Detalhe da pesquisa
1.
Structural abnormalities revealed by magnetic resonance imaging in rats prenatally exposed to methylazoxymethanol acetate parallel cerebral pathology in schizophrenia.
Synapse
; 65(5): 393-403, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20803618
2.
Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.
J Neurosci
; 27(39): 10578-87, 2007 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-17898229
3.
Structure-activity studies and analgesic efficacy of N-(3-pyridinyl)-bridged bicyclic diamines, exceptionally potent agonists at nicotinic acetylcholine receptors.
J Med Chem
; 50(15): 3627-44, 2007 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-17585748
4.
A-366833: a novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane alpha4beta2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models.
Biochem Pharmacol
; 74(8): 1253-62, 2007 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17854775
5.
Synthesis and structure-activity relationships of 3,8-diazabicyclo[4.2.0]octane ligands, potent nicotinic acetylcholine receptor agonists.
J Med Chem
; 49(26): 7843-53, 2006 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17181167
6.
Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment.
Neurosci Lett
; 410(1): 15-9, 2006 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-17055644
7.
A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats.
Pharmacol Biochem Behav
; 82(1): 148-55, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16154186
8.
Peripheral and central sites of action for A-85380 in the spinal nerve ligation model of neuropathic pain.
Pain
; 103(3): 269-276, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12791433
9.
In vitro and in vivo effects of an alpha3 neuronal nicotinic acetylcholine receptor antisense oligonucleotide.
Brain Res Mol Brain Res
; 129(1-2): 67-79, 2004 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-15469883
10.
H3 receptor blockade by thioperamide enhances cognition in rats without inducing locomotor sensitization.
Psychopharmacology (Berl)
; 167(4): 363-72, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12682709
11.
Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia.
Psychopharmacology (Berl)
; 176(3-4): 312-9, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15179541
12.
Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan.
Behav Brain Res
; 153(1): 69-76, 2004 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-15219708
13.
Mechanism of action of A-85380 in an animal model of depression.
Prog Neuropsychopharmacol Biol Psychiatry
; 28(4): 723-30, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15276699
14.
Supraspinal and systemic administration of the nicotinic-cholinergic agonist (+/-)-epibatidine has inhibitory effects on C-fiber reflexes in the rat.
Brain Res Bull
; 64(4): 323-30, 2004 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15561467
15.
Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease.
Brain Res
; 1311: 136-47, 2010 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19944081
16.
Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptors.
Br J Pharmacol
; 158(6): 1486-94, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19845675
17.
Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties.
CNS Neurosci Ther
; 14(1): 65-82, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18482100
18.
A-85380: a pharmacological probe for the preclinical and clinical investigation of the alphabeta neuronal nicotinic acetylcholine receptor.
CNS Drug Rev
; 12(2): 100-12, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16958984
19.
Preclinical profiling and safety studies of ABT-769: a compound with potential for broad-spectrum antiepileptic activity.
Epilepsia
; 46(9): 1349-61, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16146429