Detalhe da pesquisa
1.
Systematic identification of structure-specific protein-protein interactions.
Mol Syst Biol
; 20(6): 651-675, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38702390
2.
Tau depletion in human neurons mitigates Aß-driven toxicity.
Mol Psychiatry
; 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38361127
3.
Variation on a theme: mapping microglial heterogeneity.
Trends Genet
; 37(12): 1050-1052, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34563398
4.
ADAM17-triggered TNF signalling protects the ageing Drosophila retina from lipid droplet-mediated degeneration.
EMBO J
; 39(17): e104415, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32715522
5.
Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart.
Development
; 148(3)2021 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33462113
6.
Aberrant inflammatory responses to type I interferon in STAT2 or IRF9 deficiency.
J Allergy Clin Immunol
; 150(4): 955-964.e16, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35182547
7.
Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality.
Glia
; 70(7): 1267-1288, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35262217
8.
Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair.
Hum Mol Genet
; 29(13): 2200-2217, 2020 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504093
9.
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages.
EMBO J
; 37(12)2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29789389
10.
Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder.
Mol Psychiatry
; 26(9): 5252-5265, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32404948
11.
Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.
Hum Mol Genet
; 28(12): 2001-2013, 2019 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753527
12.
Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-ß oligomers.
J Biol Chem
; 294(17): 7085-7097, 2019 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30872401
13.
A causal role for TRESK loss of function in migraine mechanisms.
Brain
; 142(12): 3852-3867, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31742594
14.
Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening.
Int J Mol Sci
; 21(13)2020 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32645954
15.
RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes.
Neurobiol Dis
; 129: 56-66, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085228
16.
An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2.
Neurobiol Dis
; 127: 512-526, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30954703
17.
Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons.
Hum Mol Genet
; 26(22): 4441-4450, 2017 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28973645
18.
Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
Hum Mol Genet
; 26(3): 552-566, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096185
19.
Stem cell modeling of mitochondrial parkinsonism reveals key functions of OPA1.
Ann Neurol
; 83(5): 915-925, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29604226
20.
Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.
Hum Mol Genet
; 25(5): 989-1000, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26740550