Detalhe da pesquisa
1.
PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease.
Cell
; 185(11): 1943-1959.e21, 2022 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35545089
2.
Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.
Cell
; 157(2): 472-485, 2014 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24725412
3.
Bi-allelic TTI1 variants cause an autosomal-recessive neurodevelopmental disorder with microcephaly.
Am J Hum Genet
; 110(3): 499-515, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36724785
4.
Molecular recording of calcium signals via calcium-dependent proximity labeling.
Nat Chem Biol
; 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38658655
5.
PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease.
Cell
; 144(5): 689-702, 2011 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21376232
6.
The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior.
Cell
; 145(2): 284-99, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21496646
7.
Poly(ADP-ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation.
FASEB J
; 38(6): e23556, 2024 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38498348
8.
PARIS undergoes liquid-liquid phase separation and poly(ADP-ribose)-mediated solidification.
EMBO Rep
; 24(11): e56166, 2023 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37870275
9.
STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy.
Proc Natl Acad Sci U S A
; 119(15): e2118819119, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35394877
10.
Amelioration of pathologic α-synuclein-induced Parkinson's disease by irisin.
Proc Natl Acad Sci U S A
; 119(36): e2204835119, 2022 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36044549
11.
A high-affinity cocaine binding site associated with the brain acid soluble protein 1.
Proc Natl Acad Sci U S A
; 119(16): e2200545119, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35412917
12.
Blocking the Self-Destruct Program of Dopamine Neurons through Macrophage Migration Inhibitory Factor Nuclease Inhibition.
Mov Disord
; 39(4): 644-650, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38396375
13.
Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease.
Proc Natl Acad Sci U S A
; 118(26)2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34172566
14.
Parkinson Disease: Translating Insights from Molecular Mechanisms to Neuroprotection.
Pharmacol Rev
; 73(4): 33-97, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663684
15.
Protein Translation in the Pathogenesis of Parkinson's Disease.
Int J Mol Sci
; 25(4)2024 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38397070
16.
The Absence of Parkin Does Not Promote Dopamine or Mitochondrial Dysfunction in PolgAD257A/D257A Mitochondrial Mutator Mice.
J Neurosci
; 42(49): 9263-9277, 2022 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36280265
17.
Neurotoxic reactive astrocytes are induced by activated microglia.
Nature
; 541(7638): 481-487, 2017 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28099414
18.
T cells from patients with Parkinson's disease recognize α-synuclein peptides.
Nature
; 546(7660): 656-661, 2017 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28636593
19.
Erratum: T cells from patients with Parkinson's disease recognize α-synuclein peptides.
Nature
; 549(7671): 292, 2017 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28905919
20.
USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing.
Nucleic Acids Res
; 49(19): 11083-11102, 2021 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34614178