Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis.

Weiss, Andy; Murdoch, Caitlin C; Edmonds, Katherine A; Jordan, Matthew R; Monteith, Andrew J; Perera, Yasiru R; Rodríguez Nassif, Aslin M; Petoletti, Amber M; Beavers, William N; Munneke, Matthew J; Drury, Sydney L; Krystofiak, Evan S; Thalluri, Kishore; Wu, Hongwei; Kruse, Angela R S; DiMarchi, Richard D; Caprioli, Richard M; Spraggins, Jeffrey M; Chazin, Walter J; Giedroc, David P; Skaar, Eric P.

Cell ; 185(12): 2148-2163.e27, 2022 06 09.

Artigo em Inglês | MEDLINE | ID: mdl-35584702

2.

The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability.

Hallacli, Erinc; Kayatekin, Can; Nazeen, Sumaiya; Wang, Xiou H; Sheinkopf, Zoe; Sathyakumar, Shubhangi; Sarkar, Souvarish; Jiang, Xin; Dong, Xianjun; Di Maio, Roberto; Wang, Wen; Keeney, Matthew T; Felsky, Daniel; Sandoe, Jackson; Vahdatshoar, Aazam; Udeshi, Namrata D; Mani, D R; Carr, Steven A; Lindquist, Susan; De Jager, Philip L; Bartel, David P; Myers, Chad L; Greenamyre, J Timothy; Feany, Mel B; Sunyaev, Shamil R; Chung, Chee Yeun; Khurana, Vikram.

Cell ; 185(12): 2035-2056.e33, 2022 06 09.

Artigo em Inglês | MEDLINE | ID: mdl-35688132

3.

ER-to-Golgi protein delivery through an interwoven, tubular network extending from ER.

Weigel, Aubrey V; Chang, Chi-Lun; Shtengel, Gleb; Xu, C Shan; Hoffman, David P; Freeman, Melanie; Iyer, Nirmala; Aaron, Jesse; Khuon, Satya; Bogovic, John; Qiu, Wei; Hess, Harald F; Lippincott-Schwartz, Jennifer.

Cell ; 184(9): 2412-2429.e16, 2021 04 29.

Artigo em Inglês | MEDLINE | ID: mdl-33852913

4.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Huttlin, Edward L; Bruckner, Raphael J; Navarrete-Perea, Jose; Cannon, Joe R; Baltier, Kurt; Gebreab, Fana; Gygi, Melanie P; Thornock, Alexandra; Zarraga, Gabriela; Tam, Stanley; Szpyt, John; Gassaway, Brandon M; Panov, Alexandra; Parzen, Hannah; Fu, Sipei; Golbazi, Arvene; Maenpaa, Eila; Stricker, Keegan; Guha Thakurta, Sanjukta; Zhang, Tian; Rad, Ramin; Pan, Joshua; Nusinow, David P; Paulo, Joao A; Schweppe, Devin K; Vaites, Laura Pontano; Harper, J Wade; Gygi, Steven P.

Cell ; 184(11): 3022-3040.e28, 2021 05 27.

Artigo em Inglês | MEDLINE | ID: mdl-33961781

5.

Checkpoint Responses to DNA Double-Strand Breaks.

Waterman, David P; Haber, James E; Smolka, Marcus B.

Annu Rev Biochem ; 89: 103-133, 2020 06 20.

Artigo em Inglês | MEDLINE | ID: mdl-32176524

6.

Quantitative Proteomics of the Cancer Cell Line Encyclopedia.

Nusinow, David P; Szpyt, John; Ghandi, Mahmoud; Rose, Christopher M; McDonald, E Robert; Kalocsay, Marian; Jané-Valbuena, Judit; Gelfand, Ellen; Schweppe, Devin K; Jedrychowski, Mark; Golji, Javad; Porter, Dale A; Rejtar, Tomas; Wang, Y Karen; Kryukov, Gregory V; Stegmeier, Frank; Erickson, Brian K; Garraway, Levi A; Sellers, William R; Gygi, Steven P.

Cell ; 180(2): 387-402.e16, 2020 01 23.

Artigo em Inglês | MEDLINE | ID: mdl-31978347

7.

SUSD2 suppresses CD8⁺ T cell antitumor immunity by targeting IL-2 receptor signaling.

Zhao, Bao; Gong, Weipeng; Ma, Anjun; Chen, Jianwen; Velegraki, Maria; Dong, Hong; Liu, Zihao; Wang, Lingling; Okimoto, Tamio; Jones, Devin M; Lei, Yu L; Long, Meixiao; Oestreich, Kenneth J; Ma, Qin; Xin, Gang; Carbone, David P; He, Kai; Li, Zihai; Wen, Haitao.

Nat Immunol ; 23(11): 1588-1599, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-36266363

8.

Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis.

Ast, Tslil; Meisel, Joshua D; Patra, Shachin; Wang, Hong; Grange, Robert M H; Kim, Sharon H; Calvo, Sarah E; Orefice, Lauren L; Nagashima, Fumiaki; Ichinose, Fumito; Zapol, Warren M; Ruvkun, Gary; Barondeau, David P; Mootha, Vamsi K.

Cell ; 177(6): 1507-1521.e16, 2019 05 30.

Artigo em Inglês | MEDLINE | ID: mdl-31031004

9.

Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias.

Raundhal, Mahesh; Ghosh, Shrestha; Myers, Samuel A; Cuoco, Michael S; Singer, Meromit; Carr, Steven A; Waikar, Sushrut S; Bonventre, Joseph V; Ritz, Jerome; Stone, Richard M; Steensma, David P; Regev, Aviv; Glimcher, Laurie H.

Nat Immunol ; 22(4): 520-529, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33753942

10.

The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies.

Viengkhou, Barney; Hayashida, Emina; McGlasson, Sarah; Emelianova, Katie; Forbes, Deborah; Wiseman, Stewart; Wardlaw, Joanna; Verdillo, Rovin; Irani, Sarosh R; Duffy, Darragh; Piehl, Fredrik; Loo, Lipin; Pagenstecher, Axel; Neely, G Greg; Crow, Yanick J; Campbell, Iain L; Hunt, David P J; Hofer, Markus J.

Immunity ; 2024 Jun 11.

Artigo em Inglês | MEDLINE | ID: mdl-38878770

11.

Metazoan MicroRNAs.

Bartel, David P.

Cell ; 173(1): 20-51, 2018 03 22.

Artigo em Inglês | MEDLINE | ID: mdl-29570994

12.

A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain.

Kleaveland, Benjamin; Shi, Charlie Y; Stefano, Joanna; Bartel, David P.

Cell ; 174(2): 350-362.e17, 2018 07 12.

Artigo em Inglês | MEDLINE | ID: mdl-29887379

13.

Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched.

Zhang, Yunxiao; Bulkley, David P; Xin, Yao; Roberts, Kelsey J; Asarnow, Daniel E; Sharma, Ashutosh; Myers, Benjamin R; Cho, Wonhwa; Cheng, Yifan; Beachy, Philip A.

Cell ; 175(5): 1352-1364.e14, 2018 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-30415841

14.

The molecular basis underpinning the potency and specificity of MAIT cell antigens.

Awad, Wael; Ler, Geraldine J M; Xu, Weijun; Keller, Andrew N; Mak, Jeffrey Y W; Lim, Xin Yi; Liu, Ligong; Eckle, Sidonia B G; Le Nours, Jérôme; McCluskey, James; Corbett, Alexandra J; Fairlie, David P; Rossjohn, Jamie.

Nat Immunol ; 21(4): 400-411, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-32123373

15.

Mechanotransduction via endothelial adhesion molecule CD31 initiates transmigration and reveals a role for VEGFR2 in diapedesis.

Fu, Tao; Sullivan, David P; Gonzalez, Annette M; Haynes, Maureen E; Dalal, Prarthana J; Rutledge, Nakisha S; Tierney, Abigail L; Yescas, Julia A; Weber, Evan W; Muller, William A.

Immunity ; 56(10): 2311-2324.e6, 2023 Oct 10.

Artigo em Inglês | MEDLINE | ID: mdl-37643615

16.

Widespread Influence of 3'-End Structures on Mammalian mRNA Processing and Stability.

Wu, Xuebing; Bartel, David P.

Cell ; 169(5): 905-917.e11, 2017 May 18.

Artigo em Inglês | MEDLINE | ID: mdl-28525757

17.

Intestinal Epithelial and Intraepithelial T Cell Crosstalk Mediates a Dynamic Response to Infection.

Hoytema van Konijnenburg, David P; Reis, Bernardo S; Pedicord, Virginia A; Farache, Julia; Victora, Gabriel D; Mucida, Daniel.

Cell ; 171(4): 783-794.e13, 2017 Nov 02.

Artigo em Inglês | MEDLINE | ID: mdl-28942917

18.

Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway.

Dulloo, Iqbal; Tellier, Michael; Levet, Clémence; Chikh, Anissa; Zhang, Boyan; Blaydon, Diana C; Webb, Catherine M; Kelsell, David P; Freeman, Matthew.

Mol Cell ; 84(2): 277-292.e9, 2024 Jan 18.

Artigo em Inglês | MEDLINE | ID: mdl-38183983

19.

Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating.

Zhang, Yalan; Zhang, Xiao-Feng; Fleming, Matthew R; Amiri, Anahita; El-Hassar, Lynda; Surguchev, Alexei A; Hyland, Callen; Jenkins, David P; Desai, Rooma; Brown, Maile R; Gazula, Valeswara-Rao; Waters, Michael F; Large, Charles H; Horvath, Tamas L; Navaratnam, Dhasakumar; Vaccarino, Flora M; Forscher, Paul; Kaczmarek, Leonard K.

Cell ; 165(2): 434-448, 2016 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-26997484

20.

ALL-tRNAseq enables robust tRNA profiling in tissue samples.

Scheepbouwer, Chantal; Aparicio-Puerta, Ernesto; Gomez-Martin, Cristina; Verschueren, Heleen; van Eijndhoven, Monique; Wedekind, Laurine E; Giannoukakos, Stavros; Hijmering, Nathalie; Gasparotto, Lisa; van der Galien, Hilde T; van Rijn, Roos S; Aronica, Eleonora; Kibbelaar, Robby; Heine, Vivi M; Wesseling, Pieter; Noske, David P; Vandertop, W Peter; de Jong, Daphne; Pegtel, D Michiel; Hackenberg, Michael; Wurdinger, Tom; Gerber, Alan; Koppers-Lalic, Danijela.

Genes Dev ; 37(5-6): 243-257, 2023 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-36810209

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