Detalhe da pesquisa
1.
The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease.
Nat Immunol
; 18(1): 26-35, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27893701
2.
Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity.
Immunity
; 47(5): 943-958.e9, 2017 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29150240
3.
TNFRs and Control of Chronic LCMV Infection: Implications for Therapy.
Trends Immunol
; 36(11): 697-708, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26481667
4.
Privileged Antigen Presentation in Splenic B Cell Follicles Maximizes T Cell Responses in Prime-Boost Vaccination.
J Immunol
; 196(11): 4587-95, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27183620
5.
GITR intrinsically sustains early type 1 and late follicular helper CD4 T cell accumulation to control a chronic viral infection.
PLoS Pathog
; 11(1): e1004517, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25590581
6.
The contextual role of TNFR family members in CD8(+) T-cell control of viral infections.
Immunol Rev
; 255(1): 125-48, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23947352
7.
Anti-GITR agonist therapy intrinsically enhances CD8 T cell responses to chronic lymphocytic choriomeningitis virus (LCMV), thereby circumventing LCMV-induced downregulation of costimulatory GITR ligand on APC.
J Immunol
; 193(10): 5033-43, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25281716
8.
GITR-dependent regulation of 4-1BB expression: implications for T cell memory and anti-4-1BB-induced pathology.
J Immunol
; 190(9): 4627-39, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23536631
9.
Tumor reactive γδ T cells contribute to a complete response to PD-1 blockade in a Merkel cell carcinoma patient.
Nat Commun
; 15(1): 1094, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38321065
10.
Real-world treatment patterns and survival outcomes for treated biliary tract cancer patients using administrative databases in Ontario.
J Gastrointest Oncol
; 14(4): 1806-1816, 2023 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37720427
11.
A real-world retrospective analysis of the management of metastatic castrate-resistant prostate cancer in Ontario, Canada from 2010 - 2018.
Urol Oncol
; 41(3): 146.e13-146.e22, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36641303
12.
Real-world treatment patterns, clinical outcomes, and health care resource utilization in advanced unresectable hepatocellular carcinoma.
Can Liver J
; 5(4): 476-492, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-38144405
13.
Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity.
Nat Commun
; 12(1): 5137, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34446728
14.
Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumab.
Nat Cancer
; 1(9): 873-881, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35121950
15.
An interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE).
J Immunother Cancer
; 7(1): 72, 2019 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30867072
16.
Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors.
Genome Med
; 10(1): 81, 2018 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30382883
17.
Requisite role for Nck adaptors in cardiovascular development, endothelial-to-mesenchymal transition, and directed cell migration.
Mol Cell Biol
; 35(9): 1573-87, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25691664
18.
Cell-specific and context-dependent effects of GITR in cancer, autoimmunity, and infection.
Cytokine Growth Factor Rev
; 25(2): 91-106, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24484736
19.
Oncolytic vesicular stomatitis virus quantitatively and qualitatively improves primary CD8+ T-cell responses to anticancer vaccines.
Oncoimmunology
; 2(8): e26013, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24083086
20.
Costimulation, a surprising connection for immunotherapy.
Science
; 355(6332): 1373-1374, 2017 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28360282