Detalhe da pesquisa
1.
Systematic Investigation of the Scope of Transannular C-H Heteroarylation of Cyclic Secondary Amines for Synthetic Application in Medicinal Chemistry.
J Org Chem
; 85(10): 6747-6760, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32295349
2.
Real-Time Biological Annotation of Synthetic Compounds.
J Am Chem Soc
; 138(28): 8920-7, 2016 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27398798
3.
Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake.
Bioorg Med Chem Lett
; 25(12): 2594-8, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25958245
4.
Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake.
Bioorg Med Chem Lett
; 25(10): 2100-5, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25900219
5.
Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.
J Org Chem
; 78(11): 5160-71, 2013 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23692141
6.
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Bioorg Med Chem Lett
; 23(6): 1834-8, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23403082
7.
Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction.
Bioorg Med Chem Lett
; 23(10): 3039-43, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23562243
8.
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries.
J Comput Aided Mol Des
; 27(5): 455-68, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23585218
9.
ML212: A small-molecule probe for investigating fluconazole resistance mechanisms in Candida albicans.
Beilstein J Org Chem
; 9: 1501-7, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23946849
10.
Grand challenge commentary: Accessing new chemical space for 'undruggable' targets.
Nat Chem Biol
; 6(12): 861-3, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21079589
11.
Development of small-molecule probes that selectively kill cells induced to express mutant RAS.
Bioorg Med Chem Lett
; 22(4): 1822-6, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22297109
12.
Overcoming fluconazole resistance in Candida albicans clinical isolates with tetracyclic indoles.
Bioorg Med Chem Lett
; 22(9): 3362-5, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22497765
13.
Identification of a selective small molecule inhibitor of breast cancer stem cells.
Bioorg Med Chem Lett
; 22(10): 3571-4, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22503247
14.
Non-invasive Imaging of Antisense Oligonucleotides in the Brain via In Vivo Click Chemistry.
Mol Imaging Biol
; 24(6): 940-949, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35655109
15.
Diversity-oriented synthesis of 13- to 18-membered macrolactams via ring-closing metathesis.
J Org Chem
; 76(19): 8042-8, 2011 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21875084
16.
Identification of small-molecule inhibitors of Trypansoma cruzi replication.
Bioorg Med Chem Lett
; 21(23): 7197-200, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22018462
17.
Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates.
Bioorg Med Chem Lett
; 21(18): 5502-5, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21802942
18.
Practical asymmetric synthesis of ß-hydroxy γ-amino acids via complimentary aldol reactions.
Tetrahedron
; 67(34): 6131-6137, 2011 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822337
19.
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.
J Am Chem Soc
; 132(47): 16962-76, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21067169
20.
Skeletal diversity through radical cyclization of tetrahydropyridine scaffolds.
Org Lett
; 9(19): 3849-52, 2007 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-17713919