Detalhe da pesquisa
1.
Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis.
J Immunol
; 206(6): 1395-1404, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33547170
2.
Neutral ceramidase-active site inhibitor chemotypes and binding modes.
Bioorg Chem
; 139: 106747, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37531819
3.
Measurement of neutral ceramidase activity in vitro and in vivo.
Anal Biochem
; 643: 114577, 2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35134389
4.
Loss of acid ceramidase in myeloid cells suppresses intestinal neutrophil recruitment.
FASEB J
; 32(5): 2339-2353, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29259036
5.
Functions of neutral ceramidase in the Golgi apparatus.
J Lipid Res
; 59(11): 2116-2125, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30154232
6.
Role of neutral ceramidase in colon cancer.
FASEB J
; 30(12): 4159-4171, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27609772
7.
Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis.
Prostaglandins Other Lipid Mediat
; 130: 47-56, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28377281
8.
Sphingolipids in colon cancer.
Biochim Biophys Acta
; 1841(5): 773-82, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24060581
9.
Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 ß-cell survival.
Biochim Biophys Acta
; 1831(2): 251-62, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23085009
10.
Role of Sphingosine Kinase 1 in Glucolipotoxicity-Induced Early Activation of Autophagy in INS-1 Pancreatic ß Cells.
Cells
; 13(7)2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38607078
11.
Mass Spectrometry and Pharmacological Approaches to Measuring Cooption and Reciprocal Activation of Receptor Tyrosine Kinases.
Proteomes
; 11(2)2023 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37368466
12.
Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 ß-cells.
Biochem J
; 438(1): 177-89, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21592087
13.
Glycogen synthase kinase 3 involvement in the excessive proinflammatory response to LPS in patients with decompensated cirrhosis.
J Hepatol
; 55(4): 784-93, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21334395
14.
Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening.
SLAS Discov
; 26(1): 113-121, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32734807
15.
Ex vivo effects of high-density lipoprotein exposure on the lipopolysaccharide-induced inflammatory response in patients with severe cirrhosis.
Hepatology
; 49(1): 175-84, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19053046
16.
Neutral ceramidase: Advances in mechanisms, cell regulation, and roles in cancer.
Adv Biol Regul
; 71: 141-146, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30389354
17.
AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells.
Oncogene
; 37(28): 3852-3863, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29662189
18.
Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances ß-cell function of obese Zucker rats.
Mol Metab
; 8: 23-36, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29233519
19.
Ceramidases, roles in sphingolipid metabolism and in health and disease.
Adv Biol Regul
; 63: 122-131, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27771292
20.
Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells.
Sci Rep
; 7: 44867, 2017 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28322247