Detalhe da pesquisa
1.
Treatment Trials in Young Patients with Chronic Obstructive Pulmonary Disease and Pre-Chronic Obstructive Pulmonary Disease Patients: Time to Move Forward.
Am J Respir Crit Care Med
; 205(3): 275-287, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34672872
2.
The novel bronchodilator navafenterol: a phase 2a, multicentre, randomised, double-blind, placebo-controlled crossover trial in COPD.
Eur Respir J
; 59(4)2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503985
3.
INEXAS: A Phase 2 Randomized Trial of On-demand Inhaled Interferon Beta-1a in Severe Asthmatics.
Clin Exp Allergy
; 51(2): 273-283, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33091192
4.
Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.
Respir Res
; 18(1): 82, 2017 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28468623
5.
Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury.
Annu Rev Physiol
; 73: 479-501, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21054166
6.
Use of CompEx in eosinophilic patients with severe, uncontrolled asthma on benralizumab.
ERJ Open Res
; 10(2)2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38500798
7.
A relation between TGF-ß and mast cell tryptase in experimental emphysema models.
Biochim Biophys Acta
; 1822(7): 1154-60, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22481124
8.
Physical activity end-points in trials of chronic respiratory diseases: summary of evidence.
ERJ Open Res
; 8(1)2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-35295234
9.
Chitin is a size-dependent regulator of macrophage TNF and IL-10 production.
J Immunol
; 182(6): 3573-82, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19265136
10.
Acidic mammalian chitinase regulates epithelial cell apoptosis via a chitinolytic-independent mechanism.
J Immunol
; 182(8): 5098-106, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19342690
11.
Chitin particles are multifaceted immune adjuvants.
Am J Respir Crit Care Med
; 182(12): 1482-91, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20656945
12.
Complexity of design in early phase respiratory clinical trials; evaluating impact of primary endpoints and sponsor size.
Contemp Clin Trials Commun
; 22: 100793, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34136720
13.
TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.
J Immunol
; 181(6): 4279-86, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18768886
14.
COPDCompEx: A novel composite endpoint for COPD exacerbations to enable faster clinical development.
Respir Med
; 173: 106175, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33032168
15.
Impact of season and geography on CompEx Asthma: a composite end-point for exacerbations.
ERJ Open Res
; 6(4)2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33123561
16.
A novel endpoint for exacerbations in asthma to accelerate clinical development: a post-hoc analysis of randomised controlled trials.
Lancet Respir Med
; 5(7): 577-590, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28583396
17.
Marked stem cell factor expression in the airways of lung transplant recipients.
Respir Res
; 7: 90, 2006 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-16780589
18.
Stem cell factor and its receptor c-Kit as targets for inflammatory diseases.
Eur J Pharmacol
; 533(1-3): 327-40, 2006 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16483568
19.
Stem cell factor expression, mast cells and inflammation in asthma.
Fundam Clin Pharmacol
; 20(1): 21-39, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16448392
20.
Novel biomarkers in asthma: chemokines and chitinase-like proteins.
Curr Opin Allergy Clin Immunol
; 9(1): 60-6, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19532094