6): 2197-2211, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29790582
18.
In vivo studies on the mechanism of methylene cyclopropyl acetic acid and methylene cyclopropyl glycine-induced hypoglycemia.
Biochem J
; 475(6): 1063-1074, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29483297
19.
Argininosuccinate synthetase regulates hepatic AMPK linking protein catabolism and ureagenesis to hepatic lipid metabolism.
Proc Natl Acad Sci U S A
; 113(24): E3423-30, 2016 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27247419
20.
Decreased VMAT2 in the pancreas of humans with type 2 diabetes mellitus measured in vivo by PET imaging.
Diabetologia
; 61(12): 2598-2607, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29721633