Oral Conditions of Elders and Middle-aged Individuals with Multiple Myeloma.

AIM AND OBJECTIVE: The aim and objective of the present study was to assess the oral conditions of middle-aged and elderly individuals with multiple myeloma. MATERIALS AND METHODS: This cross-sectional, observational study was carried out in the city of Fortaleza, Ceará, in Northeastern Brazil. An oral examination was performed with 19 patients with multiple myeloma, and information on gender, age, diagnosis, diagnosis duration (months/years), and treatment duration (months/years) were collected. The gingival bleeding index (GBI) and probing depth (PD) were measured to check for periodontal disease, and the decayed, missing, and filled teeth (DMFT) index was used to assess dental conditions. Inferential statistics were also used, as well as the Mann-Whitney test to compare genders and continuous variables and the chi-square test for comparisons among the same groups with categorical variables. All statistical tests adopted a significance threshold of p ≤0.05. RESULTS: Among the 19 patients analyzed, 10 (52.6%) were elderly, and 9 (47.4%), middle-aged. The mean age of the participants was 63.4 ± 11.7 years, ranging from 48 to 83 years old. Statistical significance was found regarding missing teeth in the elderly group (p = 0.037), restored teeth in the middle-aged group (p = 0.029), and gingival bleeding among women (p = 0.050). Hyposalivation was observed in 89.5% of the individuals, of which 68.4% were characterized as moderate to severe. CONCLUSION: Better dental conditions were observed in the middle-aged group when compared to the elderly. Men presented the lowest GBI values. The salivary flow of patients with multiple myeloma was reduced, and most of them showed moderate to severe hyposalivation. It can be assumed that such a situation is caused by the action of drugs, chemotherapy, or even age. Improvements in the oral health of these patients are needed in order to promote a better quality of life. CLINICAL SIGNIFICANCE: Knowledge of the oral manifestations of multiple myeloma patients is essential to assist in the early diagnosis of these alterations, as well as to propose an adequate treatment plan, aiming to improve these patients' quality of life.

What are the autism research priorities of autistic adults in Scotland?

LAY ABSTRACT: Although research has the potential to improve autistic people's lives, lots of funding goes towards research looking at topics which autistic people say has little impact in their everyday lives. Autistic people's lives can be different depending on where they live, and Scotland is a unique country in many ways. We wanted to find out which topics autistic people in Scotland want to see research on. Our team of autistic and non-autistic researchers (including university-based and community researchers) created a survey where 225 autistic adults rated and ranked the importance of possible research topics and shared their thoughts on what topics mattered to them. The five most important topics were mental health and well-being, identifying and diagnosing autistic people, support services (including healthcare and social care), non-autistic people's knowledge and attitudes and issues impacting autistic women. The three least important topics were genetics or biological aspects of autism, autism treatments/interventions and causes of autism. Our findings indicate that autistic people in Scotland want research to focus on things that matter to their day-to-day lives. Also, the Scottish government says they will be listening to autistic people in their latest policy plans, and we believe that considering autistic people's research priorities is an important part of this. Our findings also add to growing calls for change to happen in how and what autism researchers do research on.

Diretrizes de Enfermagem na Assistência Pré-hospitalar para Urgências/Emergências Cardiovasculares / Guidelines for nursing in prehospital care for cardiovascular emergencies

Objetivo: elaborar diretrizes para o cuidado clínico de enfermagem na assistência pré hospitalar em urgências e emergências cardiovasculares no paciente adulto. Metodologia: revisão integrativa da literatura, validação teórica, de constructo e do instrumento; neste artigo será apresentada a etapa de validação teórica realizada por juízes técnicos e de conteúdo. Resultados: obteve-se CCI acima de 0,75 assegurando a pertinência teórica, consistência, clareza, objetividade, vocabulário e aplicabilidade clínica. Resultados: obteve-se um diretriz organizada nos tópicos: avaliação das condições segurança da cena e anamnese; exame físico e condutas terapêuticas de enfermagem no APH em urgências e emergências cardiovasculares no paciente adulto. As intervenções estão direcionadas para as situações: primeiro atendimento às urgências e emergências clínicas em ambiente pré-hospitalar ou em transferências inter-hospitalares. Conclusões: constitui-se uma estratégia que pode qualificar suas intervenções junto às urgências e emergências cardiovasculares. As diretrizes elaboradas surgem como instrumento capaz de qualificar a assistência de enfermagem no APH. (AU)

Objective: to develop guidelines for clinical nursing care in prehospital care in emergencies and cardiovascular emergencies in adult patients. Methodology: integrative literature review, theoretical validation, construct and instrument; In this article the theoretical validation stage will be presented by technical judges and content. Results: ICC above 0.75 was obtained, ensuring theoretical pertinence, consistency, clarity, objectivity, vocabulary and clinical applicability. An organized guideline was obtained on the following topics: evaluation of the conditions scene safety and anamnesis; physical examination and therapeutic management of nursing in HPS in emergencies and cardiovascular emergencies in the adult patient. The interventions are directed to situations: first emergency care and clinical emergencies in a prehospital environment or in interhospital transfers. Conclusion: a strategy is formed that can qualify its interventions in the emergency and cardiovascular emergencies. The elaborated guidelines appear as an instrument capable of qualifying the nursing care in the APH. (AU)

Objetivo: elaborar directrices para el cuidado clínico de enfermería en la asistencia prehospitalaria en urgencias y emergencias cardiovasculares en el paciente adulto. Metodología: revisión integrativa de la literatura, validación teórica, de constructo y del instrumento; en este artículo se presentará la etapa de validación teórica realizada por jueces técnicos y de contenido. Resultados: se obtuvo CCI por encima de 0,75 asegurando la pertinencia teórica, consistencia, claridad, objetividad, vocabulario y aplicabilidad clínica. Se obtuvo una directriz organizada en los siguientes tópicos: evaluación de las condiciones de seguridad de la escena y anamnesis; examen físico y conductas terapéuticas de enfermería en el APH en urgencias y emergencias cardiovasculares en el paciente adulto. Las intervenciones están dirigidas a las situaciones: primera atención a las urgencias y emergencias clínicas en ambiente prehospitalario o en transferencias interhospitalarias. Conclusión: se constituye una estrategia que puede calificar sus intervenciones ante las urgencias y emergencias cardiovasculares. Las directrices elaboradas surgen como instrumento capaz de calificar la asistencia de enfermería en el APH. (AU)