Detalhe da pesquisa
1.
Defining a Cancer Dependency Map.
Cell
; 170(3): 564-576.e16, 2017 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28753430
2.
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML.
Cell
; 165(2): 303-16, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27058663
3.
The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity.
Nat Immunol
; 16(5): 495-504, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25848864
4.
Cancer vulnerabilities unveiled by genomic loss.
Cell
; 150(4): 842-54, 2012 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22901813
5.
ß-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.
Cell
; 151(7): 1457-73, 2012 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23245941
6.
Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN activity.
Blood
; 132(12): 1293-1303, 2018 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30042095
7.
In vivo discovery of immunotherapy targets in the tumour microenvironment.
Nature
; 506(7486): 52-7, 2014 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24476824
8.
PIK3CA mutant tumors depend on oxoglutarate dehydrogenase.
Proc Natl Acad Sci U S A
; 114(17): E3434-E3443, 2017 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28396387
9.
Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden.
Proc Natl Acad Sci U S A
; 114(51): E10981-E10990, 2017 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29203668
10.
Synthetic lethal screening in the mammalian central nervous system identifies Gpx6 as a modulator of Huntington's disease.
Proc Natl Acad Sci U S A
; 112(1): 268-72, 2015 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25535386
11.
Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation.
Proc Natl Acad Sci U S A
; 112(2): 512-7, 2015 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25548173
12.
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Nature
; 476(7360): 346-50, 2011 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21760589
13.
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.
Proc Natl Acad Sci U S A
; 111(51): E5564-73, 2014 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25512523
14.
The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection.
PLoS Pathog
; 10(2): e1003904, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24516381
15.
Reply to Haffner et al.: DNA hypomethylation renders tumors more immunogenic.
Proc Natl Acad Sci U S A
; 115(37): E8583-E8584, 2018 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30181297
16.
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.
Proc Natl Acad Sci U S A
; 108(30): 12372-7, 2011 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21746896
17.
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin.
Commun Biol
; 7(1): 426, 2024 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38589567
18.
Hyper-Dependence on NHEJ Enables Synergy between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma.
Clin Cancer Res
; 29(24): 5128-5139, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37773632
19.
The methyltransferase domain of DNMT1 is an essential domain in acute myeloid leukemia independent of DNMT3A mutation.
Commun Biol
; 5(1): 1174, 2022 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36329185
20.
Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion.
Blood Adv
; 6(6): 1780-1796, 2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35016204