Detalhe da pesquisa
1.
Increased Cell Proliferation as a Key Event in Chemical Carcinogenesis: Application in an Integrated Approach for the Testing and Assessment of Non-Genotoxic Carcinogenesis.
Int J Mol Sci
; 24(17)2023 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686053
2.
Key Characteristics of Human Hepatotoxicants as a Basis for Identification and Characterization of the Causes of Liver Toxicity.
Hepatology
; 74(6): 3486-3496, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34105804
3.
Sex-, Age-, and Race/Ethnicity-Dependent Variations in Drug-Processing and NRF2-Regulated Genes in Human Livers.
Drug Metab Dispos
; 49(1): 111-119, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33162398
4.
A Gene Expression Biomarker Predicts Heat Shock Factor 1 Activation in a Gene Expression Compendium.
Chem Res Toxicol
; 34(7): 1721-1737, 2021 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34170685
5.
A Gene Expression Biomarker Identifies Chemical Modulators of Estrogen Receptor α in an MCF-7 Microarray Compendium.
Chem Res Toxicol
; 34(2): 313-329, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33405908
6.
Expression of cytochrome P450 isozyme transcripts and activities in human livers.
Xenobiotica
; 51(3): 279-286, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33350342
7.
Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells.
Arch Toxicol
; 95(5): 1631-1645, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33770205
8.
Thresholds Derived From Common Measures in Rat Studies Are Predictive of Liver Tumorigenic Chemicals.
Toxicol Pathol
; 48(7): 857-874, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33084515
9.
Identification of potential endocrine disrupting chemicals using gene expression biomarkers.
Toxicol Appl Pharmacol
; 380: 114683, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31325560
10.
Identification of p53 Activators in a Human Microarray Compendium.
Chem Res Toxicol
; 32(9): 1748-1759, 2019 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31397557
11.
Carcinogenicity of aspartame, methyleugenol, and isoeugenol.
Lancet Oncol
; 24(8): 848-850, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37454664
12.
Adverse outcome pathway-driven identification of rat liver tumorigens in short-term assays.
Toxicol Appl Pharmacol
; 356: 99-113, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30048669
13.
The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions.
Arch Toxicol
; 92(1): 83-119, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29197930
14.
Human relevance of rodent liver tumors: Key insights from a Toxicology Forum workshop on nongenotoxic modes of action.
Regul Toxicol Pharmacol
; 92: 1-7, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29113941
15.
Letter to the Editors regarding "10% body weight (gain) change as criterion for the maximum tolerated dose: A critical analysis".
Regul Toxicol Pharmacol
; 139: 105362, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36828242
16.
Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.
Crit Rev Toxicol
; 44(1): 1-49, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24180432
17.
A 50-gene biomarker identifies estrogen receptor-modulating chemicals in a microarray compendium.
Chem Biol Interact
; 394: 110952, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38570061
18.
Hepatic Transcriptome Comparative In Silico Analysis Reveals Similar Pathways and Targets Altered by Legacy and Alternative Per- and Polyfluoroalkyl Substances in Mice.
Toxics
; 11(12)2023 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38133364
19.
Identifying Human Specific Adverse Outcome Pathways of Per- and Polyfluoroalkyl Substances Using Liver-Chimeric Humanized Mice.
bioRxiv
; 2023 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36778348
20.
Transcriptional ontogeny of the developing liver.
BMC Genomics
; 13: 33, 2012 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22260730